Streptomyces mirabilis: SMIR_25315
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Entry
SMIR_25315 CDS
T10322
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
smib Streptomyces mirabilis
Pathway
smib00790
Folate biosynthesis
smib01100
Metabolic pathways
smib01240
Biosynthesis of cofactors
Brite
Enzymes [BR:
smib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SMIR_25315
6.3.2.17 tetrahydrofolate synthase
SMIR_25315
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QUW82012
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Position
5736807..5738348
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AA seq
513 aa
AA seq
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MSELPPHDSSESDEPDPSDPHGLFDEIVAAETDRDPDLAVIAAGSRTLRAQGADAGRQAD
VPVRPADPEVDKALREVEAELAGRWGETKLEPSVSRIAALMDVLGEPQRAYPSIHITGTN
GKTSTARMIEALLGAFELRTGRYTSPHVQSITERISLDGAPIPAERFIETYNDIKPYIEM
VDAQQEYRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLD
HTDRLGETPGEIATEKAGIIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVV
ARQVAVGGQLITLRGLGGEYEEIFLPLHGPYQAHNAAVALAAVEAFFGVGAAHAQRLDID
TVRKAFASVTSPGRLEVVRRSPTVVLDAAHNPAGARATAEAVGEAFDFSRLIGVVGASGD
KNVRGLLEAFEPIFAEVVITQNSSHRAMDADELAGIAVEIFGDDRVQVEPRLDDAIEAAI
TLAEEEGEYAGGGVLVTGSVITVGEARLLLRRG
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagctccccccgcacgacagcagcgagtcagacgagccggatcccagcgacccg
cacggtctcttcgacgagatcgtcgcggccgagaccgaccgagaccccgacctcgcggtg
atcgcggccggcagccgcaccctgcgcgcccagggcgccgacgcgggccggcaggccgac
gtgcccgtgcgcccggccgaccccgaggtcgacaaggcgctgcgcgaggtggaggccgag
ctcgccggccgctggggcgagaccaagctggagccctccgtcagccggatcgccgcgctg
atggacgtcctgggcgagccccagcgcgcgtacccctcgatccacatcacgggcacgaac
ggcaagacctccaccgcccgcatgatcgaggccctcctcggcgccttcgagctgcgtacc
ggccggtacaccagcccccacgtccagtcgatcaccgagcggatcagcctcgacggcgcc
ccgatccccgccgagcggttcatcgagacgtacaacgacatcaagccgtacatcgagatg
gtcgacgcacagcaggagtaccggctgtcgttcttcgaggtgctcaccggcatggcgtac
gccgccttcgccgacgcccccgtcgacgtcgccgtcgtcgaagtcggcatgggcggcagc
tgggacgccaccaacgtgatcgacggtgacgtcgccgtcgtcacccccatcgacctcgac
cacaccgaccggctcggcgagacgcccggcgagatcgccaccgagaaggccggcatcatc
aagcaggacgcgaccgtgatcctggctcagcagccggtggacgcggcccaggtgctgctg
aagaaggccgtggaagtcgacgcgaccgtggcccgggagggcctggagttcggggtcgtc
gcccggcaggtcgccgtcggcgggcagctcatcacactgcgcgggctcggtggtgagtac
gaggagatcttcctgccgctgcacggtccctaccaggcgcacaacgccgccgtggcgctc
gccgcggtcgaggcgttcttcggtgtcggcgcggcgcacgcccagcggctcgacatcgac
accgtgcgcaaggccttcgcctccgtcacctcgccgggccgcctcgaggtcgtacggcgc
tcgccgaccgtcgtcctggacgccgcgcacaacccggcgggcgcccgtgccaccgccgag
gccgtgggcgaggccttcgacttcagccggctgatcggcgtcgtcggtgcgagcggcgac
aagaacgtgcgggggctgctcgaagccttcgagccgatcttcgccgaggtcgtgatcacc
cagaactccagccatcgcgcgatggacgccgacgagctcgccggtatcgccgtcgagatc
ttcggcgacgatcgggtgcaggtggagccgcggctcgacgacgcgatcgaggcggcgatc
acgctggccgaggaggagggcgagtacgcgggcggcggcgttctcgtgaccggctccgtc
atcaccgtcggcgaggcccgactgctcctgaggaggggctga
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