KEGG   Streptococcus macedonicus: SMA_0034
Entry
SMA_0034          CDS       T01674                                 
Symbol
purH
Name
(GenBank) IMP cyclohydrolase/Phosphoribosylaminoimidazolecarboxamide formyltransferase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
smn  Streptococcus macedonicus
Pathway
smn00230  Purine metabolism
smn00670  One carbon pool by folate
smn01100  Metabolic pathways
smn01110  Biosynthesis of secondary metabolites
Module
smn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:smn00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SMA_0034 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SMA_0034 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:smn04147]
    SMA_0034 (purH)
Enzymes [BR:smn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     SMA_0034 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     SMA_0034 (purH)
Exosome [BR:smn04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   SMA_0034 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: CCF01325
LinkDB
Position
41037..42584
AA seq 515 aa
MTKRALISVSDKAGIVEFAQELKKLGWDIISTGGTKVALDKAGVDTIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDLDSHLQAAKDNHIELIDLVVVNLYPFKETILKPEVTYADAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSANGETSFETRQRLAAKVFRHTA
AYDALIAEYFTKQVGETKPEKLTITYDLKQPMRYGENPQQDADFYQKALPTDYSIASVKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYAYESDSV
SIFGGIVVLNREVDAATAKKMHAIFLEIIIAPSYSEEALEILTTKKKNLRILQLPFEAQE
ASQVEKEYTGVVGGLLVQNQDVVEENPADWKVVTKRQPNDQEKTALEFAWKAIKYVKSNG
IIVTNDHMTLGVGPGQTNRVASVRIALDQAKDRLDDAVLASDAFFPFADNVEEIAAAGVK
AIIQPGGSVRDQESIDMADKYGITMVFTGVRHFRH
NT seq 1548 nt   +upstreamnt  +downstreamnt
atgacaaaacgtgcactaattagtgtttctgataaagcgggtattgttgaatttgctcaa
gaattgaaaaaacttggttgggatattatctcgactggtggaacaaaagttgcgcttgat
aaagcaggtgttgacactatcgcgattgatgatgtgactggattcccagaaatgatggac
ggtcgtgtgaaaacacttcacccaaatattcatggcggtcttttggctcgtcgtgacctt
gacagccaccttcaagctgcaaaagataaccacattgaattgattgatcttgttgtggtt
aacctttacccattcaaagaaacaatcttgaaaccagaagtaacttacgctgatgcggtt
gaaaatattgatattggtggcccttcaatgcttcgctctgctgctaaaaaccatgctagt
gtaacagttgtcgttgatccagctgactatgctgttgttttggatgaattgtcagctaat
ggtgaaacaagctttgaaactcgtcaacgtttggcagcaaaagttttccgtcatacagca
gcttacgatgctttaattgcagaatatttcacaaaacaagttggtgaaacaaaacctgaa
aaactcacaatcacttacgatttgaaacaaccaatgcgttatggtgaaaatcctcaacaa
gacgctgatttctaccaaaaagctttgccaacagattactcaattgcttctgttaaacaa
ttgaatggtaaagaattgtcatttaacaacatccgcgacgctgatgctgcaatccgcatt
atccgtgatttcaaagaccgtccgacagttgttgcccttaaacacatgaatccatgtggt
attggacaagctgacgatattgaaacagcttgggactatgcttatgaatcagactcagtt
tcaatctttggtggaattgttgtacttaaccgtgaagttgacgccgcaacagctaagaaa
atgcacgctatcttccttgaaattatcattgcaccaagttattcagaagaagcccttgaa
atcttgacaactaagaagaaaaacttgcgtattcttcaattgccatttgaagctcaagag
gctagccaagttgaaaaagaatacactggtgttgtcggtggtcttttggttcaaaaccaa
gatgttgtcgaagaaaatccagctgattggaaagttgtgacaaaacgtcaaccaaatgac
caagaaaaaacagcgcttgaatttgcttggaaagctatcaaatacgtgaaatctaacggt
attattgtgacaaatgaccacatgacacttggtgttggtcctggtcaaacaaaccgtgta
gcttctgttcgtatcgctcttgatcaagccaaagaccgtcttgacgatgctgtccttgct
agtgatgccttcttcccatttgcagacaacgttgaagaaattgctgcagcaggtgtgaaa
gcaatcatccaacctggcggttcagttcgtgaccaagaatctattgatatggctgataaa
tacggcattaccatggtatttacaggtgttcgtcacttccgtcattaa

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