Salvelinus namaycush (lake trout): 120023630 Help Entry 120023630         CDS       T07522                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism snh  Salvelinus namaycush (lake trout) Pathway snh04020   Calcium signaling pathway snh04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:snh00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     120023630    04020 Calcium signaling pathway     120023630  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:snh04040]     120023630 Ion channels [BR:snh04040]  Voltage-gated cation channels   Ryanodine receptor    120023630 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Motif Other DBs NCBI-GeneID:  120023630 NCBI-ProteinID:  XP_038823603 UniProt:  A0A8U0PEC8 LinkDB All DBs Position Sna28:complement(27363274..27554135) Genome browser AA seq 4877 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIHKENRKFCLTAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLAKTGQNSEGAAQGGGHRTLLYGHAILLRHSFSAMYLTC LKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSISNGNIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVLRLFHGHDEVLTIPGSDQS DEQQRIVNYETGNAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLALTEERG VVLQDREKSDTSSTAFCFRASKEKLESSPKRDIEGMGMAEIKYGDSICFVMHVATGLWLS YQAPDVKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTRLFSHFIRDL DCLGGKNRASVALPIEEVLQTLNDLITYFQVPNAELEHEEKQIMLRSLKNRQNLFKQEGM LTLVSCCIDRLNVYNSAAHFGECAGEEAGASWKDILNLLYELLAALIRGNRNNCTQFSNN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIYLGMSEGSAQYKKWY YELMIDQVDHFLTSDPSHLRVGWATNKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRISRAVASINQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNIDGLFFPVVSF SAGVKVRFLMGGRHGDFKFLPPLGYAPCYEALLPKEKMKVEPVKEYKRDMEGVRDLLGTT QFMSQASFIPTPVETSQIVMLPYLEKVRDRLAENIHELWAMNKIELGWSYGKIRDDNKRQ HPCLVDFSRLPETEKNYNLQMSTETLKTLLALGCHVVQVNANAEENLKKIKLPKNYMMSN GYKPTPLELSDMKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDVKSKRNPRLVP YSLLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEGAGHVVDRLSIDKIRFFRVERTYA VMTGKWYFEFDVVTGGDMRVGWARPGCRPDVELGTDELAFVFDGYKGQRLNMGSRFFGRC WHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQVGRM NLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKNHNHIMVTRIDG TIDSPPCLKVSHRTFGTQNSNGDMVYCRLSMPVEFHSFFKTSPVMDMNGFRCHVVKLTCH HVVLQYHYSVRVFAGQDPSCVWVGWVTPDYHYYSNHFNLSKNRTVTVTLGDQRGRVHESV RRSNCYMVWGGDVTSSGHSSSRSNVDLEIGCLIDLATGLVTFTGNSKELATSYQVEPNTK LFPAVFVRPTSPNLFQFELSKIKNAMPLSAAIFKSEHKNPVPQCPPRLDVQTINSVLWSR MPNTFLKVETARVSERHGWVVQCLEPLQMLAVHIPEENRCVDIMELSEQEDLRKFHYHTL KLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNILISIHLETAKEAR LMMNNEFIIPITAETRSIRLFSDASRHHSPPGVGLSTSLKPRLNFYPPCFISTKREQHLY SPQIPLDALKEKAITMLTDAVQGGGHHIRDPVGGSVEYQFVPILRLIGTLLTMGVLGSHD VHKILLLIDPNVFVEHSEEAVAVVEATEKEGLTGTEEKAVEAGEEEAAKDAKLPMKGLLE KRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQYNQKFRYNELMLALNMSA AVTAKKTKEFRSPPQEQINMLLNFSTGEDCPCPEDIQEELYAFHNELRLHCGIPMEEEED DQDTSIKGRLLALVYKIKDQPLKTEEEPTEQEQQAPSNLKELISQTMVSWAQECHVQDPE LVRVMFSLLRRQYDSIGELLRAMRKSYTISAASIQDTINLLASLGQIRSLLSVRMGKEEE KLMIDGLGDIMNNKIFYQHPNLMRVLGMHETVMEVMVNVLGGGKSQIAFPKMVASCCRFL CYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAASSVMDNNGLALALEEP DLDKVVTYLAGCGLQSCPMLLDKGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENSSVV VKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISENPALDLPSSAQGVSSDMSAEDDEEE EVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTEDLVGIISIA LKMPVIHKDGTVTEPDMAASFCPDHKAPMVLFLDRVYGIEDQSFLLHLLEVGFLPDLRAS ASLDTEVLSTTETALAMNRYIGSAMLPLLTRCAPHFAGTEHYATLIDSTLHTIYRLSKGR SLTKAQRDAIEECLLAVCRYLRPSMLQQLLRRLVFDVPLLTEYCKMPLRLLTNHYEQSWK YYCLPSGWGSYGMASDEELLLTKKIFWGVLDSLSQRKYDADLFKMAMPCLSAISGALPPD YIDSTISTTLEKPVSVDAQGNFDPKPISTANISLPEKLENVANKYAEHSHDKWSAEKVML GWKYGDCIDEKAKTHPQLRTYKGLTEKEKEIHRLPVRETLKSMLAMGWNIDRTKDGETMS LRESEKMRKISQSSSQGNGFNPTPIDTSNVVLSRELQGMMEVVAENYHNIWAKKKKNDLG IRGGATHPLLVPYDTLTAKEKARDKEKAQDLFRFLQINGYAITRCLKDMEQDSSSMEKRF AYKFLKKLLKYVNSAQEFIAHLEAMATSGKTDKSPHEQEIKFFAKVLLPLIDQYFKNHCL YFLSSPSKNLSSSGYASNKEKEMVTSLFCILAALVRHRISLFGSDSTTMVSCLHILAHTL DTRTVMKSGSELVKAGLRTFFENAAEDLEKTFENLKLGKFTHSRSQMKGVSQNINYTTVA LLPILTALFEHITQHHFGVDLLLDDVQVSCYRILTSLYALGTGKNIYVERQLPALGECLA TLAGAMPVAFLEPLLNKHNPCSVFNTKTARERAILGMPDVVEEMCPEMPRLDVLMKDIND MSESGARYTEMPHVIEVVLPMLCNYLSYWWEKGPENQASPHSGGSVFSTTVTSEHLSLIL GNILKILNSNLGIDEASWMKRIAVYAQPIISKARAVLLKSHFLPTLEKLKKKTVKVVTEE ELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIHYVDNNRSRWLKEPDADSNELFR MVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKMSKSGGQDQERKHKRKRGE FYSIQTSLIVAALKKMLPMGLNMCTPGDQELISLAKTRYLLKDTDDEVKDHVRQNLHLQE KSDDPAVRWQLNLYKDVMVKNEGPPDPERTVFRVQSISAAVFHLEQVEQPLRSKKCVWQK LLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLGYQRIWIETETYSFEEKLVQDLAKTQL KVEEEEEEEAEIQPDPLHQLILHFSRNALTERSSLEEDPLYIAYADMMAKSCAEDEEEED EEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMVLQMISASKGTLGPMVTFTLKLGISIL NGGNILVQQKMLDYLKEKGDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSI NVSERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKDIMDEAGQRNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMMLSLLEGNVVNGTIGKQMV DTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPESKGVISKKEFQKSMENQKQYSQ SEIEFLLSCAEADENDMFNYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPHDARLATFLD LAESVINYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEG GESEKMELFVNFCEDTIFEMQLASQISEPDAVERLEEDDEDSQSVTEEPEEEEEESMMES HSAFTNSCVSMRKNLFSFRQLLTFKSMRRQYRRFRKMSVREMVQGFFSFFWMIITGLFRF LYNLVWGFFHILWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLETEKMEASEA SSVAEMGHMGQGDKAEADLMAELLNIQTKSQGGKHAPEPGLGDMGEVVGVDAPSLASAVK QKKAKDYMCFLKEAATKEPTNGDHKAEPEKSDPEDGEKKDQDKVKEEAPPEPSPEEKKAP KKRPGLKKESPEEFMANFFSSLDIYQTKMLNYLARNFYNLRFLALFVAFAINFILLFYKV TGDDGDDDDPDPWNGGGATDEEEDEGGMEYFVLQESTGYMAPTLRFLAILHTVISFLCVV GYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKF VKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETVVKEASLVSWLSSIDTKYQCWKM GVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLT VGLLAVVVYLYTVVAFNFFRKFYNKSEDDNQPDMKCDDMMTCYLFHMYVGVRAGGGIGDE IEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFI CGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERLWD FFPAGDCFRKQYEDQLG NT seq 14634 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggtgaaggggaagatgaaattcagttcttgagaactgatgatgaagtg gtgctccagtgtgtcgcctgcatccacaaggagaatcgcaagttctgtctgacagcagag gggctcggcaatcgactgtgctacctggaacccacatcagaggcaaagtatgtccctcca gacctatgcatctgcaactttgtgctggagcagtctctctctgtgcgggccctgcaggag atgcttgctaagactggtcagaacagtgaaggggcggctcagggcggtggacacagaaca cttctgtatggacacgccatcctcctgaggcactcctttagcgctatgtatctgacctgt ttgaagacgtcaaggtcacagacagataagctgtcctttgatgtggggctgcaggaggac tcaacaggtgaagcctgttggtggaccatccatcctgcttccaaacagaggtcagagggc gagaaggtacgcatcggagatgacctcatccttgtcagcgtgtcatcagaacgatacctt cacctgtccatctccaatggcaacatccaggtggacgcgtccttcatgcagactctgtgg aacgtccaccccacctgctccggcagcaacgtggaggagggttacctgctgggtggccat gtgttgcgtctgttccatggtcatgatgaggttttgaccatcccagggtctgaccagagt gatgaacaacagaggatagtgaactatgagacggggaatgcaggagccaaggccaggtct ctgtggaggctggagcctctcagaatcagctggagcgggagtcacattcgctggggtcag cccttccgtctccgccacctcaccactgggcactacctggccctgacggaggagaggggg gtggtgctgcaggaccgggagaagtctgacacttcctccaccgccttctgcttcagagcc tccaaggaaaagctggagtcgagccctaagcgggacatcgagggcatggggatggcagag attaagtatggggactcaatctgcttcgtcatgcatgtggctacaggactctggctgtcc taccaggcgcctgatgtaaaatcatctcgcctgggccctctcaagagacgggcctgcctc cactctgagggtcatatggatgatgggctgaccttgcagcggtgtcagcacgaagagtcc cgtgctgctcgcatcatccgtaacaccacccgcctcttcagtcacttcatcagagacctg gactgtctggggggaaagaaccgtgcgtcagtagccctgcccatcgaggaggtcctccag accctcaatgacctcatcacctacttccaggtgcctaatgctgagctggagcacgaggag aaacagatcatgctgcgctctctcaagaaccgacagaacctcttcaaacaggaaggcatg ctgactctggtgtcctgctgcatcgaccgtctcaacgtgtacaacagtgcagcccacttt ggggagtgtgccggggaagaggctggggcttcctggaaggacatcctcaacctgctctat gagctgctagcggcgctgatccgaggcaacaggaacaactgcacccagttctccaacaac ctggactggctggtcagcaagctggagagactggagtcctcctcaggcatactggaggtt ctccactgcattctaattgagagcccggaggctctaaatatcatccagagaggacatatc aagtccatcatctccctgctctacaaacatggacgcaaccacaagattttggatgttctc tgttccctgtgtgtgtgtaatggggtggcagtacgagccaatcagaacctcatctgcgat cacctgctccccaaaagagatctgcttctacagacccgattggtcaatgatgttcaaagc atgaggcccaacatttacctgggaatgagtgaaggctcggcccagtataagaagtggtac tacgagctgatgattgatcaggtggaccacttcttgaccagcgatccctctcacctgcgt gtgggctgggccaccaacaagggttacgccccttacccaggtggaggggagggttggggg ggcaacggggtgggggatgacctctactcttatggctttgacggacttcatctctggtca ggtcgtatctcccgggcggtggcttctattaaccaacacatcctgacctctgaggatgtg gtgagctgttgtctggacctgggagcccccagcatctcctttaggatcaatggacagccc gtacagggcatgttcgagaacttcaacatcgatggactcttcttccctgttgtcagcttt tccgctggggtcaaggtgcgtttcctgatgggcggtcgtcatggcgacttcaagttcctg cctccgttgggctatgctccgtgttacgaggccctgctccccaaggagaagatgaaggtg gagccggtgaaggagtacaaaagggacatggagggggtacgagacctgctggggaccaca cagttcatgtctcaggcctccttcatacccacccctgtggagaccagccagattgtcatg ctgccatacctggagaaggtccgggacagactggctgagaatatccacgagctgtgggcc atgaacaagatagaactgggctggtcttatgggaagataagggacgataataagcggcag cacccctgccttgtggatttttccagactgcctgaaacggaaaagaattacaacctgcag atgtcaacggaaaccttgaagactctgctggcattaggatgccatgttgtccaggtcaac gccaacgctgaagagaacctgaagaagatcaaactcccaaagaactacatgatgtcgaat ggttacaagcccacgccactggagctgtctgacatgaagctgaccccaggccaggaactt ctggtggataaactggcggagaacgcccacaacgtgtgggccaaggacaggatcaaacaa ggatggacctatggcattcagcaggatgtgaagagcaagcggaaccctcgcctggtgcca tattctttattagacgagcgtactaagaagtccaacagggacagcctccgtgaggccatc cgcactctgattggatatggatacaatatcgaacctccagatcaggagggcgcaggccat gtggtggacagactgagcatcgacaagatccgtttcttccgtgtggagaggacgtacgcg gtgatgacggggaagtggtactttgagtttgatgtggtgacagggggagacatgcgtgtg ggctgggccagacctggatgtaggcctgatgtagagctgggcactgatgagctggccttt gtcttcgacggatacaagggtcaacgtctgaacatgggcagtcgtttctttgggcggtgt tggcacgcgggggacgtggtgggctgtatgatcaacatggaggacaagtctatgatcttc accctcaacggagagatcctcatcaccaacaagggctctgagctctgctttgccgacttc gagacagaggacggttttatcccagtgtgtagtctgggcctgtcccaggtgggtcgtatg aacctggggaaggacgccagtacctttaagtactacaccatgtgtggtctccaggagggc ttcgaacccttcgccgtcaacatgaaccgtgaggtcaccatgtggttcagcaaacgcctc cccacctttgtcaatgtgccaaagaaccacaaccacataatggtgaccagaatagatggc accatcgacagccctccatgtctgaaggtgagccacaggacgtttgggacccagaacagt aatggtgacatggtgtactgtcgactgagcatgcctgtggagttccactccttcttcaag accagccctgtcatggacatgaacggattcaggtgccatgtagtcaagctaacctgccac catgttgtcttgcagtaccactactctgtcagggtgtttgctggtcaggatccatcctgt gtgtgggtgggctgggtcacccccgactaccattactatagcaaccacttcaacctcagt aagaaccggacggtgacggttaccctgggagaccagcgtgggcgggtccatgagagtgtg aggaggagtaactgctacatggtgtggggtggggacgtcaccagctcaggtcactcatcc agtcgcagtaatgtggacctggagataggctgtctcattgacctggccactggcctggtg accttcactggcaacagcaaggagctggccacctcctaccaggtggaaccaaacacaaag ctgtttcctgctgtgtttgtgcgaccgaccagccccaacctcttccagtttgagctgtcc aagataaagaatgccatgcccctgtcagctgccatctttaagagtgagcataagaaccca gtaccccagtgccctccgaggctggacgtccagaccatcaactcagtgctgtggagtcgc atgcccaacaccttcctaaaggtggagacggccagggtcagtgagagacacggctgggtg gtgcagtgtctggagcccctgcagatgctggctgtgcacatacctgaggagaacaggtgt gttgacatcatggagctgtctgagcaggaggacctgaggaagttccactaccacaccctg aagctgtactgtgccctgtgtgccctgggaaacacccgcgtggcacacgccctctgcagc cacctggaccaatcccagctgctctacaccatcgacaaccagtacctgtcgggcatgctg cgcgagggcttctacaacatcctgatcagcattcacctggagacggccaaggaggcccgc ctcatgatgaacaacgagtttattatccccatcaccgccgagacgcgaagcatccgcctg ttctccgatgcctccaggcaccactctcctcccggggtgggcctcagtacctccctgaag ccccggctcaacttctaccccccctgcttcatcagcaccaagagggagcagcacctgtac agcccccagatccccctggatgccctgaaggagaaggccatcaccatgctgaccgatgcc gtgcaaggcggtgggcatcacatcagggaccctgtagggggcagcgtggagtaccagttt gtgcccatcctgaggctgattggtacactgctcaccatgggcgtgctgggcagtcacgat gttcataagatcctgctcctcatcgaccccaacgtgtttgtggagcatagcgaggaggcc gtcgccgtggtggaggccacagagaaggaggggctgacgggcaccgaggagaaggcggtg gaggccggggaggaggaggcggctaaagacgccaagctgccaatgaaaggtctgctggag aagaggctgcctgagccagtgaaacgacagatgtgtgagctgctgcactacttctgtgac tgtgagctgaagcatcgcatcgaggccattgtgtccttctcagacagctttgtctccaag ctgcagtacaaccagaagttcaggtacaacgagctgatgctggccctcaacatgtctgct gccgtcaccgccaagaagaccaaggagttccgctcccctccccaagaacagattaacatg ctgttgaacttcagtacgggggaggactgcccatgtccagaggacattcaggaggagctc tatgccttccacaacgagctgcggctgcactgtggaatccctatggaggaagaggaagat gaccaggacacgtctattaaaggtcgtctgctggccctggtctacaaaatcaaagatcaa cctctgaagactgaagaggagcccacggagcaggaacagcaagccccctccaaccttaaa gagctgattagccagaccatggtgagctgggctcaggagtgccatgtccaggaccccgag ctggtcagagtgatgttcagcctgctgaggagacagtacgacagcattggagaactgctc cgggccatgaggaagagctacactatcagtgctgcctctatacaggacaccatcaacctg ctggcctctctgggtcagatcagatcactgctgtccgtacgcatgggcaaggaggaggag aaactcatgatcgacggtctgggtgacatcatgaacaacaagatattctaccagcacccc aacctgatgcgtgtgctgggcatgcatgagacggtgatggaggtgatggtcaacgtgctg ggaggagggaagtcccagatagcgttccccaagatggtggccagctgctgtcgcttcctg tgttacttctgcaggatcagtcgtcagaaccagaaggccatgtttgaccacctcagctac ctcttggaaaacagcagcgtgggcctggcgtccccggccatgaggggctctactcctcta gacgtggctgcctcctctgtgatggacaacaacggcctggccttggccctggaggaaccc gacctggataaggtggtgacgtacctagcaggctgtgggctccagagctgtcccatgctg ctggacaaaggttaccctgacatcggttggaaccccatagagggcgagcgctacctctcc ttcctgcgctttgctgtctttgttaatggtgagagtgtggaggagaactccagtgtggtg gtgaagctactgatcaggcgtccagagtgttttggtccggccctgagaggagaggggggt aacgggctgctagcagccatgaaggaggccatcaagatctctgagaaccctgctctggac ctgccctcctctgcccagggggtcagctctgacatgtctgctgaggatgatgaggaggaa gaggtggttcacatggggaatgccatcatgtccttctactctgccctcatcgacctattg ggacgctgtgccccagagatgcacttgattaacaaggggaaaggggaggccctgcgtatc cgtgccatcctgcgctccctagtgcccactgaagacctggtgggcatcatcagcatagcc ctcaagatgcctgtcattcacaaagacggcactgtgaccgagcctgatatggcggccagt ttctgcccggaccacaaggcccccatggtgctattcctggaccgggtctatggtatcgag gaccaaagcttcctacttcacctgctggaagtgggcttcctgccagacctgcgagcctct gcttctctggacacggaggtactcagcaccacagagacagctctggccatgaacaggtac attggctctgccatgcttcccctgctcacccgctgtgccccccacttcgctggcacagag cactacgccacgctaatcgactccacgctacacaccatctacaggctgtccaagggccgc tcgctcaccaaggcccagagagatgctatcgaggagtgtctgctggctgtctgcaggtac ctccgcccctccatgctgcagcagctcctgcgccgcctggtctttgacgtgcccttgctg acagagtactgcaagatgcctctcaggctcttgaccaaccactacgagcagagctggaag tactactgtctgccgtcaggctggggcagctacggcatggcctcagacgaggaactgctc ctcacaaagaagatcttctggggtgtcttggattcgctctcacagaggaagtacgatgca gatctctttaagatggccatgccctgtctgagtgccatatctggggccttaccgcctgac tacatagactccaccatcagcaccaccctggagaagcctgtgtctgtggatgctcagggc aacttcgaccccaaacccatcagcacagccaacatatctcttccagagaaactggaaaat gttgccaacaaatatgctgagcattcccatgacaaatggtcagccgagaaggtgatgttg ggatggaagtacggagactgtatagatgagaaggccaagactcaccctcagctcaggacc tacaaaggccttacagagaaggagaaggagatccacaggttgccggtgagggagactcta aagagcatgctggctatgggctggaacattgacaggaccaaggatggagagaccatgtcc ctacgggagagtgagaagatgcggaagatctcccagtcctcctctcagggtaacggtttc aacccaacaccaatagacaccagcaatgtggttctgtctagagagttacagggcatgatg gaggttgtggctgagaattatcacaacatctgggctaagaagaaaaagaatgaccttgga attagaggtggggcaactcaccctctgctagtgccctatgacaccctgactgccaaagag aaggcccgggacaaagagaaggcccaggacctgttccgcttcctacagatcaatggctat gctatcaccagatgtctgaaggatatggagcaggactcttcctccatggagaagaggttt gcctacaagttcctcaagaagctcctcaagtatgtgaactcagcccaggagttcattgcc caccttgaggccatggctaccagtggtaagacagacaagtcacctcatgagcaagaaatc aagtttttcgccaaagtcctcctccctctgatagaccagtacttcaagaaccactgtctc tacttcctgtcttctcccagtaagaacctgagcagcagcggctatgcatctaataaggag aaggagatggtcaccagcctgttctgtatactggcagctcttgtcagacacaggatttcc ctcttcgggagtgactccaccaccatggtgagctgtctccacatcctggcccacacactg gacaccaggacggtgatgaagtctggctcagagctggtgaaggcggggttaaggacgttc ttcgagaacgcagcggaggacctggagaagacctttgagaacctgaagttggggaagttc acccactcccgctcacagatgaagggcgtgtcccagaacattaactacaccacggtggca ctactgcccatcctcactgccctgtttgaacacatcacccagcaccactttggagtggac ctgctcttggatgatgtccaagtgtcatgctatcgtatcctgaccagcctgtatgcactc gggactggaaaaaacatctacgtggaaaggcagctgccggccctgggggagtgtctggcc accctggcaggcgccatgcctgtggccttcctggagcctctgctcaacaaacacaacccc tgctctgtgttcaacaccaagactgcccgcgaacgcgccatcctaggcatgccagacgtg gtggaggagatgtgtccggagatgcctcgtctagacgtcctgatgaaggacatcaacgac atgtctgagtctggggcgcgctacacagagatgccccacgtcatcgaggtggtgctgccc atgctgtgtaactacctgtcctactggtgggagaagggcccagagaaccaggcgtctccg cacagcgggggcagtgtcttctccaccaccgtcacctcagaacacctcagcctcatcctg ggaaacatcctgaagatcctcaacagcaacctgggcatcgacgaggcctcctggatgaag aggatcgcagtgtacgcccagcctatcatcagtaaggccagggctgttctgttgaagagt cacttcctgcctacgctggagaagctgaagaagaagacagtgaaggtggtgacggaggag gagctactgaaagctgacagtaagggagatacccaggaggctgagctcctcatcctggat gagttcgctgtgctctgcagagacctctacgccttctacccgatgctcatccattacgta gacaataacaggtccaggtggctgaaagaaccagacgctgactccaatgaactcttcaga atggtggctgagatcttcatcctctggtgcaaatcacataacttcaaaagggaagagcag aactttgtggttcagaatgaaatcaacaacctgtcattcctgactggtgatagcaagacg aagatgtcaaagtcagggggtcaggaccaggagaggaagcataagaggaagcgaggagag ttctactccatccagacatccctgatcgtggctgccctgaagaagatgctgcccatggga ctcaacatgtgcacccccggggaccaggagctcatctccctggccaagacacgttacctc ctgaaggacacagatgatgaagtgaaggaccatgtgcggcaaaatttgcaccttcaagaa aagtcagacgaccctgcagtgaggtggcagctgaacctttataaggatgtgatggtgaag aacgaggggcctccagaccctgagaggacagtgttcagagtccagagcatatcagctgca gtcttccatctggagcaggtggaacagccgttgaggtctaagaagtgtgtgtggcagaag ctgctgtccaagcagagaaagcgtgcggtggtggcctgcttccgcatggctcctctctac aatctgcccaggcatcgctctattaacctcttcctcctgggctatcagagaatatggata gaaacagagacgtactcttttgaagagaagctagtgcaggacctggcaaagacccaactg aaggtggaggaggaggaagaggaggaggcagagattcagccagaccctcttcatcagctc atcctgcatttcagtcgcaatgcgctcactgagcgaagttctttggaagaggatcctttg tatattgcgtatgcagacatgatggcaaagagttgtgcagaagatgaagaagaagaagat gaagaaggaaaagagaaaacgtttgaggaaaaagagatggagaaacagaagactctgtac cagcaggccaggctgcatgacagaggagctgctgagatggtgttacagatgatcagcgcc agcaaaggtacgcttgggcccatggtgacctttaccttgaagctgggcatctctatactc aacggaggcaacatactggttcagcagaaaatgcttgactatctgaaggaaaaaggagat gctggctttttcaagagtttgtcaggactcatgcagtcttgcagtgtcctggatttgaat gcattcgaaaggcaaaacaaagcggaaggtcttgggatggtgacggaggaaggatcaatc aacgtgagtgagcggggttccaaagtactgcaaaacgatgagttcactaaggatctcttt aggtttctgcaactgctctgtgagggacacaacaacgacttccaaaacttcctgcggact caaacaggaaacacgaccactgtaaatatcatcatcagcactgtggactacctgctccgt ctgcaggaatccatcagtgatttttactggtactactctgggaaagacatcatggatgag gctggccagcggaacttctccaaagccctggctgtggccaagcagattttcaactctctc actgagtacatacagggcccttgtattgggaaccagcagagtctggcacacagcaggcta tgggatgcagtggtgggattcctgcatgtgtttgccaatatgcagatgaagctgtcacag gattcaagtcagattgagttattgaaggagctgctggacctgcagaaggacatgatcgtg atgatgctctcccttctggaaggtaacgttgtcaacggaaccatcgggaaacagatggtg gacaccctggtggagtcctccagcaatgtggagatgatcctcaagttcttcgacatgttc ctcaaactcaaagacctgaccacctcggacaacttcaaggagtatgacccggagagcaag ggagtgatctccaagaaggagttccagaagtccatggagaaccagaagcagtactcccag tccgagatcgagttcttgctctcctgcgccgaggctgacgagaacgacatgttcaactac gaggagtttgtgaagcgctttcatgagccggccaaggacattggctttaacgtggcggtc ctgctcaccaacctgtcagaacacatgcctcacgacgcccgtctggccaccttcctggac ctggccgagagcgtgataaactacttcgagccctacctgggccgcatagagattatgggc ggagccaagcgcatcgagagggtctactttgagatcagcgagtctagtcgtacacagtgg gagaagccccaagtcaaagagtctaagagacagtttatctttgacgtggtgaatgagggt ggagagagcgagaagatggagctgtttgtcaacttctgtgaggacaccatatttgagatg cagctggcctcacagatctctgagcctgacgcagtggagcgtctcgaggaggacgacgag gacagccagagtgtgacggaggagccagaggaggaagaggaggagagcatgatggagtct cactccgccttcaccaactcctgcgtctccatgaggaagaacctgttcagcttccgccag ctgctgaccttcaaaagcatgaggcggcagtacaggaggttcaggaagatgagtgtgagg gagatggtccaaggcttcttctcattcttctggatgattatcacgggcctcttccgcttc ctttataacctggtgtggggcttcttccatatcctgtggtcctccatgtttggcgggggc ctggtggagggggccaagaacatgaaggtcacagacatcctggggaacatgcccgacccc acacagtttggtatccatggtgatgtgctggaaacagagaagatggaggcgagtgaggcg tcatctgtggcagagatgggccacatgggccagggggacaaggcagaggcagatctgatg gctgagctgcttaacatccaaaccaagagccaggggggaaagcatgcgcccgagccaggt ctgggggacatgggtgaggtggtgggggtcgacgccccctctttagccagtgctgtcaag cagaagaaggccaaggattacatgtgtttcttgaaggaggctgcgactaaggagcctacc aacggagaccacaaagccgagccagagaaatcagacccagaggatggggagaagaaggac caggacaaagtcaaagaggaggctcccccagagccctcaccggaggagaagaaggccccc aagaagagaccgggactgaagaaagagtctccagaggagttcatggccaacttcttctct agcctggacatctaccagaccaagatgctgaactatctggccagaaacttctacaacctg cgtttcttggcattgtttgttgcatttgccataaactttattctgctcttctacaaagtg actggagatgacggggatgacgatgatccagatccttggaatggaggtggagctactgat gaagaggaggatgaaggtgggatggagtattttgtcctgcaggagagcacaggctacatg gcacctacactgcgcttcttggccatactacacacagtcatctctttcttgtgtgtggtg ggatactactacctaaaggtgcctctggtggtgttcaagagagagaaggagatcgccagg aagttggagtttgacggcctctacatcacagagcagccgtcagacgatgacatcaaagga cagtgggaccgcctcgtcatcaacaccccttccttccctaataactactgggacaagttt gtgaaacgcaaggtgatcaataagtatggagatctgtatggagcagagaggatagcagag ctgctggggctggataagagtgctctggacttcaaccccacagaggagacagtggtgaag gaggcatcgctggtgtcctggttgagctctattgacaccaagtaccagtgctggaaaatg ggtgtggtgtttacagacaattcgttcctgtacctggtgtggtacaccaccatgtccatc ctgggtcactacaacaacttcttcttcgctgcccatctgttggatatcgccatgggcttc aagacactccggaccatactgtcctcagtcacccacaatggcaagcagctggttctgact gtaggtctcctggcggtggtggtctatctgtacactgtggtggccttcaacttcttccgc aagttctacaacaagagtgaggatgacaaccagcccgatatgaagtgtgatgacatgatg acttgctacctgttccacatgtacgttggtgtgagggcagggggtggaatcggggatgag atcgaggaccctgcaggcgacccgtatgagctctaccgcatcctcttcgacatcaccttc ttcttctttgtcatcgtcatcctgctggccatcatacagggtctgatcattgatgctttt ggagagctgagagaccaacaggaacaagtgaaagaggatatggagaccaaatgtttcatc tgtggcatcggtaatgactactttgacacgacgcctcatggctttgagacacacacctta caagagcacaacttggccaactacctgtttttcctgatgtaccttatcaacaaagatgag acagaacacaccggtcaggagtcatacgtgtggaagatgtaccaggagaggctctgggac tttttccctgctggagactgtttcagaaagcagtatgaggaccagcttggatag

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