Streptococcus pneumoniae TCH8431/19A (serotype 19A): HMPREF0837_10606
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Entry
HMPREF0837_10606 CDS
T01259
Symbol
folC
Name
(GenBank) bifunctional protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
snc
Streptococcus pneumoniae TCH8431/19A (serotype 19A)
Pathway
snc00790
Folate biosynthesis
snc01100
Metabolic pathways
snc01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
snc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMPREF0837_10606 (folC)
Enzymes [BR:
snc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMPREF0837_10606 (folC)
6.3.2.17 tetrahydrofolate synthase
HMPREF0837_10606 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ADI68834
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Position
543924..545246
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHIGGTNGKGSTIAFLKNM
LEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADYQSLLEGESATNLQGTTEF
EIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVTLLGDTLEAI
AEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPRLAYGADYHVSHQESVVTGEVFD
YTSAIRQGRFQTGLLGLHQIENAGMAIALLDTFCQEVGRKLPANILIAQALEETRWPGRL
EVVSRNPLMILDGAHNPHAIKALLATLQERFADYSKEILFTCIKTKALEDMLDLLGAMPD
TELTLTHFDDSRATDESVLEEAAKSRNLSYQGWQDFLEQKLTDKKEEKKTVRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaacaatcagtggattgctaactaccggacggaccaaccgcatttt
ggcttggaacgaatggtggaactgttagccttgcgtggcaatccccatctcaaactcaag
gtcatccatatcggagggaccaatggcaaggggtctaccattgcttttttgaaaaatatg
ctagaaaagctagggctgagagttggtgttttcagttcgccctatctcattcattacaca
gaccagattagcatcaatggggaatctatcccagaggctagactagaagccctcatggca
gactatcagtctttgctggaaggggaatcggctaccaatttgcaggggacaactgagttt
gaaataattacagctatagcctatgattactttgcctcagagcaagtagatgtggctatc
atggaagtgggtatgggtggactcttggatagtaccaatgtctgtcagcctattttgaca
ggaattacgactattggattggaccatgtaaccctacttggtgacaccttggaagccata
gcagagcagaaagctggtattatcaaacaaggtattcccttggtgacaggtcgtatcgct
ccagaagctttggctgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacggggcagattatcatgtcagtcaccaagagagtgtggtaacgggtgaagtctttgac
tatacaagtgctatcagacaaggtcgcttccaaactggcctgcttggtttgcaccagata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagttggtcgaaag
ttaccagctaatatcttgattgctcaagctctggaagaaacaagatggccggggcgtctg
gaggtcgtgtcaaggaaccccttgatgatcttggacggggcccacaatccccatgctatc
aaggctttattggcaaccttgcaagaacgctttgcggattatagtaaggaaatcctcttt
acttgtatcaaaaccaaggccttggaggatatgttggacttgctgggggccatgccagat
accgagcttactctgacacattttgacgatagtcgggcgactgatgaaagcgtgctggaa
gaggcagctaagtctagaaatctcagctaccaaggttggcaggattttctagagcagaaa
ttgacagataaaaaagaagagaaaaaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagagcctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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