Sinorhizobium meliloti 2011: SM2011_c02717
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Entry
SM2011_c02717 CDS
T02497
Symbol
leuA1
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smel
Sinorhizobium meliloti 2011
Pathway
smel00290
Valine, leucine and isoleucine biosynthesis
smel00620
Pyruvate metabolism
smel01100
Metabolic pathways
smel01110
Biosynthesis of secondary metabolites
smel01210
2-Oxocarboxylic acid metabolism
smel01230
Biosynthesis of amino acids
Module
smel_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smel00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SM2011_c02717 (leuA1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SM2011_c02717 (leuA1)
Enzymes [BR:
smel01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SM2011_c02717 (leuA1)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Sigma_reg_N
Motif
Other DBs
NCBI-ProteinID:
AGG74971
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All DBs
Position
complement(2564546..2566255)
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AA seq
569 aa
AA seq
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MILKSHSIKTGMPEAAVKYQPYPQIVLPDRTWPSKAITEAPIWCSVDLRDGNQALVDPMG
HDRKARMFHLLLDMGFKEIEIGFPSASQTDYDFARWCVEEGNVSEDVSLQVLVQCRPELI
ARTFEALEGAHRPIVHFYNSTSELQRRVVFGKDVAGIKQIATDAAKMITDMAAKAGGGYR
FEYSPESFTGTELEVALEICNAVIEIVRPTADNKLIINLPSTVEMATPNIYADQIEWMCR
NLDNRENLIVSLHPHNDRGTGIAATELGLMAGADRVEGTLFGNGERTGNVDVVTLALNMF
TQGVDPKLDCSDIERIKEVYEYSNQMVIPERHPYVGELVYTAFSGSHQDAINKGMKAIKQ
ANKPTWEVPYLPIDPRDVGRSYEAIIRINSQSGKGGIAYILQEDYGINLPRNLQIEFREE
VQRITDEEGKELPSKRIHQRFIESYVEQPGARIKFVDHHTYPAGEHKGLRVVAAEITDGG
ETRQIEGKGTGPIDGFINALSIYLGIELSVADYSEHSLQHGSNAAAIAYVEVEYPGGKLF
GVGINTNIVAASLEAIVSAANRVLDVVGK
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgattttgaaatcacattccatcaagaccggcatgcccgaggcggctgtgaaatatcag
ccctatccgcagatcgtgctgccggatcgcacgtggccgtcaaaggcgatcaccgaggcg
cctatctggtgttccgtggatctgcgcgacggcaaccaggcgctcgtcgatccgatgggt
cacgaccggaaggcgcgcatgttccacctcctcctggacatgggcttcaaggagatcgag
atcggcttcccgtccgcgtcgcagacggattacgatttcgcccgctggtgcgtcgaggaa
ggcaacgtttccgaagacgtgtccctgcaggtgctggtccagtgccggccggaattgatc
gcgcggaccttcgaggcgcttgaaggtgcgcaccggccgatcgtacatttctacaattcg
acgagcgagctgcagcgccgcgtcgtcttcggcaaggacgtggccggcatcaagcagatc
gcgactgacgccgccaagatgatcaccgacatggccgcgaaagcgggcggcggttatcgc
ttcgaatactcgccggaaagcttcaccggcaccgaactcgaagtggcattggagatttgc
aacgccgtgatcgagatcgtacggccgacggcggacaacaagctcatcatcaacctgccc
tcgaccgtggagatggcgacgccgaacatctatgccgaccagatcgaatggatgtgccgc
aatctcgataatcgcgagaacctgatcgtctcgctgcatccgcacaacgatcgcggcacc
ggcattgccgccaccgagctggggctgatggcgggcgccgaccgtgtcgaggggacgctc
ttcggcaatggcgagcgcaccggcaacgtcgatgtggtgacgctggcgctcaacatgttc
acgcagggcgtcgatcccaagctcgactgctcggacatcgagcggatcaaggaagtctac
gaatattccaaccagatggtcattccggaacgccacccctatgtaggcgaactggtctac
acggccttctccggctcgcatcaggatgccatcaacaagggcatgaaggcgatcaaacag
gcgaacaagccgacctgggaggtaccctatctgccgatcgatccgcgcgatgtcggacgc
agctacgaagcgatcatccgcatcaactcgcaatcgggcaagggcggcatcgcctatatc
ctgcaggaggactacggtatcaatctgccgcgcaatctgcagatcgagttccgtgaggaa
gtccagcgcattaccgacgaggaaggcaaggagctgccctcgaagcgcatccatcagcgc
ttcatcgaaagctatgtcgagcagccgggcgcgcgcatcaagttcgtcgaccatcacacc
tacccggcaggcgagcacaagggcctgcgcgtcgttgccgccgaaatcacggatggcggc
gagaccaggcagatcgagggcaagggcacgggcccgatcgacggcttcatcaatgcgctg
tcgatctatctcggcatcgaactctcggtggcggattactccgagcattcgctgcagcat
ggttcgaacgccgctgcgatcgcctatgtcgaggtcgagtatccgggcggcaagctcttc
ggcgtcggtatcaacaccaatatcgtggccgcctcactggaggcgatcgtctcggctgcc
aaccgcgtgctggacgtggtggggaagtga
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