Streptococcus milleri: NCTC11169_01306
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Entry
NCTC11169_01306 CDS
T09563
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smie
Streptococcus milleri
Pathway
smie00300
Lysine biosynthesis
smie00550
Peptidoglycan biosynthesis
smie01100
Metabolic pathways
smie01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smie00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC11169_01306 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC11169_01306 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC11169_01306 (murF)
Enzymes [BR:
smie01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC11169_01306 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF7687
Motif
Other DBs
NCBI-ProteinID:
VEE12868
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Position
1:complement(1293840..1295210)
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AA seq
456 aa
AA seq
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MQLTFYEVASVLKAKNDVHQFPNCTFRNVEFDSRLIEEGDLFLPLKGARDGHDFIATAFE
NGAVATLSEKELDDYPSILVDDVLAALQRLAQYYLEKMKVDVFAVTGSNGKTTTKDMLAH
LLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKLVLEMGQDHMGDIHLLSTIAQPKVGI
VTLIGEAHLEFFKSRHEIAKGKMQIANGMKDGSLLIIPADKIINDFLPSQQSVVRFGPDE
DIFLTKLEERKDSLTFETNFLDNAIDLPVTGKYNATNAMIASYVALKEGVTQDKIQKAFA
TLELTRNRTEWKKAKNGADILSDVYNANPTAMRLILETFSTIPFNEKGRKLAVLADMKEL
GADSKQMHGAMITSLNPEILSEIFLYGEDMAALFAYAKEIFPPGKAHYFVKNAEKDQFSD
LVKAVKEALKPTDQLLIKGSNSMNLASLVEKLENEE
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgcaattaacgttctatgaagtagcttctgtattgaaagccaaaaatgatgttcatcaa
tttccgaattgtacatttagaaatgtagaatttgacagccgattgattgaagaaggggat
ttatttttgcctcttaaaggagcacgtgacgggcatgactttattgcgacagcatttgaa
aatggtgctgtggcaaccttgtcagaaaaagaattggacgactatccttctattttagtt
gatgatgtattggcagcgttgcagcgtttggcacagtattatctggaaaaaatgaaggta
gatgtctttgcggtcacaggttctaacggtaagacgacgaccaaagatatgctggctcac
ctcttgtcaacaacttacaagacttataaaacgcaaggaaactacaataatgaaattggt
cttccttatacggttttacacatgccagatgacaccgaaaaattggttttggaaatggga
caagatcacatgggggatattcaccttctgtccacgattgctcagccaaaagtaggtatt
gtgacgctgattggcgaagcgcatttagaattctttaaaagtcgtcatgaaattgcaaaa
ggaaaaatgcaaattgccaacggcatgaaagacgggagtcttttaatcattccagcggac
aagattatcaatgattttctaccgagccagcaaagtgtagtccgttttggtccagacgaa
gatattttcctaacgaaattagaagaacgaaaagatagtttgacttttgaaaccaatttc
ttagataacgctattgaccttccagtaactgggaagtacaatgcaacaaatgccatgatt
gcatcttatgtggcgttgaaagaaggagtaacacaagataagatccaaaaagcatttgcc
acgcttgaattaacacgaaatcgaaccgaatggaagaaagctaaaaatggtgcggatatc
ctctcagatgtttacaatgccaatccaaccgctatgcgattgattttggagacattttca
acgattccgtttaatgaaaaaggtcggaaactggcagttttagctgatatgaaagaattg
ggggctgattctaaacaaatgcacggtgccatgataaccagcctaaatccagaaattctc
tcagaaattttcctttatggagaggacatggctgctctatttgcctatgctaaggaaatt
ttcccgcctgggaaagcccattattttgtaaaaaatgctgaaaaagatcaattttctgac
ttagtcaaggctgttaaagaagcgctcaaaccaacggaccaattgctgataaaaggaagt
aattctatgaacttagccagtctagtggagaaattggagaatgaagagtaa
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