Streptococcus pneumoniae ATCC 700669 (serotype 23F ST81 lineage): SPN23F16710
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Entry
SPN23F16710 CDS
T00843
Symbol
murF
Name
(GenBank) putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sne
Streptococcus pneumoniae ATCC 700669 (serotype 23F ST81 lineage)
Pathway
sne00300
Lysine biosynthesis
sne00550
Peptidoglycan biosynthesis
sne01100
Metabolic pathways
sne01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sne00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPN23F16710 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPN23F16710 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPN23F16710 (murF)
Enzymes [BR:
sne01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPN23F16710 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HBS1_N
Motif
Other DBs
NCBI-ProteinID:
CAR69443
LinkDB
All DBs
Position
complement(1609146..1610519)
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AA seq
457 aa
AA seq
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MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFE
NGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAH
LLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAI
VTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGA
ELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQ
HLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKEL
GDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFED
LVKQVKESLGAYDQILLKGSNSMNLAKLVESLENECK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacaatccatgaaattgcccaagttgttggagccaaaaatgatatcagtatc
tttgaggacactcagttagaaaaagctgagtttgatagtcgtttgattggaactggagat
ttatttgtgccacttaaaggtgcgcgtgatggccatgactttattgaaacagcctttgaa
aatggtgcagcagtaaccttgtctgagaaagaggtctcaaatcatccttacattttagta
gatgatgttttgacagcctttcaatccctagcatcctactatcttgaaaaaacgactgtt
gatgtctttgctgttacaggttcaaatggcaagacaacgactaaggatatgttggcgcat
ttactgtcaacaagatacaagacctacaaaacacaaggcaattacaataatgagattggc
cttccttacacagttcttcatatgcctgaaggaacagaaaagttggttttggagatggga
caggatcacttgggagatattcatctcttgtctgaattggctcgtccaaaaacagccatc
gtgaccttggttggagaagctcatttggcctttttcaaagatcgttctgagattgctaaa
ggaaaaatgcaaattgcagacggaatggcttcaggttccttgcttttagcgccggctgac
cctatcgtagaggactatttgccaattgataaaaaggtggttcgttttggtcaaggagca
gagctggaaattactgacttggttgagcgtaaggacagtctgacctttaaggctaatttc
ttggaacaagcccttgatttgccagtaactggcaagtacaatgcgacaaatgctatgatt
gcatcctatgttgccttgcaagaaggagtttcagaggagcaaattcgtttggcattccaa
catcttgaattgacgcgtaaccgtaccgagtggaagaaagcagccaatggagcagatatc
ctgtcagatgtttacaatgccaatccaactgctatgaaactgattttagagactttctct
gccattccagccaatgaaggtggcaagaaaattgcagtgttggcggatatgaaggagctt
ggtgaccagtctgttcaacttcataatcagatgattttgagcctctccccagatgtgctt
gatatcgttattttctatggagaagatattgctcagttggctcaattggccagtcaaatg
tttccaatcggccacgtttactacttcaagaaaacagaagaccaggatcaatttgaagac
ctagtcaagcaggttaaggaaagccttggagcctatgaccaaatcttgctaaaaggttct
aactctatgaatctagccaaattggtagaaagtttagaaaatgaatgcaagtga
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