KEGG   Sinorhizobium meliloti 1021: SMc01053
Entry
SMc01053          CDS       T00058                                 
Symbol
cysG
Name
(GenBank) Probable siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
sme  Sinorhizobium meliloti 1021
Pathway
sme00860  Porphyrin metabolism
sme01100  Metabolic pathways
sme01110  Biosynthesis of secondary metabolites
sme01120  Microbial metabolism in diverse environments
sme01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:sme00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    SMc01053 (cysG)
Enzymes [BR:sme01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     SMc01053 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     SMc01053 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     SMc01053 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M BSD Radical_SAM
Other DBs
NCBI-ProteinID: CAC46048
UniProt: Q92Q80
LinkDB
Position
1583260..1584717
AA seq 485 aa
MSQKLSVFPAFFRVAQKSVAVFGNGDEAFAKLRLLLNTEARIVAYADRPEPAFDAFLDAN
NIETVREPFGAHQVEGSVLVFAATGDAALDRVVVTAARERKIPANAVDQPDYCDFLTPAL
VNRAPVAVAIGTEGAGPVLAQMIRAQIDQLLSPSLGIVASLAANYRDAVERLVPRGVARR
VFWRRFFSGPVADQVALGDLASARREASRLLDAAGGVAGHVWLVGAGPGAEDLLTLRAQR
VMMEADAIVYDALVPQAIVDMGRRDAERLSVGKRKGCHTKSQDEINQLLVKLAGEGKRVV
RLKSGDPLVYGRAGEEMAALREAGISYEVVPGITSAFAAAADFELPLTLRGVASSLVFTT
GHDLTGSVLPDWARLAVSGATIAVYMGRTVAASVASRLMQAGLPQDTTVAVIENASRAER
RLLHGTLRDLPDLEARTELDGPVMVIIGEAVAGANFERSEPLAAGRTKYSGASKVSAKRT
EQIWN
NT seq 1458 nt   +upstreamnt  +downstreamnt
atgtcgcagaaattgtccgtctttccggcattctttcgcgtcgcgcagaaaagcgtggcg
gtgttcggcaatggggacgaggccttcgccaagttacggttgctgctgaacaccgaggcg
cgcatcgtcgcctatgcggatcgcccggaaccggcattcgatgcttttctggatgccaac
aatatcgagaccgtgcgcgaaccctttggggctcatcaggtcgaaggctccgtcctcgtc
tttgccgcaaccggcgatgcggcgcttgaccgcgttgtcgtgactgcggcgcgcgagcgg
aaaatccccgcaaatgccgtggatcagccggactattgcgatttcctcacgccggcactc
gtcaaccgggcgcccgtcgcagttgcgatcggcaccgaaggggcagggccggttctggcg
cagatgatccgcgcgcagatcgatcaattgctgtcgccgtccttgggtatcgttgcctct
ttggctgcgaactatcgcgacgccgtcgagcgcctcgtgccgcgcggcgtcgctcggcgt
gtcttctggcgccgcttcttctcgggccctgtggcggatcaagtagcgctcggcgatctt
gcatccgcgcgccgcgaggcctcgaggcttctggatgccgcggggggcgtggccggccat
gtgtggctggtcggcgccggaccgggcgccgaagacctgctgacgctccgggcgcagcgc
gtgatgatggaagcggatgccatcgtttatgatgcgctggtgccgcaagcgatcgtcgac
atgggccgccgcgacgccgagcggctttcggtcggcaagcgcaagggctgccataccaag
tcgcaggacgagatcaatcagttgctggtgaagcttgccggcgaaggcaagcgcgtcgtc
cggctgaagtccggcgaccctctggtctacggccgggcaggcgaggaaatggcggcactg
cgtgaagccggcatcagctacgaggtggtgccggggatcacatcggcctttgccgcggcc
gccgatttcgaactgccgctgacgctgcgcggcgtggcatcgtcgctggttttcacgacg
gggcacgatctgacaggcagcgttcttcccgattgggcgcgactggcggtttccggcgcg
acgattgccgtctatatgggccgcaccgttgcggcctccgtcgcctcgcggctcatgcag
gccggtctgccgcaggacacgaccgtcgcggtgatcgagaatgcgagccgtgccgagcgc
cgtctcctgcacggaacgctccgcgatctgccggatctcgaggcccgcacggaactggac
gggccggtcatggtgatcatcggcgaagcggttgcgggcgcgaatttcgaacggtccgag
ccgctggcggccggccgcaccaagtatagcggtgccagcaaagtttcggcgaaacgcacc
gaacagatctggaattga

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