Streptococcus pneumoniae TCH8431/19A (serotype 19A): HMPREF0837_10334
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Entry
HMPREF0837_10334 CDS
T01259
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
snc
Streptococcus pneumoniae TCH8431/19A (serotype 19A)
Pathway
snc00230
Purine metabolism
snc01100
Metabolic pathways
snc01110
Biosynthesis of secondary metabolites
Module
snc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
snc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HMPREF0837_10334
Enzymes [BR:
snc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HMPREF0837_10334
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
ADI68562
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Position
308938..312663
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AA seq
1241 aa
AA seq
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MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLVEDLFAPAEKHIF
SEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQL
YLVNKDIDATELKAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYTAEDF
ARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHIDF
SASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGAAPKGNVVREKPEAGDVIILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLNG
TEIAISESQERMAVVVRPEDVDTFVAECNKENIDAVVVATVTEKPNLVMHWNGETIVDLE
RRFLDTNGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDC
SVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYA
VIEATARLVAAGANWSKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLVAFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIK
KNFAQFEASQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFV
FTSPEEIAGVEKIGQTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVP
AVVSDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKS
VETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGIC
NGFQALVKSGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDI
HAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSK
NGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggataaacgtatttttgttgaaaaaaaggctgattttcaggtcaagtcagagagtttg
gttagagagctccagcacaacttgggactgtcaagcttgaaaagtattcgtattgtgcaa
gtatatgatgtatttgacttggttgaggacttgtttgcacctgcagagaagcacattttc
tctgagcaggtaaccgaccatgttttagatgaagtatctgtgcaggcggatcttgctaac
tatgctttctttgccattgaaagtctaccagggcagtttgaccagcgtgcagcttcgtca
caggaagccttgcttttgttgggaagttcgagtgacgtgacagtcaacacagcccaactt
tacttggtgaataaagatattgatgcgactgagttgaaagctgtcaaaaactacctgctc
aatccagttgattctcgtttcaaggatatcacgacagggattgccaagcaggagttttca
gagtcagacaagaccattccaaaattgactttctttgaaagctatacagcagaagatttt
gctcgctacaaggccgaacaagggatggccatggaagtggatgatttgctctttatccaa
gactactttaagtcaatcgggcgcgtgccaactgagactgaacttaaggttttggacact
tactggtctgaccactgccgtcatacgacttttgagacagagttgaaacacatcgacttt
tcagcttctaaatttcaaaagcaattgcagtcaacctatgacaagtatattgccatgcgc
gaggaattaggtcggtctgaaaaaccacaaaccttgatggatatggcgactattttcggt
cgttatgagcgtgctaatggacgattggatgatatggaagtctctgacgaaatcaatgcc
tgctcagttgaaattgaagtggacgttgatggtgtcaaggaaccttggctcctcatgttt
aaaaacgaaacccacaaccatccaacagaaattgagccatttggtggagcggctacctgt
attggtggagctattcgtgatccgttgtcaggccgttcctatgtttaccaagccatgcgt
atttcaggtgctggtgatattacagcaccgatttcggaaactcgcgctgggaaattgcca
caacaagtcatttctaaaacagcagctcatggttattcttcatatggtaaccagattggg
cttgccacaacctacgttcgtgaatacttccacccaggctttgtagctaaacgtatggaa
cttggtgccgttgttggtgcggctcccaagggcaatgttgtccgtgaaaaacctgaagca
ggtgatgtgatcatccttctcggaggtaaaacaggtcgtgatggtgtcggtggtgcgacg
ggctcttctaaggttcaaacagttgagtctgtagagactgctggtgctgaggttcaaaaa
ggaaatgccatcgaagaacgcaagattcagcgcctcttccgtaatggcaatgtcactcgt
ctgatcaagaagtccaatgactttggggcaggcggtgtctgtgtggctatcggtgaattg
gcagacggtcttgaaatcgacctcaacaaggtgcctcttaaataccagggcttgaatggt
acagaaattgccatctctgaatcacaagaacggatggcggtcgtggttcgtcctgaagat
gtggataccttcgttgccgaatgtaacaaagaaaatattgatgctgttgtggtggcgaca
gtaactgaaaaaccaaatcttgtcatgcactggaatggtgagacaatcgttgacttggag
cgtcgtttccttgacaccaatggtgtgcgcgtggttgtcgatgccaaagttgtggacaag
gatgtcaaactcccagaagagcgtcaaacatctgctgaaacactggaatcagataccctt
acggttctatctgacctcaaccatgcaagtcaaaaaggattacagactatctttgactgc
tctgttggacgctcaacggttaatcacccacttggtggtcgttaccaactcacaccaact
gaggcatctgtgcagaaattgccagttcaacacggtgtgactcatactgcgtcggtcatt
gctcaaggtttcaacccatatgtagctgaatggtctccataccacggtgctgcttatgcg
gttatcgaagcaactgctcgtttggtggctgctggtgccaactggtctaaggctcgtttc
tcttaccaagaatatttcgagcggatggacaagcaagcagagcgttttggtcagccagta
gccgcccttctaggctctattgaagcacaaattcagcttggcttgccatctatcggtggt
aaggactccatgtctggtacctttgaagaattgaccgttccgccaaccttggttgccttt
ggggtgacgacggcagatagccgtaaggtgctctctccagaatttaaagctgttggggaa
aatatctactacatcccaggtcaagccctctctgcagagattgattttgacttgattaag
aaaaattttgctcagtttgaagcaagccaagctgaccataaagtgacatctgcatcagct
gtcaaatacggtggtgtagttgaaagtttggctcttgctacctttggaaactatattggt
gcagaggtgaccttgcctgaacttaaaacagctttgacagctcaattaggcggctttgtc
ttcacatctcctgaagaaattgctggagtagagaagattggacaaacgaaagcagacttt
acactgactgtcaacggtgtgaagctagatggacacaagcttgacagtgcatttcaaggg
acattggaagaagtttacccaacagaatttacccaagcgaaagaactagaagaagtacca
gctgtggtatcagatgttgtgattaaagccaaagaaaaggttgaaaaacctgtggtttac
atcccagtctttccaggaaccaactcagaatatgattcagctaaggccttcgaaaaagaa
ggtgcagaggtcaatttggtgccattcgtgaccttgaatgaagaagctattgtcaagtca
gttgaaactatggttgacaatatcgacaagactaatattctcttctttgccggtggattc
tcggctgcggatgaaccagatggttcagctaagtttatcgtcaatatcctgcttaatgaa
aaagtgcgtgtggctattgatagctttatcgcccgtggtggcttgattatcggtatttgt
aatggattccaagccttagtcaaatcgggtctcctaccatacggaaactttgaagatgct
aacagtactagtccaaccctcttctacaatgatgccaaccaacacgtggccaagatggtg
gaaactcgtattgccaataccaactcaccatggttggctggtgtgcaagtgggcgatatc
cacgctattcctgtttcgcacggtgaagggaagtttgtcgtgacggctgaggaatttgca
gagctccgtgacaatggacaaattttcagccaatacgttgactttaacggtaaaccaagt
atggattctaagtacaatccgaatggttctgtccatgccatcgaaggaattaccagcaag
aatggtcaaatcatcggtaagatgggccactcagaacgttatgaggatggtcttttccaa
aatatcccaggcaataaagaccaacacctgttcgcatcagcggttaaacatttcactgga
aaataa
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