Silurus meridionalis (southern catfish): 124389374 Help Entry 124389374         CDS       T08004                                  Symbol pkd1b Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism smeo  Silurus meridionalis (southern catfish) Brite KEGG Orthology (KO) [BR:smeo00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:smeo03037]     124389374 (pkd1b)    04812 Cytoskeleton proteins [BR:smeo04812]     124389374 (pkd1b)    04040 Ion channels [BR:smeo04040]     124389374 (pkd1b)    04091 Lectins [BR:smeo04091]     124389374 (pkd1b) Cilium and associated proteins [BR:smeo03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    124389374 (pkd1b) Cytoskeleton proteins [BR:smeo04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     124389374 (pkd1b) Ion channels [BR:smeo04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    124389374 (pkd1b) Lectins [BR:smeo04091]  C-Type lectins   Others    124389374 (pkd1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PKD_channel PLAT Polycystin_dom Lectin_C Ion_trans GPS DUF2436 Motif Other DBs NCBI-GeneID:  124389374 NCBI-ProteinID:  XP_046710707 LinkDB All DBs Position 7:24410443..24457893 Genome browser AA seq 4017 aa AA seqDB search MDLLHLTLVFIICAVTSCSRDESCCPKGAQIDRDRLHCYWMSASALSWQAARMECQKTDR GDLAVVDQPGVQKFIEDSFLLETPELVWLRNGLLRPLGDPTHGVEERGTCSQMSLGTGYW TSSPCDQKHRFICGKEIPASLPLDSYVIGVALMSGVYTHSQLHPLPSPPDLDQQRAEMML FPGIWVSHGGQVLSVELVVQPSQQLTAAKVQILRPYCSPSHHLVPPGCRSILNPFTCCSV KPLCNTTGGCSSGQYWCHLVESCLPVTSPCSPYHSSANGHVFTLPPRYTALTPFYHMVAD IALEIPSASEPVHIDVRFKGKKIPVFPDDILAIQHSRKSGEFLHCTSGSDSVWRQSYISI PGPEWGGWVDVALSSLTEGGHWLDNMSCDLRLIYQDPGHLNGVGKVTQNEPSTEVSMPGN ILIPAQTPVTGMHILYPVLDKDNRIHLAVNVQTLFIIKILSGSNATSSWSGLVSRTEVPF LKSCPEEIPEMIRVCKRDSADTWFSYAPIMATSQGEHTLDVTASNQLNSQRLSVKIQAHV IITGLRIQPQGFHRVLVNIPQMFTTAVATGSSVKYTWVIDDLIQFAHTGDAYSITFNKPA EYTLKVNAENPVSTQYMEVKLTADVMTPLADLALLSETVAVAVNTSSVFTVQVKLDVSIG VTIRWDFGDHSSCVDHTFIAPLEKNNVPLDQTATQVYLQDAAHHIYTTPGDYTLRIQAQN KYDFIQTAVLHKVRSPLTKLLVISKPASPKINQTILFEASSQPSSHGIVYTWNFGDGFPE VEGPHKTIRHAFKKAGVFNVSVISDNTLSKLNSWMVVEVFEMISGVHLGSNSPSELNSII KISGGVSTGTSLRWTFDLGDGTVFKDLKKNSISYVYRSVGNYTVQAMVWNEVSSEREAID VEIYQLAVLGILPLECVVSGKEVTLQALVRGNVSHLAFYWRFGDSKDVSVKNGIATVAHT FSGTGNYLIGVTIQSQAGSADYQSNLCVENSITDLNLHSSLNVAALGKEICFDVSVLPAG GENYQFHWYNSSFCDCPVNGTSHHCFIFFQEGKHEITVMAQNQVSKKTASTTILVQRPLS VRHNGELDVLTVNQTYYFWTEPSKNNAAIEWDFGDGSLKSRGQNVSHNFTSAGQYHISAS VLNAVSKEIIKVDVQVQVPISNIRIHTNRPFAEAGQEAVFTISSDVMENVKFYWMIDSMT FSELGTSEYRYVFPKAGIFQIRVTAQNPVSKVETSLTIEVVERIQGVRIMSLKSASYIPT NETVTLVASVSRGTSLTYQWLANQAEVNDLVGVGEHFQFYTIHPGNVSVRLIVANVLGKV HSDFSLRAVERVSEVNIPLSNVVAKGKPVSIAVEIKTGTDLQYTWFLDTNLSSVTTDVPF VLHVFNTVGVFKLRVSVGNVLGSVNATKQLMIQEPVSEIDFDINGQSHPYFVSSNSPLTF HGSARKGSDVHWEWTARSVEGSAVVLDKNQIISYLFMDAGDHRVTLNVSNEISWQSVSHV VTVQDAIRGFSLRASDVIVCENDPVTFTPSITQGSGVSFLLEFPEGNTSLEDQEDFTTSS IPLGNHTIKAIAKNLVSILSVNITIRVVQGLKGLHLVDCCSSVLEASKPVHFKASVNSGS KVIYRWNFHLDGLRTSQQTGQSVLYSPFSNGTLTVMVEAKTDFCSQSITETALVQQPVKN VTLSILSEGPFVNHSVTFFALVDGGSDLAIKWSFGDEIRLTKSNKEVYKYKVDGKFMVQV TVFNNISQVSAHFPVLVRKLKCIQPRVALVQEQARILKSQPNYFEASVDLNGCTSYKTNY LWEIFRDPDCTERKVFLHASVDVTKPLLAISKNTLEVGDYCVKFSTWFEGTPLRHHKTGG FSVGNSPLVPLIKGGSIKVWSNQKDLVLDGSESFDPDATIPEVDLLEFQWNIIMEQNTSS TQYPASFINNYSIHCNESKLILPRHLLEPERVYKFTLTIHKHARLPVSTVQHVQVLDTEV LPVTVKCVSCRLVFSSAVSYSHPVALAGACSLCNGTLQYKWTAKTTKGETLLLNEVTTST GHGSSDLVIRPNVLKPGFEYIFSLNVSQPATGLWGSASFALTQNRPPEGGMCTLSPEDSV QLLQNVVSFNCSGWVDEDNISAQMIYALQIAQCQSTETECPLITLYRGIRSAFGTLVPMG STRPGHNASILTVMVTVEDNMGAKITAVKRNLVVMVPVRDQDMMEWLKNKSQEELWDLVK QGNPQDVISYAMAMSSQLNQIQATSMQELKDKVQMRGNVTQALASLSVSSLQDASQISSA LAHSTAVTSEMQCGDCNSQVVEAVGKMIGVIREQTRQGDLTPIDTGRNILNVLSTSMTVK NPVDALGSLLHGPKHHDTAVSALYQVGQLMRSLMWSRMPGEEALLLQSPRINATGKRGDP ASDLLCTDPSSSCQFYIPSNLSSRLRAENQEVVQIVLVLESEEIPFVSPAEPPISTKLTA MEFLTPHGSPIPVSNLTEESAIRVTLHNKKMEVSGRVNVTLRSEGSVNFMVRAVETEPNA GLFITFNFSLSEGSSMPGSGKVTIIISDEQTVHQSQHTHVKELILASFTTSVEETIFLEP VLNGSAKDLYVTLRSSTGVDLCVSVCVFSSLCQFFDMERRRWSTGGLSVLSTSSPDTAHC LTEHLTLFGASLFIHPDAIVFLAPSDVPRRNMVVGIVCGILLLIHLLVGLIAHKLDHLES LRLSCVPLCGQTGRYRYRVLVKTGWYRGAGTSAHVGISLYGLNKSGSRHLQREGAFQRNG LDDFQVETDVNLGEIWKICIWHDNTGLEPPWYLQHVTVWDMQTDNMFFFLVDDWLSVENE RNSGLVQKVVLATCPPELQQFRRIWRAQLLFGLQDHHLWLSLWERPAHSTFSRAQRVTCC ALVLHLYLAAGAVWYGLATSSSRGPVSDQMPMTPEIILVGMTIAVVMFPLQSLLTFLFRK TKSKVAMELCLPPSPMSDIVEMDVYLSHPVISCASFMSMPTAQESSTHTESSFESLESPK LESEFWTRSHFGSESPCSSGVEQWTSSDSIFGLAELMGPTRLLKRKRALLQLRLNSPDRS TPEQSSSSYLKKEQSTFFGELPPASADPFLSSASSSGPSGSDSGRYSPNETALSDTLESS SSEWMDLSVEKLDCDEGLYKTHCSMSMCSVASTFLPSLPPDSFSTTSITHIGVSRSAPGL MLPSWVLAVTYLLVAVLLGTCLVLVGLYGSTFSNSVLLMWLTSVLSAFFTSLLILEPLTI CVRAMYLAGVVKPVDPEVEDRLAQETVVMRMEKDQDVDVRPLCGYGLLHAKEEARKVRIL RNLMKNCLIYLLFLLVVLLMNYQDNIQETNSRLLHSAVKRSIISALPGQPNLTALSGWTE VWQWMDKILTSHLHKNPSLSLIGLARIQRVTSPNYCEEDPGDTLKHVQTLMRQRHQSNST TSFFTWPWSTAQSCVLTEADEMLLGNSSFYTTHILSDLKQAQWITTETQAMLVEFTQYHR GTGIFLPVSILLEKTQTQRILSTVSIQPFHIPGSFSGLDLSIGITALLLIFSLCFLSAEV WRIFRERAQYLTQGWHLFQLLVALLSFSAASLRFCFLSMAAECLSDHVSQPETFTGFHNI AALAKSSSQLSAVLLMFLVPQMAGSLQFVRRWVIFVRVLHQACSEICGITLLFVLLLLLF SHTGCLLFSASVEGFRTVRQASESLLCLLRNRFVLRQLSEEHPVLGPIFCLAVFGLGFWL LGRLCGAVLLQRYKNIQAEMYRPSMEPQDYEMVEFLIKRLKLWMGLSKIKEFRHRVKFEG MESPPSRSSQFSSISPPVSPPRPRLVSASSQVSESSTISESHEVQQYLDRLLPSVDNLLA SFDRVNQLTNDILNIEEQLQEILSRIVQKRRKHNQPKPQMSPATKLARPSQTSLPMSLKA LRPSNDGIPQAPSNRRATHSESSLMAPSAHLTNYPRVAGTQKSQTVDQEIRGFPRRRAWH SGSCHSADTIQRFAKSQSPGAIPVRPHSEESDWTAASGGMPIKKKAWHTDSFEIEKG NT seq 12054 nt NT seq  +upstreamnt  +downstreamnt atggatctcctccacctgactctagtcttcattatctgtgctgtgactagctgctcccgt gatgaaagttgttgcccaaaaggagctcagatcgatcgagaccgattgcactgttactgg atgtcagcatctgcactgagctggcaagcagcaaggatggaatgtcagaaaacagacaga ggagatctcgccgtggtggaccaacccggcgttcagaagtttatagaagattcatttctg ctagaaacccctgaattggtttggctaagaaatggactcttacgtcctttgggtgacccg actcatggtgtggaagagcgaggaacttgttctcagatgtctcttggtacgggatactgg acaagcagcccatgtgaccaaaagcaccgctttatctgtgggaaagagataccagcgtct ttgccgttggacagctatgtcattggagtggcgttaatgtcgggcgtatacacacactcc cagttgcacccactgccttcaccaccagacttagaccaacagagagctgagatgatgctg ttcccaggaatatgggtgagtcatggaggccaggtgctttctgtagaactggtggttcag cccagtcagcagctcaccgcagctaaagttcagattttacgaccgtactgcagcccgagc catcacttagtgcccccaggctgccgctctatcctcaacccgttcacctgctgctcggtg aaacctctgtgtaacaccaccgggggttgttcaagtgggcagtactggtgccatctggtg gaaagctgcctgccagtcaccagcccttgcagcccttatcactcatctgctaatggacac gtcttcactctgccacctcgctacactgcattgactcctttctaccacatggtggcagac atagcattggaaataccttcagcttctgagccggtccacatcgatgtcaggtttaaagga aaaaaaatcccggtgtttcctgatgatattcttgccattcagcacagtagaaaatctgga gagttcctgcactgcaccagcggctcggactctgtctggcgccaaagctacatctccatt cctggacctgagtggggcggctgggtggacgtcgcattgtcctctctgacagagggaggc cactggcttgacaacatgtcttgcgacctgcgtctgatctatcaagaccctggacatctt aatggtgttgggaaagtcacccagaacgaacccagtacagaagtgagcatgcctggcaac attctgatccccgctcagaccccagtgaccggaatgcacattctctatcctgtactggac aaagataaccgaatacatttagcagtaaatgtccagactctctttattatcaagattctt tcaggaagtaacgcgacaagctcatggtctggcctcgtgtccaggacagaggttccattc ctaaagtcctgtccagaagagatccctgaaatgatcagagtttgtaaaagggattcggct gatacatggttctcttatgcacccatcatggctactagtcaaggggaacacactctggat gttacagcgtcaaaccagctgaactcacagaggcttagtgtgaagattcaagctcacgtt attatcacaggactgagaatacaaccgcaaggatttcatagagttctagtgaacatacct cagatgttcaccacagcagtagccactggatcatctgtgaagtacacctgggtcattgat gatctcatccagtttgctcacactggagatgcgtacagcatcactttcaacaaacctgca gagtacacgctcaaagtaaatgcagagaatcctgtcagcactcagtacatggaggtcaaa ctcacggccgatgtgatgaccccattagccgacctcgcattactctccgagacggtggct gttgctgtaaacacctcaagcgtcttcaccgttcaagtgaaactggatgtttctatcggt gtcacaataaggtgggattttggtgaccattcgagctgcgttgatcatacgttcatcgct ccgttagaaaaaaacaatgtacctttggatcagactgcgacacaggtttacctgcaggac gctgcacatcatatctacacaacacctggtgactacacactgaggatacaagcccaaaat aaatacgattttatccaaactgctgtgctacataaagtaagatctccgctgaccaaactg ctagtcatatcaaagcctgcttcccctaaaatcaaccaaactattctttttgaagcctca tcacagccgtcttcacatggaatagtgtacacgtggaattttggagatggctttccagag gttgaaggacctcacaagacaatcaggcacgctttcaagaaagccggtgtcttcaatgtt tctgtgatttccgacaacaccctttcaaagctgaattcctggatggtagtagaagttttt gaaatgatctccggtgtccacctggggtctaatagcccaagtgaacttaattcaatcatt aaaatcagtggaggtgtatctacaggtaccagtctcaggtggaccttcgatcttggtgat gggactgtgtttaaagaccttaagaaaaactcgatctcttacgtttataggtctgtagga aactataccgtccaagctatggtttggaatgaggtgagtagcgagagagaggctattgat gtagaaatttatcaacttgctgttttgggaatcctgcccctggagtgcgtcgtgagtgga aaggaagtgactcttcaagcgcttgtgagagggaatgtttctcatctagccttttattgg cgtttcggagatagtaaagacgtgtccgtgaagaacggaatcgcaactgttgctcatacg ttctcaggtactgggaattacctcattggcgtgaccattcagagccaagcaggatctgca gactatcagtcgaatctatgtgttgagaactcgattacagatttgaaccttcactcttct ttaaatgttgcagcattgggcaaagagatatgttttgatgtgtcagtgcttccagccggt ggggaaaactaccaatttcactggtataacagctctttctgcgattgtcctgtcaacggg acgtcacatcactgcttcattttttttcaagaaggcaagcatgagattacggtaatggca cagaaccaggtcagcaagaaaactgcctcgacaaccattttagtccaaagacctttatct gtacgacacaatggggaattagacgtgttaaccgtgaatcagacgtattacttttggact gagcctagcaagaataatgctgctatcgaatgggactttggtgatggttcgttgaagagc agaggccaaaatgtgtcacacaatttcacatcagctggtcagtatcacatcagtgcttca gttctcaatgcagttagcaaagagatcataaaggtcgatgtacaagtccaggttcctata tctaatataagaattcataccaaccggccatttgctgaagcaggacaagaagcagttttc acaatttcaagcgatgtcatggagaatgttaaattctactggatgatagactccatgact ttttcagaacttggaacatcagagtacagatatgtctttcctaaagcaggcatctttcaa atccgtgtcacagcacagaatccagtcagtaaagtcgaaacctcattaacaatcgaggtg gtagagagaatacaaggtgtccgaattatgagcctgaaatctgcaagctatatcccaaca aacgagactgttactctggttgcttctgtaagccgtggtactagcttgacatatcagtgg ttagctaatcaagctgaagttaatgacctagtcggtgttggggaacattttcagttctat acaatccacccgggtaatgtgtctgtcaggcttatagttgctaatgttcttggtaaagtg catagcgatttttctctgagggcagttgagcgtgtatctgaggtaaatatcccattatcg aatgtggtagcaaaaggaaaacccgttagcatagcagtggagattaaaaccgggacggat cttcagtatacttggtttttggacacaaatttatcatctgtgacaacagacgtacctttt gtccttcatgtttttaatactgttggggtttttaagctaagagtgtcagtaggaaatgtt ttgggctcagtcaatgccactaaacaactcatgatacaggaacccgtttcagagatcgat tttgacataaatggacaatcacatccctactttgtttcatcaaacagtcccttgacgttc catggatccgctcgaaaaggaagcgatgtacactgggagtggacggccaggtctgtggaa ggaagtgcagttgttttagataaaaatcaaataattagctatttgtttatggatgcagga gatcacagagtaaccctaaacgtctcaaatgagattagctggcagtctgtgtcgcatgtt gtaacggtgcaagatgccattcgaggtttcagtctaagagccagtgatgtcatcgtctgt gagaatgacccagtcacttttacaccatctatcactcagggaagcggagtttcattcctt ctggaatttccagaaggcaatacgtctctggaagatcaagaggattttactacctcatct attcctcttggcaatcacaccattaaagcaattgctaagaatcttgttagcattttatca gtaaacatcaccataagggtggtacaaggacttaaaggtcttcacttggttgattgctgc tcttctgttttggaagcctcaaaacctgtccatttcaaagcatccgtaaattcaggatct aaggtcatttacagatggaatttccacttagatggcttgagaacctcacaacagactggt caaagtgtcctgtattctccatttagcaacggaactctgactgtgatggtagaagcgaag actgacttctgttcccagtccatcacagagacagcactagttcagcagccggtgaaaaac gtgacactttccatcttatctgagggaccttttgtgaatcacagcgtcacttttttcgcc ctcgtcgatggtggcagtgacctcgcgatcaagtggagctttggtgacgagatccgactt acaaaatctaacaaggaagtctacaaatataaggttgatggcaaatttatggtccaggta actgttttcaataacatcagccaagtttctgcacattttccggttctggtaaggaaactg aaatgcatccagccacgcgtcgccctcgtccaagaacaggcaagaatcctgaaatctcag ccaaattatttcgaagcaagcgtggatctaaacggttgcacttcttacaagacaaactac ctctgggagatctttagagacccagattgcactgaaaggaaagtctttttacatgcatcg gtagatgttaccaaaccgcttctggctatttcaaagaacacactagaagttggagactac tgcgtgaagttttctacttggtttgaaggaacgccattacggcatcacaagactggcggg ttttctgtagggaacagtccattggttcctctgattaaaggtggctcaattaaagtttgg tcaaaccagaaagaccttgtgctggatggaagtgagtcatttgatcctgacgctacgatt ccagaggttgatctgttggaatttcaatggaatattattatggagcagaacaccagttca actcaatatccagcatcctttatcaacaattattccatacactgtaacgaaagtaagctt attctgcccagacatctactagagccagagagagtatacaagttcacactgacaattcac aagcatgcgagattacctgtctctactgtccagcatgttcaagtgcttgacacagaagtg ctacccgtcaccgtgaagtgtgtatcctgcagattggtgttttcttctgctgtcagttac agccatcctgtcgctttagccggagcttgttctctgtgcaatggcactcttcagtataaa tggactgctaaaaccacaaagggagaaactttacttctaaatgaagtcacaacttcgaca ggacatggatcttcagatcttgtcatcagacccaatgtgctaaaacctggatttgagtat atattcagccttaatgtatctcaaccagctacaggattgtggggatcagcgagctttgct ttaacccaaaatcgcccacctgaggggggcatgtgcacattgtctccagaggattcagtt caacttctgcaaaatgtagtttcgtttaactgctcaggctgggtggatgaagacaatatc tccgctcagatgatctacgctcttcagatagcacaatgccaaagcacagaaacagagtgt cctttgataaccctataccgaggcatacggagtgcatttggtactctggtacccatgggc agtacaagaccaggccacaatgcctccattctcactgtaatggtgactgtcgaggacaac atgggagccaaaatcactgctgtaaaaaggaatctggtagtcatggtaccggtcagggac caagacatgatggaatggttgaagaacaagagtcaggaggaactgtgggatttggtgaaa caagggaaccctcaggatgttatatcatatgccatggcgatgagcagccagctcaatcag atacaagcaaccagcatgcaggagttaaaagacaaagtccagatgcgaggcaatgtgacc caggccttggcttctctctcggtgtcctcgctccaggatgcatcacagatcagctcggct ttggctcattccactgccgttacgtctgagatgcagtgtggagactgtaactcgcaagtt gtggaggccgtggggaagatgatcggtgtaatcagagagcaaaccagacaaggagatctc actcctatagacactggaaggaatattctcaatgttttaagtacctcgatgactgtaaag aatccggtagatgctttaggatcgctcttgcatggccccaaacaccacgacactgcagta tcggccttataccaggttggacagctgatgcgtagcctaatgtggtcacggatgcctggc gaggaagctcttctcctccaaagtccacgaatcaatgcaacaggcaaacgcggagacccc gcttcagacctcctgtgtacagacccatccagttcatgccagttttacatcccttcgaat ctgagctcacgactgagggccgaaaaccaggaggtggttcagatcgttctggttctggag agcgaggagatcccattcgtgtcccctgcagagccaccgatttctactaaactaaccgca atggagttcctcacaccgcatggttcgccaatccctgtctcgaacctgacagaagaaagt gctatacgtgtaactctacataacaagaagatggaggtttcgggaagggtaaatgtcacc ctgcgatcggaaggaagcgtgaactttatggtcagagctgttgagacagagccgaacgct gggctctttatcaccttcaacttcagcttgagtgaaggaagcagtatgccaggctctgga aaagtcaccataattatatcagatgagcaaaccgtccaccagtcccaacacactcatgtt aaagagctcattctcgcctccttcactacttcagtggaggaaacgatcttcctcgaacca gtcttaaacggctccgctaaggacctgtacgtgactttaaggagcagcacaggcgtggac ttgtgtgtctcggtgtgtgtgttcagctctctctgccagttcttcgacatggaacggaga cgctggagcacaggtggactgagcgtgctcagtacgagcagcccggatactgctcactgc ctcactgagcatctcacacttttcggagcgagtctgtttattcacccggacgccattgtt tttctcgcaccatcagatgtaccgagaagaaacatggtagtagggatagtatgtggtatt ctcctcctgattcatctactggttggtctcattgcccacaaactagaccatctggagagc cttcgtctgagctgtgtcccactttgtggccaaacgggacgctaccgttatcgggtgctg gtcaaaactggctggtacagaggggccggaacctctgctcatgtaggcattagtctgtat ggtcttaacaaaagcggttcacgccacctacaaagagaaggagcctttcaaaggaacggt ctagacgactttcaggtagaaaccgatgtcaatttaggcgaaatctggaaaatatgcatc tggcatgacaacacaggtctggagcccccgtggtatcttcagcatgtgacagtttgggac atgcagacggataacatgttcttcttcctggtggatgactggctgtctgtggagaatgaa aggaactctggtttggttcagaaagtcgtgctggctacgtgccccccggagctgcagcag ttcagaaggatttggcgtgcccagcttctgttcggcctgcaggatcatcacctctggctg tctctttgggaacgtccagctcacagcacttttagccgagcccagagagtgacctgctgc gctctagtgctacacctttacctggcagcaggggcggtgtggtatggcttagcaacctca agcagcagaggtccagtgtctgaccagatgccaatgaccccagagatcatcctggttgga atgactattgctgttgtgatgtttcctctccaatctctcctcaccttcctgttcaggaag accaagagcaaggtcgccatggagctctgccttcctccttcccccatgtctgatatcgta gagatggatgtgtacctcagccacccagttatctcttgtgcttcctttatgtccatgcct acagcccaggagtcttcaacacacacagaatcttcctttgagtccttggagagcccgaaa ctggagtcggaattttggaccagatcacactttgggagtgaaagtccttgctctagcgga gttgagcagtggacatccagcgacagtatttttggtcttgctgagttgatgggacccaca cggctgctgaagagaaaaagagctcttcttcagttgcgactgaattctccagatcgttca acccccgaacagagcagttcttcatatctgaagaaagagcagtcgacgttctttggtgaa ttgccgcctgcttctgcagatcctttcctatccagtgcttcttcatcagggccaagtgga tccgatagcggccgatattcacccaatgaaactgctttatctgatacactggagagttcc tctagtgagtggatggacttgagcgtggagaagttggattgcgatgaaggtctttataaa acccactgctccatgtccatgtgtagtgtggccagtacttttctccccagtcttccccca gactccttcagcaccacctctatcacacacataggtgtgtctcgcagtgcaccaggtctg atgcttccatcttgggtgttggctgtgacttatcttcttgtggctgtgctcttgggaaca tgtctggtattggtgggcttgtacgggagcactttctccaactcggtgctcctcatgtgg ctcacatcagttctgtcagccttcttcacatcacttttgatcctggagcctcttacgata tgtgttcgggctatgtatcttgccggtgtggtaaaacctgtagacccagaggtggaggat cggttggctcaggagaccgtagtgatgaggatggagaaggatcaagatgtcgatgtgcgt cctctttgtggttacggcttgctgcacgctaaagaagaggctcggaaagtacgaattctt aggaatctcatgaagaactgcctgatctacttgctgttcctcttagtggttcttctgatg aactatcaggacaatatccaggagacgaacagcagattgcttcactctgcagtcaaacgg tcgatcatctcagctttgccaggacaacctaacctcacagcattatcagggtggacagaa gtatggcagtggatggacaaaattttaacatcccacctccacaaaaatccctccctctcc ctgattggtcttgcacgaatacaaagagtgacatcaccgaactattgtgaagaggatccc ggagacacactgaagcatgtccagacattgatgagacaaagacatcaaagcaacagtact acctccttcttcacctggccatggtccacagcacagtcatgtgtcctcactgaggcagac gaaatgttgctcggaaacagcagtttctacaccactcacatcctctcagacctgaaacaa gcgcagtggatcaccacagagacccaggccatgctagttgagttcactcagtaccacagg gggactgggatattcctgcctgtttccattctgctggagaaaacgcagactcagcggatt ctctccactgtctccatccagcctttccatatcccagggtccttctctggacttgactta agcatcggcattacggctctactgctgatattctctttgtgtttcctgagtgctgaggtt tggaggatattcagggagcgagctcagtacctcacccagggctggcatttattccagctc ttggtggctttactgtccttctcagcagcttcactgcgcttttgtttcttgtccatggct gctgagtgcctttctgaccacgtctctcagcctgagaccttcactggatttcacaacatc gctgctttggctaagagttcctcgcagctctcggctgtgttactgatgtttctggttcca cagatggccggttctctgcaattcgtaagaagatgggtgatttttgtcagggttctccat caggcatgctctgaaatctgtggcataaccctcctgtttgtgcttctgctgcttctcttt tcccacacaggatgcttgcttttttcggcttcagtggaaggttttaggactgtaaggcaa gctagtgagtccttgttgtgcttgttgagaaatcgattcgttttaaggcagctatctgag gagcatccagtgcttgggcccatattctgtctcgctgtgtttggtctggggttctggctc cttgggcgtctatgtggagccgtattactccagaggtacaagaatatccaagcagaaatg taccggccatccatggaacctcaggattacgagatggtcgagtttcttatcaagaggctc aagctatggatggggctgagcaagataaaagagttcaggcaccgtgtaaagtttgagggc atggagtcaccgccttctagatcgtcccagttctccagtatctccccacctgtaagtcct ccaaggcctcgtctagtgtctgcgtcctctcaggtctcagagtcttccactatctcagag agccatgaggtccagcaataccttgatcgcttgctgccctctgtggacaatcttcttgcc agttttgaccgtgtcaatcaactgacaaatgacatcttgaacattgaggagcagcttcag gaaatcctaagcagaattgtccaaaaaagaaggaagcacaatcagccaaaaccacagatg tctccagccacaaaactggccagacctagccaaacttcccttccaatgtcactgaaggct ctccggccttccaatgatggtatcccccaagccccctctaatcgccgtgctacccactct gagtcatctctgatggcaccttctgctcacctcacaaattatccacgagtagcaggaacg cagaaatctcagacagtagaccaagaaattagaggtttccctagacggagagcttggcac tcaggatcttgtcactctgcagatactattcaaaggtttgctaagtctcaaagccctgga gccattcctgtaagacctcacagtgaagaaagtgattggacagcagcaagtgggggcatg ccaattaaaaagaaagcctggcacactgattcttttgaaatagaaaagggctag

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