Streptomyces mirabilis: SMIR_09710
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Entry
SMIR_09710 CDS
T10322
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
smib Streptomyces mirabilis
Pathway
smib00290
Valine, leucine and isoleucine biosynthesis
smib00660
C5-Branched dibasic acid metabolism
smib01100
Metabolic pathways
smib01110
Biosynthesis of secondary metabolites
smib01210
2-Oxocarboxylic acid metabolism
smib01230
Biosynthesis of amino acids
Module
smib_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smib00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SMIR_09710 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMIR_09710 (leuC)
Enzymes [BR:
smib01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SMIR_09710 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SMIR_09710 (leuC)
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Paralog
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Motif
Pfam:
Aconitase
DUF4946
BON_like
Motif
Other DBs
NCBI-ProteinID:
QUW79356
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All DBs
Position
complement(2248311..2249735)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIAKIGTGGGQGYILEYRGSAVEKLSMEARMTICNMSIEAGARAGMIAPDETTF
EYLKGRAHAPEGEEWGAAVAYWKTLKSDEDAVFDAEVVIDGPSLAPFVTWGTNPGQGAPL
SASVPDPASYEDASERMAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAA
IVEGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPVPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgccaggcggggcgtcccgtgcgccgtctcgacctcaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgcggacccagtctcccgg
gcccagctggagaccctgcgcaagaactgcgccgagttcggtgtacggctgcactcgctg
ggtgacgtcgagcagggcgtcgtccacgtggtgggaccgcagctgggtctgacccagccc
ggcaccaccgtggtctgtggcgactcccacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcacctcgcaggtcgagcatgtgctggccacccagacgctgccgctg
gcccgccccaagaccatggccatcacggtcgacggcgagctgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggtacgggtggcggccagggctacatc
ctggaataccgcggctccgccgtcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gagtacctcaagggccgtgcgcacgcccccgagggcgaggagtggggcgccgcggtcgcg
tactggaagaccctgaagtcggacgaggacgcggtcttcgacgccgaggtcgtcatcgac
ggcccgtcgctggcgccgttcgtcacctggggcaccaaccccggccagggagcgccgctt
tcggcgtccgtccccgacccggcttcgtacgaagacgcttcggagcgcatggccgccgaa
aaggccctggagtacatggggttgaccgccggacagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgcg
atcgtcgagggccgcaaagtcgccgacggcgtacggatgctggtggtccccggttccgcg
cgggtcggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctcgaaccgtaacttcgagggcaggcagggcaagggcggc
cgtacgcatctcgtatcgccgcaggtggccgccgcgaccgcggtgctgggccacctggcc
tccccggccgacctgtccgacgcccccgtgcccgctggagtctga
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