Sulfurospirillum multivorans: SMUL_1563
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Entry
SMUL_1563 CDS
T03049
Symbol
cobA_hemD
Name
(GenBank) uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
smul
Sulfurospirillum multivorans
Pathway
smul00860
Porphyrin metabolism
smul01100
Metabolic pathways
smul01110
Biosynthesis of secondary metabolites
smul01120
Microbial metabolism in diverse environments
smul01240
Biosynthesis of cofactors
Module
smul_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
smul_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
smul_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
smul00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SMUL_1563 (cobA_hemD)
Enzymes [BR:
smul01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SMUL_1563 (cobA_hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SMUL_1563 (cobA_hemD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
AHJ12823
UniProt:
A0AA86ANR8
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Position
1520165..1521682
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AA seq
505 aa
AA seq
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MKTGKVYIAGAGCGDFELMTLKLKMLIEEAECIIYDRLVNKEILALAPKSAELIYYGKDN
CEGGLIQEKINATLIEKAKEGKNVLRLKGGHPFVFGRGGEEALDLVDAGIEFEIIPGVTS
AISVPAYAGIPISHRGINTSFHVFTGHSKDDGEKIDFETVSKLSGTLVFLMGIKNIEMIT
SNLVNFGKISSTPVAVIENGSTCHQRTVVGNLETISKIVEENHIQSPSIIIIGDVVNLRE
KLAWFEHKALHGHKVLVTSEKTQAKVTSRLVRSLGGESVECPFFTLDKKSFTIPRLINFD
TVLFTSPQSLHAFFEKIEDIRQLLHLRIGVAGEKTKEALNTYKLQANIYSNSYRTQELLN
LLTEKEEKVLLVRSTSISAELAVYSQSITELETYYVDKVLRSDEEVIAYINDVDIIAFPN
ACTVKTLIDSVGREILATKLIIASNENTALKIKSYGLHVNAFGNGEITEETFKTCMETEH
CIKGKKDGVVNRRNKGFTHSARAAS
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacaggaaaagtatatatcgcaggtgcaggttgtggagattttgaattgatgaca
ttaaaactcaagatgttgattgaagaagcagagtgtattatttatgatcgtcttgttaat
aaggaaattcttgcgttagcacccaaaagtgccgaacttatttattatggtaaagataat
tgcgaaggcggccttatccaagaaaaaattaatgcaacattaatcgaaaaagccaaagag
ggcaagaatgttttacgccttaaaggaggacacccttttgtctttggacgaggtggggaa
gaggccttggacttagtagatgcaggcatagaatttgaaattattccaggtgttacttct
gctatttcagtacccgcttatgcaggcattcctataagccatagaggtatcaatacatca
tttcatgtttttacaggacatagtaaagatgatggagaaaaaattgactttgaaacagta
tccaagctgagtggcactttagtttttttaatgggtattaaaaatatagagatgatcact
tcaaatcttgtaaattttggaaaaatatcatccacacctgttgcagtaattgaaaatgga
tcgacatgtcatcaacgaacggttgtcggaaacctagaaactatttcaaagattgttgaa
gaaaatcatattcagtcaccttctatcattattataggtgatgtagtaaatttacgcgaa
aaacttgcttggtttgagcataaagcattgcacgggcataaggttctggtaacatcagaa
aaaacccaagcaaaagtgacttcacggttggtccgaagtttaggtggagagagtgtagaa
tgtcctttttttacattagataaaaaatcgtttactattccaagacttattaattttgat
actgtgctctttacaagccctcaaagtttacatgctttttttgaaaaaatagaagatata
cgccagttacttcatttgcgtattggtgtggccggcgaaaaaactaaagaagcattaaac
acgtataaattacaagccaatatttattcgaacagctatcgcacacaagagttgcttaat
ctcttaactgaaaaagaagagaaagtacttttagtcagatctacctcaatttcagcagaa
cttgctgtatattctcaatctattactgaacttgagacctattatgttgataaagttttg
cgaagtgatgaagaagtaattgcttatatcaatgatgtcgatattatcgcttttcctaat
gcatgtacggttaaaacattaatagatagtgtagggcgtgaaatattagccaccaaatta
attattgcttcaaatgaaaatacagcattaaaaatcaagtcttatggtttacatgtaaac
gcttttggcaatggtgaaatcacagaagaaacatttaaaacatgcatggaaacagagcat
tgtatcaaagggaaaaaagatggtgtggttaatcggaggaacaaaggattcacgcattct
gctcgagcagctagttga
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