Sinorhizobium meliloti 1021: SMc01862
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Entry
SMc01862 CDS
T00058
Symbol
murF
Name
(GenBank) Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sme
Sinorhizobium meliloti 1021
Pathway
sme00300
Lysine biosynthesis
sme00550
Peptidoglycan biosynthesis
sme01100
Metabolic pathways
sme01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sme00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMc01862 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMc01862 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMc01862 (murF)
Enzymes [BR:
sme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMc01862 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AAA_30
Motif
Other DBs
NCBI-ProteinID:
CAC46759
UniProt:
Q92NL7
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Position
complement(2349674..2351107)
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AA seq
477 aa
AA seq
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MNWLWTSSDLLAAMNGRPVGNLPEGITGISIDSRTIGDGEAFFAIRGDRVDGHDYAGIAL
ANGAALLVVSEAKLPALGRLIAPMIVVDDVLEAMIRLGCVARDRSAAKIIAVTGSVGKTT
TKEMLRHVLSPLGRVHASVASFNNHWGVPLTLARMPETTDFGVFEIGMNHAGEILPLTRM
VRPHVAVVTSIAAAHLGNFTSLDEIAAAKAEIFEGVVNGGHAVINRDSAQYDLLERAAAA
AGVSHVHSFGANPRSEFRLAEFAGGAEGSVLWAGIGGRTLEIAIGAPGRHIAENALAAIA
AATLAGADTDRVAASFATMQPEKGRGLRHRLRIGTGHLTVIDESYNANPASMRAAISLLR
DAEPAPGGRRIAVLGDMLEMGEHSAAVHAALAGPVVEAGIADVWLAGPEMAHLRDALPPE
VSVVHRDVVGDLTAYALGAVSAGDVVMVKSSKGTGCAKIVQALLDAYPQETAGAGEV
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
ttgaactggctctggacaagcagcgatcttctggccgcgatgaacggccgcccggtcgga
aacctgccggaaggtatcaccggcatttcgatcgacagccgcacgatcggcgacggcgag
gcctttttcgcgatcaggggcgatcgcgtcgacggccacgactatgccggtatcgcgctt
gcaaacggagccgcgctcctggtcgtcagcgaagcgaagctgccggcgctcgggcgcctg
atcgccccgatgatcgtcgtcgacgacgtgctggaggcgatgatccggctcggttgcgtg
gcacgcgaccgcagcgcggcgaaaatcatcgccgtcacgggatcggtgggcaagaccacc
acgaaggagatgctgaggcacgtgctgtcgcccctcggccgggtccacgcctccgtggcg
tccttcaacaatcactggggcgtgccgttgacgcttgcgcgcatgccggagacgaccgat
ttcggggtcttcgagatcgggatgaaccatgcgggcgaaattctgccgctgacacggatg
gttcgtccgcatgtggctgttgtgaccagcattgccgccgcccatctcggcaatttcacg
agcctggacgagatcgcggcggccaaggccgaaatcttcgaaggcgtggtcaatggaggt
catgcggtcatcaatcgggacagcgcgcaatacgatctcctcgaaagggcggctgccgcg
gccggggtgagccatgtccattccttcggcgcaaatccgagatcggaattccgtctggcc
gagttcgccggcggagcggaaggctcggtgctctgggccggcatcggaggcagaacgctt
gaaatcgcgatcggcgcccccgggcgccatatcgcggaaaacgccttggcggcgatcgcc
gcggcgacgctggcaggcgcggataccgaccgcgtcgccgcgtcgtttgcgaccatgcag
ccggaaaagggccgggggctgcggcatcgcctcaggatcggcaccgggcacctcaccgtg
atcgacgagagctacaacgccaatcccgcgtcgatgcgggcggcgatctcgcttcttcgc
gacgccgagccggcgcccggcgggcgacgcatcgccgttctcggcgacatgctggaaatg
ggcgagcattcggcggctgttcatgcggcgcttgcgggacccgttgtcgaggcgggtatt
gccgatgtctggctggccggacccgagatggcccatttgcgcgacgctctgccgccggag
gtatccgtcgttcatcgagatgtggtgggcgatctcacggcctacgccctcggcgcggtt
tcggccggcgacgtcgtgatggtcaagtcttcgaaaggcacgggttgcgcaaagatcgtc
caggcgcttctcgatgcctatccgcaggagacggccggagcaggggaagtatag
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