Streptomyces mirabilis: SMIR_15910
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Entry
SMIR_15910 CDS
T10322
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
smib Streptomyces mirabilis
Pathway
smib00290
Valine, leucine and isoleucine biosynthesis
smib00770
Pantothenate and CoA biosynthesis
smib01100
Metabolic pathways
smib01110
Biosynthesis of secondary metabolites
smib01210
2-Oxocarboxylic acid metabolism
smib01230
Biosynthesis of amino acids
Module
smib_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
smib_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
smib00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMIR_15910 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SMIR_15910 (ilvD)
Enzymes [BR:
smib01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SMIR_15910 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
QUW80432
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Position
complement(3622396..3624249)
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSEAITAAGGIAREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICI
SNCDKITPGMLMAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKGLYEDAART
VVEITHRYYDQDDESVLPRNIATHAAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
DEINEVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHSVHSP
SLSDWLKTWDVRAGSPSPEAIELWHAAPGCVRSSEAFSQSERWEALDEDAENGCIRSAEH
AYSKDGGLAVLKGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVDKILRKEITHGD
VVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVQDGDRIHIDIPNRSIELLVSDEELATRRSALNGVYAPANRDRKVSAALRAYAA
MATSADKGAVRDVSKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaatatggcgggcgcacgcgcc
cttatgcgcgcctccggtgtaccgggcgcggacatcggacggaagccgatcatcgcggtc
gccaactccttcacggagttcgtgccgggccacacccacctccagcccgtcggccgcatc
gtcagcgaggcgatcaccgcggccgggggcatcgcgcgcgagttcaacacgatcgcggtc
gacgacggcatcgcgatgggccacggcggcatgctgtactccctgccctcccgcgacctg
atcgcggactcggtcgagtacatggtggaagcccactgcgccgacgccctgatctgcatc
tcgaactgcgacaagatcacccccggcatgctcatggcggccctgcgcctgaacatcccg
acggtcttcgtctccggcggccccatggagtccggccgcgccaccctggtcgacggcacg
gtccgtacgctcgacctggtcgacgcgatctccgacgcggtgaacgacaagatctcggac
gaggacatcctccgtatcgaggagaacgcctgtccgacctgtggctcctgctccggcatg
ttcaccgccaactcgatgaactgcctgaccgaggccatcggcctgtccctccccggcaac
ggctcggtgctcgccacccacacggcccgcaagggtctgtacgaggacgcggcccgcacg
gtggtcgagatcacgcaccgctattacgaccaggacgacgagtcggtcctgccccgcaac
atcgccacgcacgccgcgttcgagaacgccatggccctcgacatcgccatgggcggctcc
accaacacgatcctgcacctgctggccgccgcccaggaggcgggcgtccccttcggcctg
gacgagatcaacgaggtctcgcgccgcgtgccgtgcctcgccaaggtcgccccgaacgtc
gccaaggaccgcacgtactacatggaggacgtgcaccgggcaggcggcatccccgccctg
ctgggcgaactgcaccgcgcgggcctcctgaacgaggacgtccactcggtccacagcccg
tccctctccgactggctgaagacctgggacgtgcgcgccggctccccgtcccccgaggcg
atcgaactgtggcacgcggcccccggctgcgtccgctcctccgaggccttctcccagtcc
gagcgctgggaagccctcgacgaggacgccgagaacggctgcatccgctccgccgagcac
gcctactccaaggacggcggcctggcggtcctcaagggcaacctggcggtcgacggctgc
gtcgtgaagacggcgggcgtcgacgagtccatctggaccttcgagggccccgcggtcgtc
tgcgagtctcaggaagaggccgtcgacaagatcctccgcaaggagatcacgcacggcgac
gtcgtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctac
ccgacgtccttcctcaagggccgcggcctcggcaagacctgcgccctgatcaccgacggc
cgcttctccggcggcacctcgggcctgtccatcggccacgcctcccccgaggcggcctcc
ggcggcaccatcgccctggtccaggacggcgaccgcatccacatcgacatcccgaaccgc
tcgatcgaactcctggtctccgacgaggaactcgccacccgccgcagcgccctgaacggc
gtctacgcccccgcaaaccgcgaccgcaaggtctccgccgccctccgcgcctacgccgcg
atggcaacgagcgcggacaagggcgccgtacgagacgtttccaagctgggctga
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