Streptomyces mirabilis: SMIR_19545
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Entry
SMIR_19545 CDS
T10322
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
smib Streptomyces mirabilis
Pathway
smib00230
Purine metabolism
smib01100
Metabolic pathways
smib01110
Biosynthesis of secondary metabolites
Module
smib_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
smib00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SMIR_19545 (purL)
Enzymes [BR:
smib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SMIR_19545 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
FGAR-AT_PurM_N-like
Motif
Other DBs
NCBI-ProteinID:
QUW81042
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Position
4408459..4410717
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AA seq
752 aa
AA seq
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MSRTPLDTVENAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPQSDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMKHEDIHLAKASGTGNKVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSG
GMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLEICDKWDVIATVIGEVT
DGDRLEIYWHGGKIVDVDPRTVAHDGPVYERPYARPEWQDALQADDANKLPRPASSEELK
DQVLKLVSSPNQASKSWITSQYDHFVQGNTVLAQPEDSGMIRIDEETGLGVAIATDGNGR
YAKLDPYAGAQLALSEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAIRGLADAC
QQLGTPVTGGNVSLYNQTGEVAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTR
EEFGGSAWSQVVHDHLGGLPPKVDLERERLLGEILISASRDGMIDSAHDLSDGGLIQAVV
ESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEELRFNDMCGARGLPVTRIGV
VDGDAVEVQGEFALPLDELRTAHEGTIPALLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcacgcctctggacacggtcgagaacgcggccgcgacccccgacgtcgagctg
ccctgggccgaactgggcctgaagaaggacgagtacgagcgcgtcgtcgagatcctcggc
cgccggcccaccggcgccgagctcgccatgtactccgtcatgtggtccgagcactgctcg
tacaagtcctcgaaggtccacctccgccagttcggcgagaaggccccgcagtccgacgcc
ctgctcgtcggcatcggcgagaacgccggtgtcgtcgacgtcggccagggctacgccgtc
accttcaaggtcgagtcgcacaaccacccgtcgtacgtcgagccctaccagggagcggcc
accggcgtcggcggcatcgtgcgcgacatcatcgcgatgggcgcccgcccggtcgccgtc
gtcgacccgctgcgcttcggcgccgccgaccaccccgacaccaagcgcgtcctgccgggc
gtcgtcgcgggcatcggcggctacggcaactgtctcggtctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaaccccctcgtcaacgccggtgccatcggtgtc
atgaagcacgaggacatccacctcgcgaaggcgtccggcaccggcaacaaggtcatcctc
tacggggcccgcacgggcggcgacggcatcggcggcgcctccatcctggcgagtgagacc
ttcgacgacgccaagccgtcgaagcggcccgcggtccaggtcggcgaccccttccaggag
aagctgctcatcgagtgcacgctcgaggccttcgccgagaagctggtcgtcggcatccag
gacctcggcgcggccggtctgtcctgcgccacctccgagctggcctccaacggctccggc
ggcatgcgcgtcaccctggacgacgtaccgctgcgggactcgactctctctcccgaggaa
atcctcatgagcgagtcgcaggaacgcatgtgcgcggtcgtcgagccggagaaggtcgac
cggttcctggagatctgcgacaagtgggacgtcatcgccaccgtcatcggtgaggtcacc
gacggcgaccgtctggagatctactggcacggcggcaagatcgtcgacgtcgacccgcgc
acggtcgcccacgacggcccggtctacgagcgcccctacgcccgccccgagtggcaggac
gccctccaggccgacgacgcgaacaagctgccgcgcccggcgagcagcgaggagctcaag
gaccaggtcctcaagctcgtgagctcgccgaaccaggcctccaagtcctggatcacctcc
cagtacgaccacttcgtgcagggcaacacggtgctggcgcagcccgaggactcgggcatg
atccgcatcgacgaggagaccgggctcggcgtcgccatcgccacggacggcaacggccgc
tacgccaagctggacccgtacgccggcgcacagctcgccctctccgaggcctaccgcaat
gtcgcgacgaccggcgccaagccgctcgccgtctccgactgcctgaacttcggctcgccc
gaggacccggccgtcatgtggcagttcgccgaggccatccgcggtctcgccgacgcctgc
cagcagctgggcaccccggtgaccggcggcaacgtctcgctctacaaccagacgggcgag
gtcgccatccacccgaccccggtcgtggccgtgctgggcgtcatcgacgacgtcgcccgc
cgcacgccggtcgccttccaggaagagggccagctcctctacctgctcggtgacacccgt
gaggagttcggcggttcggcctggtcgcaggtcgtccacgaccacctcgggggcctgccc
ccgaaggtcgacctggagcgcgaacgcctcctcggcgagatcctcatctccgcgtcccgc
gacggcatgatcgactcggcgcacgacctgtccgacggcggtctgatccaggccgtggtc
gagtcggcgctgctcggcggcaagggcgcccggctggtcgtccccgacggtctcgacgcc
ttcaccttcctcttctcggagtcggcgggccgcgcggtcgtcgccgtcccgcgctcggag
gagctccgcttcaacgacatgtgcggtgcgcggggtctgcccgtcacccgtatcggtgtc
gtggacggagacgcggtcgaggtccagggcgagttcgcactcccgctggacgagctccgc
acggcccacgagggcacgatcccggcgctcctcgcctga
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