Streptococcus merionis: SAMEA4412692_0865
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Entry
SAMEA4412692_0865 CDS
T07119
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smen
Streptococcus merionis
Pathway
smen00300
Lysine biosynthesis
smen00550
Peptidoglycan biosynthesis
smen01100
Metabolic pathways
smen01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smen00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SAMEA4412692_0865 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SAMEA4412692_0865 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SAMEA4412692_0865 (murF)
Enzymes [BR:
smen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SAMEA4412692_0865 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RecA-like_ORC2
Motif
Other DBs
NCBI-ProteinID:
SNU88024
UniProt:
A0A239STF3
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All DBs
Position
1:complement(929615..930958)
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AA seq
447 aa
AA seq
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MKLTLHEIGRIVSAKNDYSQYEDTCISAIEFDSRKIKTGDLFLPLKGARDGHDFIEIAFE
NGAIATFSERPIEKPHLLVEDCLAAFQALAQYYIEKTGVDVIAVTGSNGKTTTKDMLHDI
LTTTYQTYKTQGNYNNEIGLPYTVLHMPDETEKLVLEMGQDHLGDIKLLSEIAKPAMAIV
TLVGEAHLEFFGNREKIAEGKLQIAEGMPDNGLLLVPNDPIIEPYLPTKQEILTFGENGD
LFLTDLVEEKQSLTFRTNFLESDVRLPVPGKYNAINAMVASYVAMRSGVKEADILAALAK
LNLTRNRTEWKTAQNGAEILSDVYNANPTAMRLILETFSAIAKNPSGRKIVVLADMKELG
PTSAQLHAQMKESISEKIDLIYLYGPEMKALAIAMAGDTRVRYYADYSEFEALKQQLLDE
VQPADQVLLKGSNSMNLGQLVAALTEE
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atgaagttaactttacatgaaataggccgtatcgtttcagctaaaaatgattatagtcaa
tatgaggatacgtgcatttcagctattgaatttgatagtcgtaagattaaaacaggggac
ctttttttgccccttaagggtgcgcgcgatggtcatgattttattgagattgcctttgaa
aacggagctattgcaactttttcagaacgaccaatagagaaacctcatcttttagttgag
gattgcttagcggcctttcaggctttagcacagtattacattgagaagacaggggtagat
gtgattgcggtcactggatcaaatgggaagacaacgaccaaagacatgcttcatgatatt
ctgacaacgacctatcagacttacaagacccaaggcaattacaataatgaaattggactg
ccctacactgttcttcacatgcctgatgagacggagaagttggtcttagagatggggcaa
gatcatctaggggatatcaaactgctctctgaaatcgccaagccagctatggctattgtg
accctagttggcgaagcccatttagagtttttcggcaatcgtgaaaaaattgctgagggc
aagcttcaaattgctgaggggatgccagataacggcctgctcttggtgcctaatgatccc
atcattgagccttatttgcctaccaagcaagaaattctgactttcggtgaaaatggtgat
ctcttcttgactgatttggtggaagaaaagcagagcttaacctttagaactaacttttta
gaaagtgacgttagactgcccgttcccggcaagtataacgcgataaatgctatggtcgcg
agttatgtagccatgcgaagtggtgtaaaggaagcagatattctggctgcgctagctaaa
ctcaatttgactcgtaaccgcaccgagtggaagactgcgcaaaatggcgctgaaatcctt
tcagatgtttacaatgccaacccaacagccatgcgactgattttggaaactttttcagct
attgctaagaatcctagcggacggaaaatcgttgttctggcagatatgaaagaattgggc
ccgacctcggcgcagctccatgcgcaaatgaaagagagcatcagtgaaaagattgatttg
atttatctctatggtccagaaatgaaggcattagcgatagctatggcaggcgatacgcgt
gtgcgatactatgctgactattcagaattcgaagcgctcaaacaacagttgctagacgaa
gtccagccagctgatcaggtcttgctcaaggggtcaaattccatgaatctgggtcaactt
gtggctgcgctgacagaagaataa
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