Streptococcus mutans UA159-FR: SMUFR_0225
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Entry
SMUFR_0225 CDS
T03797
Symbol
gshA
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
smua
Streptococcus mutans UA159-FR
Pathway
smua00270
Cysteine and methionine metabolism
smua00480
Glutathione metabolism
smua01100
Metabolic pathways
smua01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
smua00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SMUFR_0225 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SMUFR_0225 (gshA)
Enzymes [BR:
smua01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SMUFR_0225 (gshA)
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
GARS_A
Dala_Dala_lig_C
ATPgrasp_ST
ATP-grasp_4
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AJD54700
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All DBs
Position
complement(257156..259420)
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AA seq
754 aa
AA seq
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MHINQLLQHANSDLPLLQANFGLERESLRINKTNHRLAQTPHPTALGSRQFHPYIQTDYS
ESQMELITPVAHSSKEVLRFLGAITDVAERSIDQNQYLWPLSMPPQITEDEIEIAQLEDD
FEFSYRQYLDKKYGKILQSISGIHYNMELGADLMNELFELSGYQSFIDFKNDLYLKVAQN
FLNYRWFLTYLYGASPLAEKGFLNEELSQTVRSIRNSHLGYVNTDDIKVPFDSLENYISS
IEHYVKSGALSAEKEFYSAVRLRGSKHNRDYLTKGITYLEFRCFDLNPFNNRGITQETID
SVHLFILAMLWLDTPKKLNQALDKAQKLNDKIALSHPLEKLPKENSASLIIEAMEALIKH
FKLPSYYDDLLIAIKKQVENPKLTLSGRLFEHIKHASLEHFGQKKGQDYHNYAWQNYYAL
KGYENMELSTQMLLFDTIQKGIHFEILDENDQFLKLWHNDHIEYVKNGNMTSKDNYVIPL
AMANKVVTKKILRENGYPVPAGAEFDNKDEALRYYSQIKNKPIVVKPKTTNFGLGISIFE
TAASHNDYEKALDIAFIEDYSVLVEEFIPGTEYRFFILDGKCEAVLLRVAANVVGDGHST
VRQLVAQKNRDPLRGREHRSPLEIIDLGDIELLMLQQEGYTLEDILPKGKKVNLRGNSNI
STGGDSIDVTETMDPSYKQLAANMATAMGAWVCGVDLIIPDTNLKASKGKPNCTCIELNF
NPSMYMHTYCYQGPGQVITGKILAKLFPEISTKI
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atgcacatcaatcaattattacagcatgcaaattctgacttaccccttcttcaagctaat
tttggtttagaaagagaaagtctccgtatcaataaaacaaatcaccggctggctcagaca
cctcatccaacagcactgggttctcgccagtttcatccttatattcaaacagattacagt
gagtctcagatggaactaatcacgcctgtcgctcattccagcaaggaagtccttcgtttt
ttaggggctattactgatgttgcagagcgcagtattgaccaaaaccaatacctttggcct
ttgtctatgccgcctcaaattacagaagacgaaattgaaattgcccagttagaagatgac
tttgaattttcctatcgtcagtatttagataaaaaatatggaaaaatcctgcaatccata
tctggcattcattataacatggagctaggtgctgatttaatgaatgaactttttgaactt
agcggttatcagtctttcattgactttaaaaatgatctctacttaaaagtggctcagaat
ttcttaaactatcgttggttcctgacctacctttatggggctagtcccttggctgaaaaa
ggatttttaaatgaagagctcagccaaactgttcgctcaatccgaaacagtcatttaggc
tatgtcaatactgatgatattaaggttcctttcgacagtctcgaaaattatatctcaagt
attgagcactacgttaaaagcggtgctctatcagctgaaaaagaattctattcagctgtt
cgtttgcgtggcagtaagcataatcgtgactatcttactaaaggaatcacttatttagaa
tttcgctgttttgatcttaatcccttcaataatcgcggcattacgcaagaaaccattgac
agtgtccatctctttatcttggccatgctctggcttgacacaccaaaaaagctgaatcaa
gcacttgataaggctcaaaaacttaatgataaaattgcattaagccatcctctggaaaaa
ttaccaaaggagaactctgcttcccttattatagaagcaatggaagccttaattaaacac
tttaaattaccaagttactatgatgatttactaattgctatcaaaaaacaagttgaaaat
cctaagttaactctaagcggccgtctctttgagcatattaagcatgcctcattggagcat
tttggacagaaaaaagggcaagattatcataactacgcttggcaaaattattatgccctc
aagggctatgaaaatatggaattgtcaacacaaatgctgctttttgataccatccaaaaa
ggaattcattttgaaattttagatgaaaatgatcaatttctcaaactgtggcataatgat
catattgaatatgtcaaaaatggcaacatgacttctaaagataactacgttatcccccta
gccatggccaataaagtggtgactaaaaaaatactaagagaaaacggctaccctgtccca
gcaggagctgaatttgacaataaagacgaggccctccgctattattcccaaatcaaaaat
aaacctattgttgttaaacctaagacaaccaatttcggacttgggatttctatttttgaa
acagcagccagtcacaatgattacgaaaaagcacttgacattgcctttattgaagactat
tcggtccttgtggaagaatttataccaggaacagaataccgtttcttcattctggacggt
aaatgtgaggccgttctcttgcgggttgcggccaacgtcgttggagacggccatagtact
gttcggcagctcgtggcacaaaaaaatagggatcctcttcgtggtcgggagcatcgctct
ccacttgaaatcattgatctcggtgatattgaattgctgatgctgcagcaagaaggttat
accctagaagacatcttaccaaagggcaagaaggtgaatcttcgtggtaattccaatatc
tcaactggcggcgattcgattgatgtgacagaaaccatggatcctagctacaaacaacta
gcagctaatatggcgacagcaatgggagcttgggtttgtggggtggatttgatcattcca
gataccaacttaaaagccagcaagggaaagccaaactgtacctgcattgagctcaatttc
aatccatccatgtatatgcatacctattgctaccaaggaccgggacaagttatcacaggc
aaaattctagccaagctctttcctgaaataagcaccaagatataa
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