KEGG   Serratia nematodiphila: NLX84_09240
Entry
NLX84_09240       CDS       T08619                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
snem  Serratia nematodiphila
Pathway
snem00290  Valine, leucine and isoleucine biosynthesis
snem00620  Pyruvate metabolism
snem01100  Metabolic pathways
snem01110  Biosynthesis of secondary metabolites
snem01210  2-Oxocarboxylic acid metabolism
snem01230  Biosynthesis of amino acids
Module
snem_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:snem00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    NLX84_09240 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NLX84_09240 (leuA)
Enzymes [BR:snem01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     NLX84_09240 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: UTO03205
LinkDB
Position
1959235..1960923
AA seq 562 aa
MLIDPSSKYRPFPPVALPDRQWPARTLRQAPRWCSSDLRDGNQALAEPMDNARKREFYQL
LLQCGFKEIEVAFPSASQTDFDFVRTLIDERLIPDDVTIQVLTQSRDDLIDRTFEALQGA
PRAIVHLYNATAPMFRDIVFRQDKAATVALAVNGARRIRRQCEAQPDTAWCFEYSPETFC
FTELEFALEICEAVAEVWQPGPQRPMIINLPATVEVSTPNVYADQIEWFCRHFSRRADVA
ISVHPHNDRGTGVACAELALLAGADRVEGCLFGNGERTGNVDLVTLALNLYTQGVAPGLD
FSRLKQVVEVVEQCNQLPVHPRHPYAGELVCTAFSGSHQDAIKKGFAAQRQRQDGRWQVP
YLPLDPADVGCSYEAVIRVNSQSGKSGAAWLLEQNHGLALPRGLQIDFSQVVQRATDGSG
KEMSGAQLWRLFRDTYGLVEQPRLQLLSYQTESHGAEAYSFNARVACEGEPLRLQGAGNG
LLSSAVDALRQRFGLPLAIEDYHEHTLGHQSDSRAVAYIRCTLPQGEATYGVGIDVDSAS
ASLQALFNVAGRYLAPTSAQSG
NT seq 1689 nt   +upstreamnt  +downstreamnt
atgttaatcgacccttcaagcaaataccgaccgttcccgccggtggcgttgccggaccgc
caatggcctgcgcgtacgctgcggcaggcgccgcgctggtgctccagcgatctgcgcgac
ggcaaccaggcgctggcggagccgatggataacgcgcgcaagcgcgaattctatcaattg
ttgttgcagtgtggtttcaaagagatcgaggtggcgttcccttcggcgtcgcaaacggat
ttcgactttgtacgcacgctgatcgacgagcggctgatcccggacgacgtcacgatccag
gtgctgacgcagtcgcgcgacgatctgatcgatcgcaccttcgaggcgctgcagggggcg
ccgcgggctatcgtgcatctgtataacgccacggcgccgatgtttcgcgacatcgtgttc
cgccaggataaggcggcgaccgtggcgctggcggtgaacggcgcgcggcgcattcgccgg
cagtgcgaggcgcagcccgataccgcctggtgcttcgaatattcgccggaaaccttctgt
tttactgagttagagtttgcgctggagatctgcgaagcggtggcggaggtttggcagccg
gggccgcagcggccgatgatcatcaacctgccggcgacggtggaagtgagcacgcccaac
gtgtatgccgatcagatcgaatggttctgccgtcacttcagccgtcgcgccgatgtggcg
atcagcgtgcatccgcataacgatcgcggcaccggcgtggcctgcgcggagctggccttg
ctggccggcgccgatcgggtcgaaggctgcctgttcggcaacggagagcgcaccggcaac
gtcgatctggtcacgctggcgttgaatctctatacccagggcgtggcgccgggtctcgac
ttcagccgcctgaagcaggtggtggaggtggtggaacagtgcaatcagctgccggtgcat
cctcgccatccttatgccggcgagttggtgtgtaccgccttctccggttcgcatcaggat
gcgatcaagaaaggtttcgccgcacagcggcagcggcaagatggccgctggcaggtgcca
tacctgccgctcgatcccgccgatgtcggttgcagctatgaggcggtgatccgggtcaac
agccagtccggcaaaagcggcgccgcctggctgttggagcagaatcatgggctggcgttg
ccgcgcggtttgcagattgatttcagccaggtggtgcagcgcgcgaccgacggcagcggc
aaagaaatgagcggcgcgcagctgtggcgcttattccgcgatacttacgggctggtggag
cagccgcgtttgcagctgttaagctaccagacggaaagccatggcgcagaggcatacagc
ttcaacgcgcgagttgcctgcgagggagagccgctgcgcctgcagggggccggcaacggt
ctgctgtccagcgcggtggatgcgctgcgtcagcgcttcggcttgccgctggcgatcgag
gattaccacgagcataccttggggcatcagagcgatagccgagcggtggcttatattcgc
tgtacgctgccgcaaggtgaggcgacttatggcgttggcatcgacgtcgactccgccagc
gcctcgctgcaggcgctgttcaacgtcgccgggcgctatctggcgccaacgtcggcgcag
tccggctga

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