Streptococcus mutans UA159-FR: SMUFR_0523
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Entry
SMUFR_0523 CDS
T03797
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smua
Streptococcus mutans UA159-FR
Pathway
smua00300
Lysine biosynthesis
smua00550
Peptidoglycan biosynthesis
smua01100
Metabolic pathways
smua01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smua00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMUFR_0523 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMUFR_0523 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMUFR_0523 (murF)
Enzymes [BR:
smua01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMUFR_0523 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AJD54998
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Position
560849..562207
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AA seq
452 aa
AA seq
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MKLTLQEIASVVGAQNDVSLFEDLTINAIEFDSRQIKTGDLFLPLQGARDGHEFIDTAFA
NGAVATFSEKNITSDYPYILVVDCLKAFQDLAQYYLEKMRVDVIAVTGSNGKTTTKDMIA
TILATTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHLGDIALLSNLTHPHIA
VVTLIGEAHLEFFGSREKIAEGKMQITQGMDGHGILIAPADKIINSFLPEKQKVIRFGAD
EDIFVTELEEHKNYLNFKTNFLDNEIKLPVTGKYNATNAMIASYVGKLLNVSEEKIISAL
AQLNLTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSSIPANNGGKKIAVLADMKE
LGDSELALHAAMIASLDPAVIDRIFLFGPLMQALADEVAQVYSVGKWYYFAQADQVDELT
EQIQKVLGPNDQILLKGSNSMKLAQVVECLEG
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaagttaactttacaagagatagcctcggttgtaggtgctcaaaatgatgtcagtctt
tttgaagatcttaccatcaatgctattgaatttgacagccgccagataaagacaggtgat
ttatttttacctctacagggtgcgcgtgatggccatgagtttattgatactgcttttgcc
aatggtgctgttgctactttttccgaaaaaaacataaccagtgattatccctatatttta
gttgtagattgcttgaaagcttttcaggatttggcgcaatactatttggagaaaatgcgg
gttgatgttattgctgtaacaggatctaacggaaaaacaaccacaaaggacatgatagca
actattttagcaactacttacaaaacttacaagacacaaggtaattataataatgaaatt
ggtctgccttatacagttttacacatgcctgatgatactgaaaaaattgtacttgaaatg
ggtcaggaccatctcggtgatattgcccttctgtctaatcttacccatcctcacatagct
gttgtcaccttgattggtgaagctcatttagagttctttggcagccgtgagaaaattgct
gaaggaaaaatgcaaattactcaaggaatggatggtcatgggattcttattgcaccagcg
gataaaatcattaattcatttttaccagaaaagcaaaaggttattcgctttggagctgat
gaagatatttttgtgaccgaattagaagagcataaaaactatttgaactttaaaacgaat
ttcctagataatgagattaaattgccagtaactggtaaatataatgctaccaatgctatg
attgctagctatgttggaaaactgcttaatgtctctgaagaaaagattatctctgcactg
gctcagctcaatctaactcgtaatcgaacggaatggaaaaaagcggctaacggtgcagat
atcttatctgatgtttataatgctaatccaacagctatgaaactgattttggagactttc
tccagcattccagcaaataatggtggtaaaaaaattgcggtgctggcagatatgaaagaa
ttaggagacagtgaattagccttacatgcagccatgattgctagtctagatcctgcagtg
atagatcgtatttttctttttggaccactaatgcaagctctagcagatgaagtcgcccaa
gtttattcagtagggaaatggtattattttgcccaagctgatcaggtagatgagctcact
gagcaaattcaaaaggtattaggccctaatgaccaaatacttctaaagggatcaaattcc
atgaaattggcccaagttgtggagtgtttggaagggtaa
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