Sinorhizobium medicae: Smed_0718
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Entry
Smed_0718 CDS
T00555
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smd
Sinorhizobium medicae
Pathway
smd00290
Valine, leucine and isoleucine biosynthesis
smd00620
Pyruvate metabolism
smd01100
Metabolic pathways
smd01110
Biosynthesis of secondary metabolites
smd01210
2-Oxocarboxylic acid metabolism
smd01230
Biosynthesis of amino acids
Module
smd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Smed_0718
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Smed_0718
Enzymes [BR:
smd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Smed_0718
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
EF-hand_14
Motif
Other DBs
NCBI-ProteinID:
ABR59574
UniProt:
A6U7E4
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All DBs
Position
769374..770990
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AA seq
538 aa
AA seq
DB search
MTRQRIYLFDTTLRDGQQTPGIDFSVEDKIAIASMLDQFGMDYVEGGYPGANPTDTEFFK
RKRTENASFVAFGMTKRAGVSASNDPGLNALLGAQSDAICLVAKSWDYHVDVALGCSNEE
NLENIRASVEAVVASGREAMVDCEHFFDGFKANPAYALACATTAFEAGARWVVLCDTNGG
TQPPEIREIVSAVIAAGVPGASLGIHAHNDTGQAVANSLAAVEAGVRQIQGTLNGIGERC
GNANLVTLVATLSLKDAYSSRFETAIDAERLQELTKLAHAFDELLNRSPDPQAPYVGASA
FATKAGIHASALLKDPRTYEHVAPESVGNLRKVMVSDQGGKANFINALKRRGITVSKDDP
RLDKLISIVKEREATGYAYEGADASFALLASRILGTVPDFFHVESFRVMVERRFDANGKL
KTVSEAVVRVIVDGETMMSVAEGHGPVNALDLALRKDLGKYQSEIADLELADYKVRILNG
GTEAVTRVLIESTDRTGARWWTVGVSDNIIDASFQALMDSIVYKLLKNRDQVGLIAAE
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgaccaggcaacgcatctacctcttcgacacgactcttcgagatgggcagcagacgcct
ggtatcgatttttccgtcgaggacaagattgcgatcgcgtccatgctcgatcaattcggc
atggattacgtcgaaggcggatatccgggcgccaatccgaccgataccgagttcttcaag
cgcaaacgcaccgagaatgcctcattcgtggcgttcggaatgaccaagcgcgctggcgta
tccgcctccaacgatcctggcctgaatgcgttgctgggcgcgcaaagcgatgcgatctgt
cttgttgccaagagctgggactatcatgtcgacgtggcgctcggttgctccaatgaggag
aatctcgaaaatatccgtgcgtcggtggaggcggtggttgcatccgggcgcgaggcgatg
gtcgattgcgagcatttcttcgacggcttcaaggcgaaccccgcctatgcgctcgcatgc
gcgacaacggcttttgaagccggcgcacgctgggtggtgctttgcgacacgaatggcggg
acgcagccgccggaaatccgagagatcgtctcggccgtgatagcggccggcgttcccggt
gcaagtctcggtatccacgcgcataacgatacggggcaggcggtggccaattctctggcg
gcggtcgaagccggcgttcgtcagatccagggcacgctgaacggcatcggcgagcgctgc
ggcaacgccaacctcgtaacgctggttgcgacgctttcgttgaaggatgcctattcgagc
cgcttcgaaacggcaatcgacgccgaaaggctccaggaactgaccaagctcgcgcatgct
ttcgacgagttgctcaaccgttcgcccgatcctcaggcgccctatgtcggcgcttcggcc
ttcgccaccaaagccggaattcacgcctcggcgctgctgaaggatccgaggacctacgag
catgtcgcgccggaaagcgtcggcaatctgcgcaaggtcatggtctccgatcagggcggc
aaggccaatttcatcaatgcgctgaagcggcgtggcatcaccgtctccaaggacgatccg
cggctggacaagttgatttcgatcgtcaaggagcgggaggcaacaggctatgcctatgaa
ggcgcggatgcgagctttgcgcttctcgccagccgaatactcggcacagtgcccgacttc
ttccatgttgagagcttccgggtcatggtcgagcgccgcttcgacgccaacggcaagctg
aagacggtgtcggaggcggtggtcagggtcatcgtcgatggcgaaacgatgatgtccgtt
gccgaggggcatggccccgtcaacgcactcgacctcgcactccggaaggacttggggaag
taccagtccgaaatcgccgatctggagcttgccgattacaaggtgcgcatcctcaacgga
ggcaccgaggcggtcacccgcgtgctgatcgaatcgaccgatcgcaccggcgcacgctgg
tggacggtcggcgtgtccgacaacatcatcgatgcctcatttcaggcattgatggacagt
atcgtctacaagctgctcaaaaatcgcgatcaggtcggattgatcgccgccgagtag
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