Streptomyces mirabilis: SMIR_07450
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Entry
SMIR_07450 CDS
T10322
Symbol
hemE
Name
(GenBank) uroporphyrinogen decarboxylase
KO
K01599
uroporphyrinogen decarboxylase [EC:
4.1.1.37
]
Organism
smib Streptomyces mirabilis
Pathway
smib00860
Porphyrin metabolism
smib01100
Metabolic pathways
smib01110
Biosynthesis of secondary metabolites
smib01240
Biosynthesis of cofactors
Module
smib_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
smib00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SMIR_07450 (hemE)
Enzymes [BR:
smib01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.37 uroporphyrinogen decarboxylase
SMIR_07450 (hemE)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
URO-D
Methyltransf_11
Motif
Other DBs
NCBI-ProteinID:
QUW78952
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All DBs
Position
complement(1666545..1667615)
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AA seq
356 aa
AA seq
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MSTDDRPATGQPPTATYESAFLKACRREPVPHTPVWFMRQAGRSLPEYLKVREGIAMLDS
CMRPELVAEITLQPVRRHNVDAAIYFSDIVVPLKAIGIDLDIKPGVGPVVANPIRTRADL
AQLRDLTPEDVWYVTEAIKLLTAELGETPLIGFAGAPFTLASYLVEGGPSKNHEHTKALM
YGDPQLWADLLDRLAEITSAFLKVQIEAGASAVQLFDSWVGALAPADYRRSVMPASAKVF
ESVAGYGVPRIHFGVGTGELLGLMGEAGADVVGVDWRVPLDEAARRVGPGKALQGNLDPA
VLFSTTEAVETKTREVLDAAAGLEGHVFNLGHGVPPSTDPDALTRLVAYVHQQTAR
NT seq
1071 nt
NT seq
+upstream
nt +downstream
nt
gtgagtaccgatgaccgccccgccacgggccagccgccgacagccacgtacgagtccgcc
ttcctgaaggcgtgcaggcgcgagcccgtgccgcacacgccggtgtggttcatgcggcag
gccgggcgctcgctgcccgagtacctgaaggtgcgcgagggcatcgccatgctggactcc
tgtatgcggcccgagctggtcgccgagatcacgctccagcccgtacgccggcacaacgtg
gacgcggcgatctacttcagcgacatcgtcgtcccgctgaaggccatcggcatcgacctc
gacatcaagccgggcgtcggcccggtcgtcgcgaacccgatccgcacccgcgccgacctg
gcccagctgcgcgatctgacccccgaggacgtctggtacgtcaccgaggcgatcaagctc
ctgacggccgagctcggcgagaccccgctcatcggtttcgcgggcgcgcctttcaccctc
gcgagttacctcgtggagggcggcccgtccaagaaccacgagcacaccaaggcgctcatg
tacggcgacccgcagctgtgggccgacctgctcgaccgtctcgccgagatcacctccgcc
ttcctgaaggtgcagatcgaggcgggcgcgagcgccgtccagctcttcgactcctgggtc
ggcgccctggcacccgccgactaccggcgctcggtgatgcccgcgtccgccaaggtcttc
gagtccgtggccgggtacggcgtgccgcgcatccacttcggcgtcggcaccggcgaactg
ctcggcctcatgggcgaggcgggcgcggacgtcgtcggcgtcgactggcgcgtcccgctc
gacgaggccgcgcgccgtgtcggcccgggcaaggcgctccagggcaacctcgaccccgcc
gtcctcttctccaccaccgaggcagtcgagaccaagacccgcgaggtgctggacgccgcc
gccggtctcgagggccatgtcttcaacctcgggcacggcgtcccgccgagcaccgacccg
gacgcgctgacccgcctcgtggcgtacgtccaccagcagaccgcgcgctga
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