Sinorhizobium meliloti 2011: SM2011_c02546
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Entry
SM2011_c02546 CDS
T02497
Symbol
leuA2
Name
(GenBank) Putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smel
Sinorhizobium meliloti 2011
Pathway
smel00290
Valine, leucine and isoleucine biosynthesis
smel00620
Pyruvate metabolism
smel01100
Metabolic pathways
smel01110
Biosynthesis of secondary metabolites
smel01210
2-Oxocarboxylic acid metabolism
smel01230
Biosynthesis of amino acids
Module
smel_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smel00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SM2011_c02546 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SM2011_c02546 (leuA2)
Enzymes [BR:
smel01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SM2011_c02546 (leuA2)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
EF-hand_14
TRIP13_N
Motif
Other DBs
NCBI-ProteinID:
AGG73695
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All DBs
Position
1213131..1214747
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AA seq
538 aa
AA seq
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MTRERIYLFDTTLRDGQQTPGIDFSVEDKIAIASLLDQFGMDYVEGGYPGANPTDTEFFK
CRRTDKASFVAFGMTKRAGVSASNDPGLSALLSAKSDAICLVAKSWDYHVEVALGCTNEE
NLDNIRASVEAVVASGREAMVDCEHFFDGYKANSAYALACAKTAFEAGARWVVLCDTNGG
TQPPEIREIVSAVIAEGVPGANLGIHAHNDTGQAVANSLAAVEAGVRQIQGTLNGIGERC
GNANLVTLIATLALKETYSSRFETGIDAERLQELTKLAHAFDELLNRSPDPQAPYVGASA
FATKAGIHASALLKDPRTYEHVAPESVGNLRKVMVSDQGGKANFINALKRRGITVSKDDP
RLDKLISIVKEREATGYAYEGADASFALLASRILGTVPDFFRVESFRVMVERRFDANGKL
KTVSEAVVRVIVDGETMMSVAEGHGPVNALDLALRKDLGKYQSEIADLELADYKVRILNG
GTEAVTRVLIESTDRSGARWWTVGVSDNIIDASFQALMDSIVYKLLKNRDQVGSIAAE
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggaacgcatctatctcttcgacacgacgcttcgggacgggcagcagacgccc
ggcatcgacttttccgtcgaggacaagatcgcgattgcgtcgctgcttgatcaattcggc
atggattatgtcgagggcggatatcccggcgccaatcccacggatacggagttcttcaag
tgccggcgcaccgacaaggcctccttcgtcgccttcggcatgaccaagcgcgccggcgtc
tccgcctccaacgacccgggcctgagcgcgctgctgagcgccaagagcgatgcgatctgt
cttgtcgccaagagctgggattatcatgtcgaggtggcgctcggctgtacgaacgaggaa
aatctcgacaatatccgcgcttccgtggaggcggtcgtggcttccggccgcgaggcgatg
gtcgattgcgagcatttcttcgacggctacaaggcgaactccgcctatgcgctcgcctgc
gcgaaaacggctttcgaggccggcgcgcgctgggtcgtgctttgcgacacgaatggcggc
acgcagcctcccgagatccgcgagatcgtctcggccgtgattgcggagggagtgcccggt
gcaaatctcggcatccatgcgcataatgatacggggcaggcggtggccaactcgctggct
gcggtggaagccggcgttcgtcagatccagggcacgctcaacggcatcggcgaacgctgc
ggcaatgccaatctcgtgacgctgattgcgacgcttgccctgaaggaaacctattcgagc
cgtttcgagacgggaatcgatgccgagaggctccaggaactgaccaagctcgcccatgcc
ttcgacgagttgctcaaccgctctccggatccccaggccccctatgtcggcgcttcggct
tttgccaccaaggccggcattcacgcctccgcgttgctcaaggatccgaggacctacgag
catgtcgcgccggaaagcgtcggcaacctgcgcaaggtcatggtctccgatcagggaggc
aaggccaacttcatcaatgctctcaagcggcgcggcatcacggtctccaaggacgatccg
cggctcgacaagctgatctcgatcgtcaaggaacgcgaggcgacgggctatgcctatgaa
ggtgcggatgcgagcttcgcgctgctcgcgagccgcattctcggcaccgtgcccgatttt
ttccgggtggagagcttccgggtgatggtcgagcgccgcttcgatgcgaacggcaagctg
aagacggtatcggaggccgtggtcagggtgatcgtcgacggcgaaacgatgatgtcggtc
gccgaggggcatggcccggtcaacgcgctcgacctcgcgcttcgcaaggatctcggcaag
taccagtccgagatcgccgatctggaacttgccgattacaaggtgcgcatcctcaacggc
ggcaccgaggccgtcacccgcgtcctgatcgaatcgacggaccgctcaggggcgcgctgg
tggacggtcggcgtatccgacaacatcatcgacgcctcatttcaggcattgatggacagt
atcgtctacaagctgctcaaaaaccgcgatcaggtcggatcgatcgcggccgagtag
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