Sinorhizobium meliloti SM11: SM11_chr0781
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Entry
SM11_chr0781 CDS
T01885
Symbol
leuA2
Name
(GenBank) putative 2-isopropylmalate synthase protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smx
Sinorhizobium meliloti SM11
Pathway
smx00290
Valine, leucine and isoleucine biosynthesis
smx00620
Pyruvate metabolism
smx01100
Metabolic pathways
smx01110
Biosynthesis of secondary metabolites
smx01210
2-Oxocarboxylic acid metabolism
smx01230
Biosynthesis of amino acids
Module
smx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SM11_chr0781 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SM11_chr0781 (leuA2)
Enzymes [BR:
smx01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SM11_chr0781 (leuA2)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
EF-hand_14
TRIP13_N
Motif
Other DBs
NCBI-ProteinID:
AEH78059
UniProt:
F7X0S3
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All DBs
Position
814953..816569
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AA seq
538 aa
AA seq
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MTRERIYLFDTTLRDGQQTPGIDFSVEDKIAIASLLDQFGMDYVEGGYPGANPTDTEFFK
CRRTDKASFVAFGMTKRAGVSASNDPGLSALLSAKSDAICLVAKSWDYHVEVALGCTNEE
NLDNIRASVEAVVASGREAMVDCEHFFDGYKANSAYALACAKTAFEAGARWVVLCDTNGG
TQPPEIREIVSAVIAEGVPGANLGIHAHNDTGQAVANSLAAVEAGVRQIQGTLNGIGERC
GNANLVTLIATLALKETYSSRFETGIDAERLQELTKLAHAFDELLNRSPDPQAPYVGASA
FATKAGIHASALLKDPRTYEHVAPESVGNLRKVMVSDQGGKANFINALKRRGITVSKDDP
RLDKLISIVKEREATGYAYEGADASFALLASRILGTVPDFFRVESFRVMVERRFDANGKL
KTVSEAVVRVIVDGETMMSVAEGHGPVNALDLALRKDLGKYQSEIADLELADYKVRILNG
GTEAVTRVLIESTDRSGARWWTVGVSDNIIDASFQALMDSIVYKLLKNRDQVGSIAAE
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggaacgcatctatctcttcgacacgacgcttcgggacgggcagcagacgccc
ggcatcgacttttccgtcgaggacaagatcgcgattgcgtcgctgcttgatcaattcggc
atggattatgtcgagggcggatatcccggcgccaatcccacggatacggagttcttcaag
tgccggcgcaccgacaaggcctccttcgtcgccttcggcatgaccaagcgcgccggcgtc
tccgcctccaacgacccgggcctgagcgcgctgctgagcgccaagagcgatgcgatctgt
cttgtcgccaagagctgggattatcatgtcgaggtggcgctcggctgtacgaacgaggaa
aatctcgacaatatccgcgcttccgtggaggcggtcgtggcttccggccgcgaggcgatg
gtcgattgcgagcatttcttcgacggctacaaggcgaactccgcctatgcgctcgcctgc
gcgaaaacggctttcgaggccggcgcgcgctgggtcgtgctttgcgacacgaatggcggc
acgcagcctcccgagatccgcgagatcgtctcggccgtgattgcggagggagtgcccggt
gcaaatctcggcatccatgcgcataatgatacggggcaggcggtggccaactcgctggct
gcggtggaagccggcgttcgtcagatccagggcacgctcaacggcatcggcgaacgctgc
ggcaatgccaatctcgtgacgctgattgcgacgcttgccctgaaggaaacctattcgagc
cgtttcgagacgggaatcgatgccgagaggctccaggaactgaccaagctcgcccatgcc
ttcgacgagttgctcaaccgctctccggatccccaggccccctatgtcggcgcttcggct
tttgccaccaaggccggcattcacgcctccgcgttgctcaaggatccgaggacctacgag
catgtcgcgccggaaagcgtcggcaacctgcgcaaggtcatggtctccgatcagggaggc
aaggccaacttcatcaatgctctcaagcggcgcggcatcacggtctccaaggacgatccg
cggctcgacaagctgatctcgatcgtcaaggaacgcgaggcgacgggctatgcctatgaa
ggtgcggatgcgagcttcgcgctgctcgcgagccgcattctcggcaccgtgcccgatttt
ttccgggtggagagcttccgggtaatggtcgagcgccgcttcgacgcgaacggcaagctg
aagacggtatcggaggccgtggtcagggtgatcgtcgacggcgaaacgatgatgtcggtc
gccgaggggcatggcccggtcaacgcgctcgacctcgcgcttcgcaaggatctcggcaag
taccagtccgagatcgccgatctggaacttgccgattacaaggtgcgcatcctcaacggc
ggcaccgaggccgtcacccgcgtcctgatcgaatcgacggaccgctcaggggcgcgctgg
tggacggtcggcgtatccgacaacatcatcgacgcctcatttcaggcattgatggacagt
atcgtctacaagctgctcaaaaaccgcgatcaggtcggatcgatcgcggccgagtag
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