Streptococcus macedonicus: SMA_0613
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Entry
SMA_0613 CDS
T01674
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smn
Streptococcus macedonicus
Pathway
smn00300
Lysine biosynthesis
smn00550
Peptidoglycan biosynthesis
smn01100
Metabolic pathways
smn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMA_0613 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMA_0613 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMA_0613 (murF)
Enzymes [BR:
smn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMA_0613 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CCF01904
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Position
613314..614678
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AA seq
454 aa
AA seq
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MKLTLHEVAKVVGAKNTISEFDDVPLRQIEFDSRKIEKGDLFLPLKGARDGHDFIETAFE
NGAVATFSEREVAGHPYIWVDDCLEAFQALASYYLEKQRVDVIAVTGSNGKTTTKDMIAA
VLSTEYKTYKTQGNYNNEIGLPYTALHMPDDTEKIVLEMGQDHMGDIHLLSELAKPHIGV
VTLIGEAHLEFFGSREKIAEGKMQIVDGMDSDGILIAPADTIVDPYLPESQMVIRFGDGA
EIFVKDLQENKESLTFTTNVIDSPITLPVPGKYNATNAMVAAYVGKLLAISDDDIVEALE
TIELTRNRTEWKKAANGADILSDVYNANPTAMRLILETFSKIPANEGGKKIAVLADMKEL
GEQSVELHKRMIMSLSPETLDTLIFYGEDIAELAQLASQMFPIGKVYYFKKTADEDQFDA
MLETVQKVLQPADQILLKGSNSMQLAKVVEVLEK
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacattgcatgaagtcgccaaggttgttggcgctaaaaatactatttcggag
tttgatgacgttcccctgcgacaaattgaatttgacagtcgtaagattgaaaaaggggat
ttatttttaccattaaaaggtgcgcgtgatgggcatgattttattgaaactgcctttgaa
aatggtgctgttgcaactttttcagagcgtgaagtagctggtcatccatacatttgggtt
gatgattgtctagaggcttttcaagcgctagctagctattatcttgagaaacagcgtgtt
gatgttattgctgtgacagggtcaaatggtaaaacgacaaccaaagatatgattgctgcg
gttttatcaacagaatacaagacttataaaacacaaggcaactacaataacgaaattggt
ttgccatatacagcacttcatatgccagatgatacggagaaaattgtccttgaaatgggg
caagatcatatgggtgacattcatctgttgtcagaacttgcaaaaccacatatcggtgtg
gtgactttgattggtgaagctcatttggaatttttcggtagtcgtgagaaaatcgcagaa
ggtaaaatgcaaattgttgatggcatggattcagatggcattttgattgcgccagctgac
acaattgttgatccttatttacctgaaagccaaatggttattcgttttggtgacggcgca
gaaatttttgtgaaagatttgcaagaaaataaggaatcgttgacctttacgacaaatgtg
attgacagtccaattaccctacctgtgcctggaaaatacaatgcgactaatgccatggtg
gcagcttatgttggtaaattattagccatttctgatgacgatattgtcgaggctcttgag
acaatcgaattaacgcgcaatcgtacggaatggaaaaaagcagccaatggtgctgatatt
ttgtcagatgtttacaatgctaatccaacggcaatgcgcttgattttagagacattttca
aaaattcctgctaatgagggcggtaaaaaaatcgctgtacttgctgacatgaaagaattg
ggtgagcaatctgttgagcttcataaacgcatgattatgagcttgtcacccgaaacatta
gatacactcattttctatggggaagacattgccgagttggcacaacttgctagtcaaatg
ttcccaattggaaaagtttattatttcaagaaaacagctgacgaggatcaatttgatgcc
atgcttgaaactgtccaaaaagtattgcaaccagctgaccaaatcttgttgaaaggtagc
aactcaatgcagttagctaaagttgttgaagtattggagaaatag
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