Streptococcus mutans UA159 (serotype c): SMU_1384
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Entry
SMU_1384 CDS
T00100
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smu
Streptococcus mutans UA159 (serotype c)
Pathway
smu00290
Valine, leucine and isoleucine biosynthesis
smu00620
Pyruvate metabolism
smu01100
Metabolic pathways
smu01110
Biosynthesis of secondary metabolites
smu01210
2-Oxocarboxylic acid metabolism
smu01230
Biosynthesis of amino acids
Module
smu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SMU_1384 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMU_1384 (leuA)
Enzymes [BR:
smu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SMU_1384 (leuA)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IF-2
LIC_12936
Motif
Other DBs
NCBI-ProteinID:
AAN59051
UniProt:
Q8DTG2
LinkDB
All DBs
Position
complement(1311947..1313512)
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AA seq
521 aa
AA seq
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MRKVEFLDTTLRDGEQTPGVNFSIKEKVAIAKQLEKWGISDIEAGFPAASPDSFEAVKQI
AAAMTTTAVSGLARSVKSDIDACYEALKDAKFPQCHVFIATSPIHREFKLKKSKEEILEV
IKEHVTYARSKFDVIEFSPEDATRTELDFLLQVVQTAVDAGATYINIPDTVGFTTPVEFG
HIFKYLIENVKSDRDIIFSPHCHDDLGMATANTLAAIKNGAGRVEGTVNGIGERAGNVAL
EEVAVALNIREDYYDATSAIVLDETVTTSEMVSRFSGIPIPKNKAVVGGNAFSHESGIHQ
DGFLKNPLTYEIITPELVGVKKSSLPLGKLSGRHAFIEKLKELKLDFEEGEVAPLFAKFK
SLADKKHDITDADIRALVAGTSVENPEGFHFKDLRLTSNDDDTITAQVIMVNEGEEEVTI
IANGKGSVEAIFNAVDKFFNQTVKLDSYNIEAVTDGIDAQARVLVSVENIDTDTIFNASG
LDFDVLKASAIAYINANTFVQKENAGEIGHKVSERDYPSND
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgcgtaaggttgaatttcttgacacaacgctccgtgatggcgaacaaacaccgggggtt
aatttttcgattaaagaaaaagtagctattgccaagcaattggagaagtggggaatctct
gatattgaagccggttttccagctgctagccctgactcttttgaagctgtgaagcaaatt
gcagcagcgatgacaacgactgctgtatcaggtctggctcgttctgtgaaatctgatatt
gatgcctgttatgaggcgcttaaggatgccaaatttccacaatgtcatgtctttattgca
accagtcctattcatcgtgaatttaagcttaaaaaatccaaagaagaaattcttgaagta
attaaggaacatgtaacttatgcgcgctcaaaatttgatgtgattgaattttcaccagag
gatgccacacgtacagaacttgatttcctattgcaggtagtgcaaactgctgtagatgct
ggcgctacttatattaatatccctgatacagttggctttaccacgccagtagaatttggc
catattttcaagtatctcattgaaaatgttaaatctgaccgtgacattattttcagccct
cattgtcatgatgacttaggaatggcaaccgctaataccctcgctgccattaaaaatggt
gctggacgtgttgaaggaacggttaatggtatcggagaacgtgctggtaacgtagctctt
gaagaagtggccgtagctcttaatattcgtgaagattactatgatgcgaccagtgctatc
gttcttgatgagacagtgaccacttcagaaatggtatcacgtttctcgggtattcctatt
cctaaaaataaagctgttgttggtggcaatgctttttcacatgaatccggtattcatcaa
gatggttttcttaagaatcccctcacttatgaaattatcacgcctgaattggttggtgtt
aagaaaagttccctgccgcttgggaaattatctggccgtcatgcctttattgaaaaatta
aaagaattgaagcttgattttgaagaaggagaggttgcacctctttttgcaaaatttaaa
tcgttggccgataaaaaacacgatatcacagatgctgatattagagctttggtagcaggg
actagtgttgaaaatcctgaaggtttccactttaaggacttaaggctgacatcaaatgat
gacgacacgatcacagcacaagttattatggtcaatgagggtgaggaagaagtaactatc
attgctaatggtaagggttctgttgaagctattttcaatgctgtcgataaattctttaat
caaactgttaagttagatagttataatatcgaggctgttactgatggtattgatgctcag
gcacgtgtgctcgtttctgtggaaaatattgatacggataccattttcaatgcttctggt
cttgactttgatgttttaaaagctagtgctattgcttatatcaatgctaatacctttgtt
caaaaggaaaatgctggtgaaattggtcacaaagtttcagaacgtgattatccaagtaat
gactag
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