Stenotrophomonas maltophilia D457: SMD_0640
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Entry
SMD_0640 CDS
T02061
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smz
Stenotrophomonas maltophilia D457
Pathway
smz00300
Lysine biosynthesis
smz00550
Peptidoglycan biosynthesis
smz01100
Metabolic pathways
smz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMD_0640 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMD_0640 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMD_0640 (murF)
Enzymes [BR:
smz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMD_0640 (murF)
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Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF8011
Motif
Other DBs
NCBI-ProteinID:
CCH11225
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Position
737861..739255
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AA seq
464 aa
AA seq
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MKRTLLSLIAHWAGGEIHGDDVAIDAVSNDTRNLGPGSLYVALRGERFDGHDFAADAQAR
GASALLVERLLPVELPQVLVADSELALAKIATGMQRDRGTEVFAITGSNGKTSVKSLLLS
ILQQVAQHAHKVVYANPGNRNNEIGLPLAVIDAPEDADYAVYEMGAGKPGDIAYLTEIAR
PRYALVNNIAPAHLERMGSLLGVAVTKGAIYAALPADGVAVINADDAYGRWFEQHFISTP
ARCRVLRYGLEHSADVTARDIRAGAQGSQFTLVAPAGEARVVLGLPGRHNVSNALAAASL
ALAAGVGLALIAAGLAEAQPVPGRQIAHQLRNGAVLVDDSYNANPGSLAAAIDALAAAPE
EGWLVLGDMRELGPDAEALHAQAGLRARAAGLKRLYALGPLSAAAASAFGEGGRHFATHD
ALSQALKDELHAGVRCLVKGSRGSAMDTIVKALLAQGEESPHVV
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaccctgctttcgctgatcgcacactgggccggtggcgagatccacggcgac
gacgtggccatcgatgcggtcagcaatgacacccgcaatctcggtccgggcagtctgtat
gtggcgctgcgcggcgagcggttcgacggccatgacttcgcggccgacgcgcaggcgcgc
ggtgccagtgcgctgctggtcgagcgcctgctgccggtcgaactgccgcaggtgctggtg
gccgacagcgaactggcgctggcgaagatcgccacaggcatgcagcgtgaccgtggcacc
gaggtgttcgcgatcaccggcagcaatggcaagaccagcgtgaagagcctgctgctgtcg
atcctgcagcaggtggcccagcacgcgcacaaggtggtctacgccaacccgggcaaccgc
aacaacgagatcggcctgccgctggcggtgatcgatgcgccggaagatgccgactacgcc
gtctacgagatgggcgccggcaagccgggcgacatcgcctacctgaccgagatcgcccgc
ccgcgttatgcgctggtcaacaacatcgccccggcgcacctggaacgtatgggcagcctg
ctcggcgtggcggtgaccaagggcgcgatctacgccgcgctgccggccgatggcgtggcg
gtgatcaacgccgacgatgcctatggccgctggttcgaacagcatttcatcagcaccccg
gcgcgttgccgcgtgctgcgctatggcctggaacactcggcggacgtgaccgcgcgcgat
atccgcgccggtgcgcagggcagccagttcactctggtcgcaccggccggcgaagcccgc
gtggtgctgggcctgccgggtcgccacaacgtcagcaatgcgctggccgccgccagcctg
gcgctggccgccggtgtcggtctggcgctgattgccgccggcctggccgaagcgcagccg
gtgccgggtcgccagatcgcccatcagctgcgcaatggcgcggtgctggtggatgacagc
tacaacgccaaccccgggtcgctggccgcggccatcgatgccctggccgcggcgccggaa
gagggctggctggtgctgggcgacatgcgcgagctgggcccggacgcggaagcgctgcat
gcgcaggccggcctccgcgcacgtgctgccggcctgaagcgcctgtatgcactgggcccg
ctcagcgccgctgccgcctccgccttcggcgaaggcggccgccatttcgccacccacgac
gcgctgtcgcaggcgctgaaggacgagctgcacgccggcgtgcgctgcctggtcaagggt
tcccgtggcagcgccatggacacgattgtcaaagcgctgctggcgcaaggagaggaatcc
ccgcatgttgtatga
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