Streptococcus pneumoniae TCH8431/19A (serotype 19A): HMPREF0837_10510
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Entry
HMPREF0837_10510 CDS
T01259
Symbol
folC
Name
(GenBank) bifunctional protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
snc
Streptococcus pneumoniae TCH8431/19A (serotype 19A)
Pathway
snc00790
Folate biosynthesis
snc01100
Metabolic pathways
snc01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
snc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMPREF0837_10510 (folC)
Enzymes [BR:
snc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMPREF0837_10510 (folC)
6.3.2.17 tetrahydrofolate synthase
HMPREF0837_10510 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ADI68738
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Position
459568..460818
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AA seq
416 aa
AA seq
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MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTGTNGKGSTIAFMRELFM
GHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKEMEKTLLQTPAQLSFFELL
TLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVITSIGLDHQETLGDSLEAIAEQ
KAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQAGQDFSVLNGDFSSSLLNLSQLN
IGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVRKALEQTHWAGRLERIRPQIYLDGA
HNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKDYQGMLGYLTENLPQVELKMTGFDYQG
SLDETDVTGYHVIPSYREFISSFEERADAQDLLFVTGSLYFISEVRGYLLDREQIN
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atgtttgaagtagaagaatggctccatagtcggattggtttgaattttcgatcaggtttg
ggccgaatgcagcaagcggtggatttgttaggaaatcctgagcagtcttaccctattatc
cacgtaacagggactaatgggaaaggatctaccattgcttttatgagggaattatttatg
gggcatggcaaaaaagttgcgacctttacctcccctcatatcgtctctatcaatgaccga
atctgcattaatgggcaacctatagcagacgcagactttatccgtttgactgatcaggtc
aaggagatggagaaaacgcttctgcaaactcctgcccagttgtccttttttgaattgctg
accttggttgcttttctttattttagggagcaagaggtggatttggttttattagaagtg
ggaattggtggcttacttgacacgaccaatgtggtaactggagagcttgctgtcatcacc
tccattgggcttgaccatcaagaaaccttgggtgatagtctagaagcaattgcagagcag
aaagctggtattttcaaggctggtaaaaaggcagtgattgcgaaattgcctccagaagct
agacttgtctgtcagaaaaaagccgaatctttagctgttgacctttatcaggcaggtcaa
gatttttcagtgctgaatggtgatttttcaagctctttactaaatctttcacagctgaac
ataggcttagaaggagcctatcagcaggagaatgcggccttggcgttgcaaacttttctt
ctttttatgggagaaagaaaggaagctattgatgaacaggctgtaagaaaggccttggaa
cagacccattgggctggtcgcttggagcgtattcgcccacagatttacttggatggtgct
cataacctccctgccttgactcgcttggttgagtttatcaaagaaaaagagcaggaaggc
tatcgacctcaaatcctctttggatccttgaaacgtaaggattatcaagggatgttgggt
tatctgactgaaaatttacctcaagtggaactcaaaatgaccggctttgactatcaaggg
tctttggacgagacagatgtaacaggttaccatgtaattccctcttaccgagaatttatc
agcagtttcgaagaaagggcagacgctcaagacttgctgttcgttacagggtctctctat
tttatctcagaagtacggggctacctgctggaccgtgagcagataaattga
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