Silurus meridionalis (southern catfish): 124400915 Help Entry 124400915         CDS       T08004                                  Symbol mdn1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism smeo  Silurus meridionalis (southern catfish) Pathway smeo03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:smeo00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     124400915 (mdn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:smeo03009]     124400915 (mdn1) Ribosome biogenesis [BR:smeo03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     124400915 (mdn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA_3 AAA AAA_7 AAA_16 AAA_22 TsaE nSTAND3 Sigma54_activat AAA_14 ABC_tran AAA_2 AAA_18 Sigma54_activ_2 AAA_6 Mg_chelatase bpMoxR AAA_29 DUF815 NACHT Dynein_heavy MDN1_4th AAA_28 AAA_8 PduV-EutP AAA_25 VWA_2 TniB VWA dNK Motif Other DBs NCBI-GeneID:  124400915 NCBI-ProteinID:  XP_046728678 LinkDB All DBs Position 18:22251556..22296438 Genome browser AA seq 5520 aa AA seqDB search MESVELSVASLTAVSRHVEKSHGELAKHLAKQTWSQQDRHAVLSCLAQLLLEKDYTLLVA RYLRPLVLDLLERNAERIKKDVRLNHDLHERLCVALSKLLSVSPDAQAFAARYFTSAPPV FQRLFFTSEEASSIQYGPRRMKLRDLMAATLRFLQSDCEKFRVLWDWSVCVSQLLTSDVM VRGYTAQCLALVSHMTDNQKTIFLRKVLSSDEILHLKMKSLEESQQLEVEKALVLANQGS AMWQLEKGNRKGLMGSEDLSKSITAVCGVVLPRLAPRQEEQTSLYTLVLVDSTCRSLRRL AMAVASQKPILLEGPIGCGKTALVEHLAAATGHVKSPDILKVQLGDQTDSKMLLGMYRCT DVPGKFVWQPGSLTQAVSKGYWILLEDIDHAPLDVISVLLPLMENKKLTIPGREDCIQVA PGFQFFATRRTFYSGGAWHRPQSTHAALLDKYWNKLQIGNMTREQLKEVVVKKYPNLTVV VDRLLDIYCQLTGDKHHDAVGLSALQSTTEDRSSLLDGRGLSLRDLLKWCERICVNFDSS SSNTAQNVFLEALDCFTAMLSKTDSRLKLAEIIGSRLNISKEKAQHFCQMYQPGISITEL EVTVGRAMLLRKQSAAVRLNIEKQTFAATRPSAVLLEQLAVCVTKGEPVLLVGETGTGKT STVQYLAGLTGHKLRVINMNQQSDTADLLGGYKPVDHKLILLPLREAFEDLFSQTYSRKQ NITFLGHVQTCFRGKRWQDLLKLMDHVCKSALTKELQDKPNAAMLQQQWEALALRLSQTQ EQIRARESTLVFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSGLLEGSAGSLVLLD RGDTEPLVRHSDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEELESESDLRILVSDYL RGLNLNRSTIHGIISFYLAVRKEANSRLVDGTGHKPHYSLRTLCRALKYVATNPCYNIQR SLYEGFCLSFLTQLDRISHPVVEKLVQQYILGGNIKCLKQPIPEPRSRGCIQIEGYWLSQ GDMDPARDPSYILTPSVRLNLRDLARVVAAGIHPVLLQGETSVGKTSLVRWLAAATGNQC VRINNHEHTDIQEYIGCYSSDEHGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALN RLLDDNRELFIAETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPS EELETILHQRCSLPPSYCTKLVKVMQNLQSLRRGSSVFAGKHGYITLRDLFRWAERYRLE EQTDSSRDWLQHLADDGYMLLAGRVRKPEEASTIQNILEKHFKRTIRPDALFSEAQVTTQ FNPFVASIAGMPEEFGHVVWTASMRRLGVLVGRALRFGESVLLIGDTGCGKTTICQLFAA LTGQKFFAVNCHLHMETSDFLGGLRPVRHTGTGRSEDGRLFEWRDGPLVLAMKQEGMFLM DEISLADDSVLERLNSVLETEKSLVLAEKGSGDDDDVELIIGGKKFRLAATMNPGGDFGK KELSPALRNRFTEIWCPQSNSREDMMKIIQHNLRAGLSLDQHDHQGKDIAELMLDFIDWL TNQEFGRRCILSVRDILSWVDFLNSVCEKDEERHDSSFMGLEEIEEPEWDQRLDTVTALI HTACLVYIDGIGSGTTISAAENVTSARKACLAFLETRLRRITKLDEKMQEALRVYDNTLN REPRWGDDFFGIEPFYIMADHESETRSLLDYTLGAGTTAVNTMRILRALKLQRPILLEGS PGVGKTSLVAALAKASGNQLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGPLLAAL KAGHWIVLDELNLASQSVLEGLNACFDHRAEIYIPELCMRFQVQHEKTKIFGCQNPFTQG GGRKGLPRSFLNRFTQVYVDQLTSEDMQFIGNSIFPNINEQIISKMVRFSNKLVTEVTLE RKWGQKGGPWEFNLRDLFRWCQLMQADQSTAFYNPGQHVGLVYADRMRTEADKAQVLSAF RKVFAEDFEPHVGSRQFHITPLNLQVGSSVLQRSGGAPVVLDPPLSITHQALRPLESLMK CVKMGWMAILVGPSVSGKSSLVHLLALLTGHRLRVMAMNSAMDTTELLGGFEQVDIIRPW QQVLESMDYVVAMVTRRGLMSLDGAVQDTEFLLSTWSTFRRWLRDEGLDTADGTLTFEAL NKLEVIIVLLHKLNTKLKVFTDMSKLQMDFTLLKERLAQMEDGWSRGGFEWLDGTLVQAL QAGDWLLMDNVNFCSASVLDRLNALLEPGGSLTINERGVIDGTTPSITPHPNFRLFLTMD PAHGEISRAMRNRGVEIYIPGENEGACWDSLDLKTILHTLGVTGDCVCDLLMAVHSEIKS TIWDSPASSMSSLLHAAALLSGQLQRGVDLPSALLQACGEAYALCQRTTANQKLAQELIE RQLAVLDSEEWGSGLLCAGVWPDRVPSALQSTEDSCFSTVQRDGQVLLYCLNMLSLQGKR SRPLILTDLQRAMQSGAALETLQFSPESGAGDRIRVAQQLLPTAVRILTERASHSDWVLR TSWLSHLAKSYKHVPDAVLMQLEAGNQALKAAFNSKLVGKGKYLTEQLQPHSTDDYRILV DMRWNKQYLDILANTCNFEDEERCMEFMEALYAVANRIIILLDREERAALCSSTGNASPN HSALRLATAFSKGTVDIAQLPHPVLVHLRSFFDLWDSFVLQAVQTDQPNVSDHLMFEILQ LLQWRDRFWNVCNSLSADARGVCVLSLHWQWVHKHLVLRLPQLLMGDGDYEGQQELQTIS SAIQNTLSSSVSVALALKSIQKTLGKPLPFKLEGVAECSSRLRSFSKVFDVKDLRLNDRK HSLWKREVARLRGVAMRTDCKEALLEGWGLVLQANLLIDAQNTGVLERLHTCVDQQQGHL AACGLLDSLSEAENEEEMEDGAGPDRELLLRLARRAQLWPVLEELAILNQMKVTTDLLHQ SIKHRGTKDHEDEDLRRSLSNHLRFCLQSTPMNVRLLQPLWFLLSTKQPVEELSLVWSEL LSETLAALWCGSVTLDPDRWLKWSPLSPEEESKKSVRSLLGPSDTGPGMLSRAVWSRCVL GVLSSSEAVKWDPSGSSFLTSSRVTLGEWRERIGQLQDLSAVLWDNLAMSELADFRLTDR KLQGLVLCRQLHALSDLLSPGLQESYAESCDVLVEGEDPVGAAQDIQTALREGLPENLLP EGFLETLVTCLTQFSHNRACDMVQLARSGVFWVNMGLLQIQVWVPQTIFDPAVKRAYKLK YAQDELALLQDEWNGRSLSSQLLTGVPLEENSTTDVFQHPRIRYLWIRMQQVKEQICELE RKQACRPEEPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQGSGPKSRPGIQGLLKE EAVWQASQQRFAQRLVDEYPLYPDVVVPLRSAILQLQHGMRLLASQVASTLTVLPGLTDL VSTLLAFPAPPLTSDLERAQYLCSRTCMDTLRGLQKVLPDSEVTHVVPEPVVLLLSALLC LQSHALSAGELGTEAQNLLRHVSQALVNEWDEQERRAREKEQKEASLYRSRSKLHGGGLS EEQQEERDFRRSFPTYHKDFADITAEPSLEQPIIVEDDDDDERDGETSENSIFRVSGCQN SVVQVHQKLCLAFARSLWYQSNPPSDRSKEHLNTLVSSFQITAPLITRFYHLMDCEMDPQ LTGSQLLLSSVLQNTVRGSGGPAGLVLQSEGPYDFYREPNMCEARLCLPVIEQLARAVRR RLEDWPDHPALLQITVVIERILAFSLSSPLAKFLNGLEILLSKSQDWENNASRSVSLRSE LEPVTQLIIQWRKLELNCWSSSLDNALRRHSENSNKHWFSIYQLIERYLQEKRTDDKPDV RESPLVSVSSTLQGFLEGSTLGEFHTRLAMLLAFHCHVLLAPKQEGQASLCSLLWNLHKY YAQFLESIQGRITQLRAPIEKELKDFVKISKWNDVSFWAIKQSVEKTHRTLFKFVRKFEA ALAGPCAPWLLEKPTSASAKAMDVHQEDAPLHQLHRALQSALPGRSRDLQNDGPEELRSD EPPSLQARLPTLTRKMRKMCVRLVKSSPLPELSEDLDQFTGEIVSNVQALQSLTVNRTLE QERQKSEAKHILLQKQRALADLFKMLAQIGLSYRKGLTWARTSDQEEPLFLQPVEMRTTL ATLGAQEPTETILFAEMNSTWDGCQKYFYRSWARRNAMQAAMQAAVKELGLGNIERCRGF SSHLFKLLLKQRRRLAKITTHFVDLRRLIDTIQDVRSQEDTEEAVLPPQDSLSSWVAKAR ALAQRCSVALQQLSWVLQCCPEGSNGTACQSREGDGGQGEATLSHPTPLSPHLQPQVCLM RRGEASWTEAEKIIAALQSESTELKDRLNALGCESTQRAIQTRRHLKECCSCVQGLGALA GRMAALERLFELDGSDAPRSQPCLTRGLRGVRAEVDTCVVEFTAWNSQLPPIRTSSKRSA ASFRAEFSEELERTINAVLCGVQGLVKRKEQERQEGQPEDSKKESDSEAAEELLKPGHLS RLMEEDLSGDVTCLALAEVIGLLERLLEKLRSFRDTCKARHLGELSEACRGLVRLEPMLC VYCELVRWYVAVCMGAHRSTAKLLSVLASIFTDLAQKGFCLPQELTGGGDGEGATEFHDY EGGGIGEGEGVKDVSDKIENEDQVEDTLREGEEKSEEEPDKRDIGEEDDAIEMSEDFDGK MHDGETRDSDDEQDSDKDEDEELDKKMGDLGDGATDTLDERMWGDDEDDEDDAENSDKED ESGPGMDQGESELVAKDDNAEAGESNKEQKNEDKDKPMEHEGEKEKIHEQEDEREFDENE VDPYHGKQEQKAEIEAMDLPEELNLDQDEQGGQDEEEAGDGDADNPYDIEDKPMEVDEAE GDGDGEDEKAEEMTEEQQDDRGDEANEEEPGEEQKGRDEDLERGESEGEQDEDEKEKGHE GRGDEDKENKAGPGDEGEKPKEEEDEEDEDVHKEAAERKEHSTDGQTGEENVQSETAVEL AGAASERDQAKEEHGSGAADASQAEGHDSTLMARMSSQRQRQKQTQGFKRKPGRADTERS LGDASERVHKRLRTIDSADRSEQDRSRDDTQQESDLYEHVRHGEETCDTQTYDTANAEQQ RPAPTKQEDDDENDADVAMDAEEDKEMQAVEAPELKPEKLESTKASHKGMESAEQDSQQH EKDNEEKPEAKSRKEDPRTERSRESTIHTVPELLTEMLKLQVKDPDLLRKDLELQLEAWH KQTPGSPEEEIAAAAMWQQYHALTSPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMR KVIPYIASQFRKDKIWLRRTKPSKRDYQICLAVDDSSSMVDNHSKQLAFESVSVIVNALT LLEVGQVAVCSFGESVQLLHPFQQQFNDQSGARILRLCQFQQKKTRIAQFLETSADMFVA AKQQNPGSGNTEMAQLLLVVSDGRGLFLEGKERVAAAVQAARSNNIFVIFVVLDNPNSRD SILDIKVPIFKGPGELPEIRSYMDEFPFPFYMILRDVNALPETLSDALRQWFELVTATDR NT seq 16563 nt NT seq  +upstreamnt  +downstreamnt atggaaagcgtggagctgagcgtcgcgtccctcaccgcggtgtccagacacgtcgagaaa agtcacggcgagctcgcaaagcacctggccaagcagacatggagccagcaagaccgtcac gccgtgctgtcctgtttggcgcagctcctcctcgagaaggattacacgctcctggtcgct cgctaccttcgtcccctggtgctcgacctgctggagaggaacgccgagcggatcaagaag gatgtccggctgaaccatgacctccacgagaggctgtgcgtggcgctcagcaagctgctc agcgtcagccccgacgcacaggcgttcgcggccaggtacttcactagtgcaccgcccgtc ttccagaggctcttcttcacgagcgaagaggcctcctcgatccagtacggccccagacgc atgaagctgcgcgacctcatggcggccacgttgcgcttcctccagagcgactgcgagaag ttccgcgtgctgtgggactggagcgtgtgcgtctcgcaactgctcaccagcgacgtcatg gtccgaggatacacagcgcagtgcctcgccctggtgtcccacatgaccgacaaccagaaa accatcttcctgaggaaggttctgtccagcgatgaaatcctgcacctcaaaatgaagtcg ctggaggagtctcagcagctagaggtggagaaagcgctggtgttggccaatcagggctca gcgatgtggcagctggagaaaggaaacagaaagggtctgatgggctccgaagacctctcg aagagcatcacggcggtgtgcggcgtggtcctgcccagactcgcgcccagacaggaagag cagacgtctttgtacaccctggtgctggtggactcgacgtgtcgcagcctaaggaggctc gccatggccgtagcgtcccagaagcccatcctcctggaagggccgatcggatgcggcaaa acggcactcgtcgaacacctggccgctgctactggtcacgtgaaatcccccgacatcctc aaggtgcagctgggagaccagacggacagcaagatgttgctcgggatgtaccggtgcaca gacgtcccagggaagttcgtctggcagccggggtccctcactcaagccgtctccaagggt tactggatcctcctggaggacatcgatcatgcgccgttggatgtgatatccgtgctgctg ccactgatggagaacaagaagctgaccattccgggccgtgaagactgcattcaggttgct cctggcttccagtttttcgctacaagacggacgttctacagcggaggagcctggcatcgt cctcagagcactcacgctgctctactagacaagtactggaacaagctccagattgggaat atgaccagagagcagctcaaagaggtggttgtgaagaagtacccgaacttgaccgtagtg gtggatcgtttactggacatttattgtcagttgaccggagacaaacaccatgacgcggtc ggtctttcagctcttcagagcacaacagaggaccggagctcgctcctggacggccgagga ctctctctgagggatctgctgaagtggtgcgagagaatctgtgtgaattttgacagctcc tcctctaacacggcccagaacgtcttcctggaggccctggactgcttcaccgccatgctg tccaaaacagacagccgcctaaagctggccgagatcattggctccaggctcaacatctct aaagagaaggctcagcacttctgtcagatgtaccagccgggaatcagcatcacagagctg gaggtgaccgtaggacgcgccatgctgctgcggaaacagagcgccgccgtgcgccttaac atagagaagcaaacgttcgctgccacccggccctccgccgtgcttctggagcagctggcg gtgtgcgttacgaagggagagcccgtgttgctggttggagagacgggcacagggaagacc tccaccgtgcaatacctagccggattaacaggacacaagttgcgtgtgatcaacatgaac cagcagagcgacacggctgatctcctgggagggtacaagccagtggaccacaagctcatc ctgttgcccctccgtgaggcatttgaggaccttttctctcagacgtactcacgcaagcag aacatcaccttcctgggtcacgtgcagacgtgtttccggggcaaacgctggcaggacctg ctcaagctcatggaccacgtgtgcaagtcggctctcaccaaggagctgcaggacaagccg aatgccgcgatgctgcagcagcagtgggaggccctcgctctgaggctcagtcagacccag gagcagatccgagctcgggaatcgacgctggtctttgcctttgtcgagggtaccttggcg caagcagtcaagaagggagagtggattctgctcgatgagatcaacctggcggctgcagag accctggagtgtctcagcgggcttctggaaggcagtgccgggtctctggtgctgctggat cggggcgatacggaacccctggtccgccactcagacttccgcctgttcgcctgcatgaac ccggccaccgacgtgggcaaaaggaacctccccctgggaatccgcaaccggtttaccgag ctctacgtggaagagctggagagcgagagcgacttgcgcatcctggtctcagattacctc cgaggcttaaacctgaaccggagtaccatccacggaatcatcagcttctatttagctgtt cgcaaggaggccaactcacgtttggtggacggtaccggccacaaacctcactacagcttg cggacgctgtgccgtgcgctcaagtacgtcgccacgaacccctgctacaacatccagcgc tcgctctatgagggtttttgcttgagttttctaacgcaactggaccgcatttcccatcct gtggtggagaaactggtgcagcagtacattttgggaggaaacatcaagtgtctcaaacag ccgatcccagaaccccggtcccgtggctgcatccagatagagggctactggttgagtcaa ggcgatatggacccagcacgagaccccagctacatcctcactccatctgtccgactcaac ctccgagatctggcccgagtggtggctgctggcatccacccggtgttgctccagggtgag acgtcggtagggaagaccagcctggtgcggtggctcgcggccgccacggggaaccagtgc gtacggatcaacaaccacgagcacaccgacatccaggagtacatcggctgctactcttcc gacgaacacgggaagctcgtcttcaaagaaggtgtcttgatcgacgcaatgcgcaaaggc tactggatcatcctggacgagctgaacctcgcccccaccgacgtcctcgaagccctaaac cggctgctagacgacaaccgggaactctttatcgccgagacccaggaagtggtgaaagcc catcccaggttcatgctcttcgctacccagaacccaccaggtctctacggtggcagaaag gtcctgtcaagggcgttcaggaatcgctttgtggagctgcactttgacgagttgcccagc gaggagctggaaaccatcctgcaccagcgctgcagccttcctccatcgtattgcactaaa ctggtcaaagtcatgcagaaccttcagtcgttgcggcggggctccagcgtgttcgccggg aagcacggctacatcacgctcagagatctcttccgatgggccgagcgctacagacttgaa gaacagaccgactcgtcacgtgactggctccaacatctcgcagacgacgggtacatgctc ttggcgggccgtgttcgtaagccagaggaggcttcgaccatccagaacattttggagaag cactttaagaggacgataagaccggatgcattgttttccgaagcccaggttaccactcag ttcaatccatttgtggccagcattgcaggaatgcctgaggagttcggtcatgtggtttgg accgcaagcatgaggaggcttggtgttctggtgggccgtgcgctccgtttcggagagtca gtcctcctgattggtgataccgggtgtgggaagaccacaatttgccagctctttgccgct ctgactggacagaagtttttcgctgtgaattgccacttgcacatggagacgtcggatttc ttgggcggcttgcggccggtccgacacaccggaacaggacggtcggaagacgggcgcttg tttgaatggcgcgatggacccctggtgcttgcgatgaagcaagaaggcatgtttttgatg gacgagatctcgctggctgatgactccgtgttggaaagactcaacagcgtcctggagact gagaaatctctggtcctggcggagaaaggcagtggcgacgatgatgacgtcgagctcatc ataggtgggaagaaattccgactggctgccactatgaaccccggtggcgattttggcaag aaagagctttccccggcgttaaggaaccggttcacagagatctggtgtcctcagtcgaac agccgtgaagacatgatgaagatcatccagcacaacttgcgagcagggctatctttagac cagcacgaccatcaaggcaaggacatcgccgaactcatgctggactttattgactggctg accaatcaggagtttgggaggcgctgcatcctaagtgtaagggacatcctgtcgtgggtg gacttcctgaactccgtgtgcgagaaggatgaggagaggcatgatagcagcttcatgggt ctggaggagatcgaggagccggagtgggaccagaggcttgatacggtcacggccctcatc cacaccgcctgccttgtatacatcgacggcatcggatcagggacgaccatctccgcagcc gagaatgtgacgtcggcaagaaaggcctgtcttgcttttctggagacaaggctacgccgg atcaccaagctcgatgagaagatgcaggaggccctgagggtttatgacaacactctgaac cgagagccacgctggggggacgacttctttggcatcgagccattctacattatggccgat catgagagcgaaacccgcagtctgttggactacactctgggggccggcacgacggcggtg aataccatgcgcatcctacgggctctgaagctccagagacctatcctgctggagggttcc cccggagtgggcaagactagtctggtggccgcacttgccaaggcctctggcaaccaactc gtcagaatcaacctctcggagcagacagatgttaccgacctgtttggaactgaccttcca gttgagggcggtaaagggggggagtttgcttggcgtgatggtcctctcctggctgctctg aaggctggacattggattgtcctagatgagctgaacttggcctcccagtcagtgttggag ggtctgaacgcctgctttgaccaccgagcagaaatctacatcccggaactgtgcatgcgt ttccaggtccagcatgagaaaaccaagatctttggttgccagaaccctttcacgcaggga ggaggtcgcaaaggtttacccaggtctttcctcaacaggtttactcaggtgtacgtggac cagctcaccagtgaagatatgcagttcattggcaactctatctttccgaacatcaatgag cagattatctctaaaatggtccggttcagcaacaagcttgtgaccgaggttacattggag agaaaatggggtcagaaaggaggaccgtgggagtttaacctgcgagacctcttccgctgg tgtcagctgatgcaagccgaccaatccacagcattctataatccgggtcagcacgtcggc ctggtttatgccgaccgcatgagaacggaagcggataaggctcaggtgctgtctgcgttc aggaaggtgttcgccgaagatttcgagcctcacgtgggctccaggcagtttcacattacg ccactgaatctgcaggttggctcgtcagttctccagcgcagcgggggagcgccagtcgtc ttggatcctcctctttcgatcactcatcaagccctgcggccactggagtccttgatgaaa tgcgtaaaaatgggatggatggccatactggtgggccccagcgtcagcgggaaaagcagt ctggtacacctgctagccttgctgaccggacacaggctgagggtgatggccatgaatagt gccatggacactaccgaactgctgggtggattcgagcaggtggacatcatcaggccctgg cagcaggtcttggagagtatggactacgtggtggctatggtcacacgacgtgggttgatg tctctggacggggcggttcaggacacagagtttcttctgagcacctggagcacgttccgt cgctggctgagggacgaggggcttgacacggccgatggcactttgacgttcgaggccttg aacaagctggaggtcatcattgtgctgctccacaagctcaacaccaagctcaaggtcttc acagacatgtcgaagcttcagatggacttcaccctcctgaaggaacgtttggcgcaaatg gaggacggttggagtcgcggcgggttcgagtggctggacggcacgttggtccaagctctg caggccggggactggcttctcatggacaacgtcaacttctgcagcgcgtctgtcctggac cgactaaatgctctcctggaaccgggcgggtctctaaccattaatgagcgtggggtcata gacggcacgacgccaagcatcactccacaccctaacttcaggctgttcctcaccatggac cctgcgcacggagagatctcccgtgctatgaggaaccgcggcgtcgagatctacatcccg ggagagaacgaaggtgcttgttgggactcgctggacctgaagaccatcttacacactctg ggagtgacgggagattgcgtgtgcgacctgctgatggccgttcattccgagatcaagtcg accatctgggattcaccagcgtcctcaatgtcatctctgctgcatgcggccgcattgctg tctggtcagctacagagaggggtggatctgcccagcgccctactgcaggcatgtggtgaa gcgtatgccctctgtcaacgcaccactgccaaccaaaagctggctcaggagctgatcgag aggcagcttgctgtgttggattccgaagaatggggcagtggactgttgtgcgcaggcgtg tggccggatcgagtaccctctgctctgcagtctacagaggactcgtgtttttccactgtc cagagggacggccaggttctcctctactgtttgaacatgctcagcctgcagggcaagagg agtcggccgctgattctgaccgacctgcagagggcaatgcagagcggcgcggccctggag acgctgcagttctctccagaaagcggggcaggtgaccggataagggtcgctcagcagctc cttcccacggcagtgcggatcctgaccgagagggcctcccacagcgactgggtcctgcgt accagctggctctcacaccttgccaaaagctacaaacatgtaccagatgcagtgctgatg cagctggaggcgggaaatcaggctctcaaagcagcctttaacagcaagcttgtgggcaag ggcaagtacctgaccgaacaacttcaaccccacagcacagatgactacaggatcctggtc gacatgcgctggaacaaacagtacctggacatcttggccaacacatgtaactttgaggat gaggagcgctgtatggagttcatggaggcgctctatgctgtcgcaaacaggatcattatt ctcttggaccgggaggagagagcagctttatgcagcagcactggaaatgcgtcacccaat cacagtgcactaagactggccaccgccttttccaaaggaacagtagacattgcacagctg ccgcatccggtccttgtgcatctgcgctctttctttgacctgtgggactctttcgtgctg caggccgtgcagacggatcagccgaacgtttcggaccacctcatgttcgagatcttgcag ctcctccagtggagagaccgtttctggaacgtgtgtaactccttgtcagcggacgcccgc ggagtctgtgtcctctccctgcactggcagtgggtccacaaacacctggtacttcgtctg ccccagctcctgatgggcgatggcgactacgaagggcagcaagagctgcagacgatctcc tcggcgatccagaacacactttccagctctgtgtctgtagccctggcactaaagagcatt cagaagaccctgggaaagccccttccttttaagttggagggtgtggccgaatgctcctcc cgtctccgctcgttcagcaaagtgttcgacgtcaaggatttgcgcctgaatgacagaaag cactcgctgtggaaacgggaagtggcccgtctgcggggggtcgccatgagaacagactgc aaggaagccttgctggaaggctggggtctggtccttcaggctaacctcctaatcgatgca cagaatacaggagtcctggagaggttacatacctgtgtggatcagcagcagggacacttg gctgcctgtggcctcctggattctctgtccgaagcagaaaacgaggaagagatggaagac ggtgcgggtccggaccgcgagctgttgctgcggctggctcgccgggctcagctctggccc gtcctggaggaactcgccatcctcaaccagatgaaagtgaccaccgatctgctgcaccag tcgatcaaacacagaggcaccaaagatcatgaagatgaagatctccgacgatccctgtcc aaccacttgcgcttctgcttgcagtccacgcccatgaacgtccgtctgcttcagccactc tggttcctcctcagcacgaagcagcctgtagaagaactatcgttagtttggtctgagctg ctttcggagacgctggcagcgctctggtgtggcagtgtgaccttagatcctgatcgctgg ctgaaatggagtccactgagtccagaagaggagtccaagaagagcgttcgatcactgctg gggccctctgatacgggtccaggcatgctgagccgagctgtgtggtcccggtgcgtgctg ggagttttaagcagcagtgaagcagtgaagtgggacccgtcaggctcctccttcctgacc tcatcacgggtgacgctgggcgagtggcgagagaggattgggcaactccaggacctcagt gctgtgctgtgggacaacctggccatgtccgaactggctgattttagattgacagaccgc aagttgcagggcctggtgttatgccggcagctgcacgctctctcggaccttctgtctcca gggttacaggagagctacgcggaatcctgtgatgttctcgtggaaggcgaggacccagtc ggggcagcgcaagatattcagactgccttgcgagaaggcctccctgaaaacttgctccca gaaggcttcctggaaaccctggtgacttgcttgacccagttctcccataaccgggcttgt gacatggtccagctggcccgctctggggttttctgggtgaacatgggtctgctgcagatc caagtctgggtcccccagacaatattcgacccggcggtcaagagggcttacaaactcaaa tacgcacaagatgagctcgccttacttcaggatgaatggaatgggcgaagtctatcatcg cagctgctcacaggggtgccgcttgaagaaaacagcaccaccgacgtctttcaacatccc agaatcaggtacctgtggatccgaatgcaacaggttaaagaacagatctgcgagctggag agaaaacaggcgtgtcggcccgaggaaccccagtatggacgcctgtaccaggagctccag cactacctgtgcagcattggccagccagcggccgtaggcgacctcctgtcgcacctcctc aaggccctgcagggctccgggcccaaatctcgcccaggaatccagggcttgttaaaggag gaggctgtgtggcaggcatcgcagcagcgttttgcgcagcgcctggttgacgagtacccg ctgtacccggatgtcgtggtccccctacgctcagctatcctgcagctgcaacatggcatg cgtctgcttgcttctcaagtggcgtctactctcactgtgcttccgggtctcactgacctg gtctccacgcttctggcttttcctgcaccacccctgacctccgacctcgagcgtgcacaa tacctgtgctctcggacgtgcatggataccctccgtggactgcagaaggtgcttcctgac tccgaagtgacccacgtggtcccagagcctgtcgtgttactgctcagcgctctgttgtgt ctgcagagccacgcgctaagtgcaggagagcttggcacggaagcacaaaatctgctcaga catgtttctcaggcgttggtgaacgagtgggatgagcaagagaggagagcaagagagaaa gagcagaaggaggccagtttgtatcgcagccgctctaaactacacggtggaggactcagc gaggagcagcaggaggagcgcgatttcagacgctccttcccgacataccacaaagatttt gcagacatcaccgccgaacccagtctggagcagccaatcattgtcgaggatgacgatgac gacgaacgcgatggagaaacttccgaaaacagcatcttccgagtctctggctgccagaac tctgtcgtgcaggtgcatcagaaactgtgcctggccttcgcacgatcactgtggtaccag tcaaatccaccgagcgaccggagcaaggaacacctcaacactttggtctcgtcttttcag atcaccgcaccattaataactcgattttatcatcttatggactgtgaaatggatcctcag ctgacaggctcccagctgctactcagctccgtactgcagaacaccgtccggggttctgga ggtccggctggcctcgttctccagagcgaaggtccttacgacttctatcgggagccgaac atgtgcgaagcccgcctgtgccttcccgtcatcgagcagttagcccgtgcagtccgtcgc cgcctagaagactggcctgatcacccggcgctcctgcagatcactgtggtgatcgagagg atcctggcattcagtctgtccagcccgctagccaagttcctaaatgggttggagatcttg ctcagcaaatcccaggactgggaaaataacgctagtcgatccgtgtctctgaggagcgag ttggagcctgttacacagctcatcatccagtggaggaaactggagctcaactgttggtct agcagtctggataacgctctgaggcggcactcggagaactccaacaagcactggttctcc atctaccagctgatcgagagataccttcaggagaaaaggacagacgacaaacccgatgtg agggagtctcccctggtttcagtttcatccacgctgcagggattcctggagggatccacg ctgggcgaatttcacacacgcttggccatgctgcttgccttccactgccacgtgttgttg gcgccgaaacaagaaggacaagcctcgctgtgtagtttgctgtggaacctgcacaagtac tacgcacagttcttggagagcatccagggcaggatcacgcagctcagagcgccaatcgaa aaagaactcaaggactttgtaaagatctccaagtggaatgacgtcagtttttgggctatc aagcagtcggtggagaaaacgcacaggactctgtttaagttcgtgagaaagttcgaggct gccttggccgggccgtgtgccccctggctgctggagaagcccaccagcgctagcgcgaaa gccatggacgtccatcaagaggacgcgccactgcaccagcttcaccgcgcgctccagagc gccctccctggacggagccgagacctacagaacgacggtccagaggagttgaggtctgac gagccgccatccctgcaagctcgcttacctacgctcacgaggaagatgaggaagatgtgc gtgcggctggtgaagtcgtcacctctgcctgagctgtctgaggacctcgaccagttcaca ggagagatcgttagcaacgttcaggctctgcagagtttaacggtgaaccgcacactggag caggagaggcagaaatccgaagcgaagcacatcctgctgcagaaacagcgcgctttggcc gacctctttaagatgctggcgcagatcggtctgtcgtatcgtaaaggcctgacgtgggct cggacctccgaccaggaggagccgctctttttgcagcctgtagagatgagaactactttg gccacactgggagcacaggaaccaacagaaaccatactgtttgctgagatgaacagcaca tgggatggatgtcagaaatatttctatcgctcctgggccagacgtaacgccatgcaagct gccatgcaggcggccgtaaaggaactcgggttaggaaacatagagcgatgccggggcttc tcctctcacctgtttaagctgctgcttaaacaaaggcgccgactcgccaaaataacaacg cacttcgtggacctcagaaggttgatcgacaccatccaggatgtccggtctcaggaagac accgaggaggccgttcttccgcctcaggattctctcagcagctgggtagcgaaggcccga gcgctggcgcagcggtgctccgtggccctgcagcagctctcatgggtgctccagtgctgc cccgaggggtccaacggaacggcgtgccagtccagagagggcgatgggggccagggagag gccacactgagccacccaacgcctctgtcgcctcaccttcagcctcaggtatgtctaatg aggcggggcgaggcgagttggaccgaggcggagaagatcatcgcggctttgcagagcgaa agcacggagctgaaggacaggctcaacgcgctgggatgtgaatctacacaaagagcgatc caaaccaggaggcacttgaaggagtgctgctcatgcgttcagggtttgggggcgctcgca ggacggatggcggctctggagcgcctctttgagctcgatggcagcgacgcgcctcgttcg cagccgtgtctgacccgaggtctgcgcggcgtcagggcggaggtggacacctgcgtcgtg gagtttactgcctggaattcgcaactgccgccaatcaggacttcatccaaacgttcagcc gcgtcgttccgggccgagttctccgaggaactggagagaaccataaatgcggttctgtgt ggagtacaagggctggtgaagagaaaagaacaggaaaggcaggaaggtcagccagaagat agcaagaaagagagcgactctgaagcagccgaggagcttctgaaacccgggcacctaagc cgcctaatggaggaggacctgagtggagacgtgacgtgtcttgccttggctgaggtcata gggcttttggagaggttgctggagaagctgcggtccttcagagacacgtgtaaggcacgt catttaggggagctgagcgaggcctgcaggggtcttgttcgtctggagcccatgctgtgt gtgtactgtgagctggtgcgctggtacgtggcggtgtgtatgggcgctcaccgcagcacg gccaaactgctgtctgtcctcgccagcatctttactgacctcgctcagaagggcttttgt ttgccccaggagctcacaggcgggggcgatggcgagggagccacggagttccacgactac gagggcggagggatcggagaaggagagggtgtcaaggacgtgagcgacaagatcgaaaat gaggatcaggtcgaagacacgcttcgcgaaggagaggaaaagagcgaagaggagccggac aagcgcgatatcggagaggaggacgatgccatcgagatgtccgaggacttcgacgggaaa atgcacgacggcgagacgcgagactctgatgatgaacaggattccgataaagatgaggac gaagagctggataagaagatgggagacctgggagacggcgcgactgacacacttgatgag cgcatgtggggtgatgatgaagatgacgaggatgatgcggagaacagtgacaaagaggac gaatccggcccgggaatggaccagggtgagtccgagttggttgccaaagacgacaatgca gaagccggcgagtcgaataaagagcagaaaaacgaggacaaggacaaaccaatggagcat gaaggcgagaaggagaaaatccacgagcaggaagatgagcgtgagttcgatgagaatgag gtggacccctaccacggtaagcaggagcagaaagccgaaatagaagccatggaccttccg gaggaactcaatctggaccaggatgaacagggaggacaggacgaagaggaagctggagat ggagatgccgacaacccgtacgacatcgaggacaaacccatggaggtggacgaggcagag ggagacggggatggagaagacgagaaagctgaagagatgacagaagagcagcaggatgat cgaggcgacgaagcaaacgaggaagagccgggagaggagcaaaaaggccgagacgaagat ttggagagaggagaaagcgaaggagagcaggacgaggacgagaaggaaaaggggcacgaa ggacgtggagatgaggacaaggagaacaaggccggacctggagatgagggcgagaaacca aaggaagaggaggacgaggaggatgaggacgtccacaaggaagctgccgagaggaaggag cactcgacagatggccagactggcgaggagaacgttcagagcgagacagcagtggagcta gcaggagccgcgtccgaaagagaccaagccaaagaggaacacgggagcggagcggctgat gccagtcaggctgagggacacgactccacgctgatggccaggatgagctctcagaggcag agacagaaacagacacagggtttcaagcggaaaccgggccgggcggataccgagcgctct ctaggggacgccagcgagcgcgtgcacaagcgtttgcggacgatagacagcgcagatcgg agcgagcaggaccgctcccgcgacgacacccagcaagaatccgatctgtacgaacacgtc agacacggggaggagacgtgcgacacgcagacctacgacacagccaacgccgagcaacag agaccggcacctacgaagcaagaagacgacgatgaaaacgatgctgacgttgctatggat gccgaggaggacaaggagatgcaggcggtggaagctccagagctcaagccggaaaagctg gagagcaccaaagcctctcataaaggtatggaaagcgccgaacaggactcccagcagcat gaaaaggacaatgaggagaaaccagaggcgaagagtcgcaaggaagatccgagaacggag aggagtcgagagtccaccatccacaccgtgccagagttactaacagaaatgctgaagctc caggttaaagatccagacctgctcaggaaagatttagagctgcagttggaagcgtggcac aagcagaccccaggatctcccgaagaggagattgccgcagcggccatgtggcagcagtac catgcgctcacctcacctctgtcgcagcagctgtgcgaacaacttcgtctcatcctggag cccacgcaagccgctaagctcaaaggtgattatcgcacgggaaaacgtctgaacatgcgc aaagtcattccctacatcgccagccaattccgcaaagacaagatctggctgaggaggaca aagcccagcaagagagattatcagatctgcttggctgtggacgactcgtccagcatggtg gacaaccactccaaacagttggcgttcgagtcggtctcggtgatcgtgaacgctctcacc ctgctggaggtggggcaggtggcagtctgcagcttcggcgagagcgtccagctgctccac ccgttccagcagcagttcaacgaccaatcaggagcccggatcctgcggctgtgccagttc cagcaaaagaagacgagaatagctcaatttctggagacttcagccgacatgtttgtggcg gccaaacagcagaatccaggctctgggaatacagaaatggcacagttgctgctggtggtc tcagacggcaggggtttgttcctggaggggaaggagagagtagcagcagcggttcaggcg gctcgcagcaacaacatcttcgtcatattcgtggtgctggacaaccccaactccagggac tccatattggatatcaaagtacccatatttaaaggtccgggcgagcttccggagatccgc tcctacatggacgagttcccgtttccgttttacatgattctgcgggacgtcaacgccctg cctgagacgctgagcgacgctttgaggcagtggttcgagctcgtcaccgccaccgaccgg taa

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