Streptococcus mutans LJ23 (serotype k): SMULJ23_0719
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Entry
SMULJ23_0719 CDS
T02086
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smj
Streptococcus mutans LJ23 (serotype k)
Pathway
smj00290
Valine, leucine and isoleucine biosynthesis
smj00620
Pyruvate metabolism
smj01100
Metabolic pathways
smj01110
Biosynthesis of secondary metabolites
smj01210
2-Oxocarboxylic acid metabolism
smj01230
Biosynthesis of amino acids
Module
smj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SMULJ23_0719 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMULJ23_0719 (leuA)
Enzymes [BR:
smj01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SMULJ23_0719 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IF-2
Motif
Other DBs
NCBI-ProteinID:
BAL69053
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All DBs
Position
773356..774921
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AA seq
521 aa
AA seq
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MRKVEFLDTTLRDGEQTPGVNFSIKEKVAIAKQLEKWGISDIEAGFPAASPDSFEAVKQI
AAAMTTTAVSGLARSVKSDIDACYEALKDAKFPQCHVFIATSPIHREFKLKKSKEEILEV
IKEHVTYARSKFDVIEFSPEDATRTELDFLLQVVQTAVDAGATYINIPDTVGFTTPVEFG
HIFKYLIENVKSDRDIIFSPHCHDDLGMATANTLAAIKNGAGRVEGTVNGIGERAGNVAL
EEVAVALNIREDYYDATSAIVLDETVTTSEMVSRFSGIPVPKNKAVVGGNAFSHESGIHQ
DGFLKNPLTYEIITPELVGVKKSSLPLGKLSGRHAFIEKLKELKLDFEEGEVAPLFAKFK
SLADKKHDITDADIRALVAGTSVENPEGFHFKDLRLTSNNDDTITAQVIMVNEGEEEVTI
IANGKGSVEAIFNAVDKFFNQTVKLDSYNIEAVTDGIDAQARVLVSVENVDTDTIFNASG
LDFDVLKASAIAYINANTFVQKENAGEIGHKVSERDYPSND
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgcgtaaggttgaatttcttgacacaacgctccgtgatggcgaacaaacaccgggggtt
aatttttcgattaaagaaaaagtagctattgccaagcaattggagaagtggggaatctct
gatattgaagccggttttccagctgctagccctgactcttttgaagctgtgaagcaaatt
gcagcagcgatgacaacgactgctgtatcaggtctggctcgttctgtgaaatctgatatt
gatgcctgttatgaggcacttaaggatgccaaatttccacaatgtcatgtctttattgca
accagtcctattcatcgtgaatttaagcttaaaaaatccaaagaagaaattcttgaagta
attaaggaacatgtaacttatgcgcgctcaaaatttgatgtgattgaattttcaccagag
gatgccacacgtacagaacttgatttcctattgcaggtagtgcaaactgctgtagatgct
ggtgctacttatattaatatccctgatacagttggctttaccacgccagtagaatttggc
catattttcaagtatctcattgaaaatgttaaatctgaccgtgacattattttcagccct
cattgtcatgatgacttgggaatggcaaccgctaataccctcgctgccattaaaaatggt
gctggacgtgttgaaggaacggttaatggtatcggagaacgtgctggtaacgtagctctt
gaagaagtggccgtagctcttaatattcgtgaagattactatgatgcgaccagtgctatc
gttcttgatgagacagtgaccacttcagaaatggtatcacgtttctcgggtattcctgtt
cctaaaaataaagctgttgttggtggcaatgctttttcacatgaatccggtattcatcaa
gatggttttcttaagaatcccctcacttatgaaattatcacgcctgaattggttggtgtt
aagaaaagttccctgccgcttgggaaattatctggccgtcatgcctttattgaaaaatta
aaagaattgaagcttgattttgaagaaggagaggttgcacctctttttgcaaaatttaaa
tcgttggccgataaaaaacacgatatcacagatgctgatattagagctttggtagcaggg
actagtgttgaaaatcctgaaggtttccactttaaggacttaaggctgacatcaaataat
gacgacacgatcacagcacaagttattatggtcaatgagggtgaggaagaagtaactatc
attgctaatggtaagggttctgttgaagctattttcaatgctgtcgataaattctttaat
caaactgttaagttagatagttataatattgaggctgttactgatggtattgatgctcag
gcacgtgtgctcgtttctgtggaaaatgttgatacggataccattttcaatgcttctggt
cttgactttgatgttttaaaagctagtgctattgcttatatcaatgctaatacctttgtt
caaaaggaaaatgctggtgaaattggtcacaaagtttcagaacgtgattatccaagtaat
gactag
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