Silurus meridionalis (southern catfish): 124399856
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Entry
124399856 CDS
T08004
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
smeo
Silurus meridionalis (southern catfish)
Pathway
smeo00270
Cysteine and methionine metabolism
smeo00480
Glutathione metabolism
smeo01100
Metabolic pathways
smeo01240
Biosynthesis of cofactors
smeo04216
Ferroptosis
Module
smeo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
smeo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
124399856 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
124399856 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
124399856 (gclc)
Enzymes [BR:
smeo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
124399856 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
124399856
NCBI-ProteinID:
XP_046727079
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Position
2:33789558..33799042
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AA seq
626 aa
AA seq
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MGLLTQGSPLNWSETKKYADHVRKHGIVQFLNIYNKVKDRQKDVLKWGDEVEYMLVELDE
KNEKACLVLNGNEVLETLQEKGENANPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREGCSVLNKDETLCTITSFPRLGCPGFTKPEQKPTPVEKGASKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVAINVPIFKDQNTPNPFVETFPEDDGEAASAALSDHIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATFCPIMMALSAASPFYRGYMSDIDCRWGV
ISASVDDRTREERGLEPLKNNKFRIHKSRYDSIDSYLSFCGEKYNDIELTKDDEIYNQLL
DAGIDKLLAQHIAHLFIRDPLSLFLEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFIVLLTRVILSYKLDFLIPLSKVDDNMKVAQKRNAV
QESMFYFKKDIYKGCNPLFESKNGVENDEDQEEYTLMSIDTIINGKEGVFQGLVPILNCY
LENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKKDSVITDKINYDL
LRKCDRIAKGEEQCPELIGEPVKRGN
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgacacaaggctccccgctgaactggagcgagacgaagaagtacgccgac
catgtgaggaaacacggcatcgttcagtttcttaacatctacaacaaggtcaaagaccgg
cagaaggacgtgctcaaatggggtgatgaggtggagtacatgttggtagaactggatgaa
aaaaatgaaaaggcttgtcttgttctgaatggaaatgaagtgttggaaacgttgcaagaa
aagggggaaaatgccaaccctaaccatccaaccctgtggagaccagagtatggcagctac
atgattgagggcacgccggggcagccttatggtggaacgatgtcagagttcaacaccgta
gaggacaacatgggtaaacggaggagggagggctgctccgtgctcaacaaagacgagact
ctctgcaccatcacgtcattccctcggttgggttgtccaggtttcacaaagccagaacaa
aagccaactcctgttgaaaaaggagcaagcaagtctctcttcttccccgatgaagcaatc
aacaggcatccccgcttcagcactttgaccaggaacattcgtcacagaaggggggagaag
gtggccatcaacgtaccgatctttaaagatcaaaacacaccaaatccatttgtggagacg
tttcctgaggacgacggggaggcggcgagcgcagccctctctgaccacatctacatggac
gccatgggctttggaatgggaaactgctgtctgcaggtcacatttcaagcttgcagcatc
agtgaggctcgatacctctatgatcagctggccacattctgccccataatgatggccctc
agtgctgcttctcctttctatcgtggctacatgtcggatatcgactgtcgctggggcgtt
atctcagcctcggtggacgacagaactcgggaagaacgagggctggagcctttaaaaaac
aacaagttcaggatccacaagtcaagatacgattccatcgacagctacctttctttttgt
ggggaaaaatacaacgatatagaattgacgaaagacgatgagatctacaatcagctcctg
gacgcgggtattgacaaactattggcccagcacatcgcacacctttttattcgtgaccca
ctttcactgtttctggagaagattcatttggatgatgagaacgaatcggatcactttgag
aatcttcagtcaactaactggcagaccatgagattcaaaccacctcctccaaattctgac
ataggatggagagtcgagtttcggcccatggaggttcagttaaccgactttgagaacgct
gcatatgttgtgttcattgtactcctcacacgagtgatcctttcctacaagttagacttt
ctcattcctttgtcaaaggttgatgacaacatgaaagtcgcccagaaacgaaatgccgtg
caagaaagcatgttttatttcaagaaggacatctataaaggctgtaacccgttatttgaa
tcaaaaaatggcgttgagaatgacgaagatcaggaggagtacactctgatgagcattgac
acgatcatcaacggcaaggagggagtgttccagggacttgtaccgattctgaactgctac
ctggagaatatggaggttgacgtagacacacgatgcaccatcttgaactacctgaaactc
attaagaagcgagcatcgggagaactgatgaccatggcgaagtggatgagggaattcgtt
gccaagcatccacagtacaagaaagacagcgtgataactgacaaaataaactacgacctg
ctccgtaagtgcgaccgaattgccaagggagaagagcagtgccctgaactgatcggtgag
ccggtgaaaagaggaaactga
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