KEGG   Salvelinus namaycush (lake trout): 120046383
Entry
120046383         CDS       T07522                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
snh  Salvelinus namaycush (lake trout)
Pathway
snh04010  MAPK signaling pathway
snh04012  ErbB signaling pathway
snh04020  Calcium signaling pathway
snh04510  Focal adhesion
snh04520  Adherens junction
snh04530  Tight junction
Brite
KEGG Orthology (KO) [BR:snh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120046383 (erbb2)
   04012 ErbB signaling pathway
    120046383 (erbb2)
   04020 Calcium signaling pathway
    120046383 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120046383 (erbb2)
   04520 Adherens junction
    120046383 (erbb2)
   04530 Tight junction
    120046383 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:snh01001]
    120046383 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:snh04147]
    120046383 (erbb2)
   04090 CD molecules [BR:snh04090]
    120046383 (erbb2)
Enzymes [BR:snh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     120046383 (erbb2)
Protein kinases [BR:snh01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   120046383 (erbb2)
Exosome [BR:snh04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   120046383 (erbb2)
CD molecules [BR:snh04090]
 Proteins
  120046383 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Tcell_CD4_C Kinase-like
Other DBs
NCBI-GeneID: 120046383
NCBI-ProteinID: XP_038847495
UniProt: A0A8U0QQ44
LinkDB
Position
Sna4:complement(25953497..25997432)
AA seq 1306 aa
MEAARSFLFLRLLLVGLSGALGREVCLGTDMKLALPSSLENHYETLRLLYTDCQVVHGNL
EITHLRGKPDLSFLQGIVEVQGYVLIARVSVSVVPLDNLRIIRGSQLYNSSYALAVLDNT
LPQEGVGLRVLRLRSLTEILLGGVHIWGNPQLCFPDPQHMEWRDTLDEKNTHAKQLRLQA
RAPNCPKCSPACVKRSCWGETEKDCQTLTHVHCASGCLRCKGPDPNDCCHMQCAAGCTGP
KDSDCLSCRHFNDSGTCKDNCPPPTIYDPVTFVSKPNPNRKFSFGATCVKTCPYNYLAME
VACTMVCPKANQEVIITQPDGKETQTQKCEKCEGECPKVCYGLGMGDLQSSSWVSSSNVA
QFTGCNKIYGSLAFLPQSFTGDPLANMTGLTLSELDAFKNLVEITGYLYIDAWPANWTNL
SVFENLKVIRGRMLYKGVFSLGVQSIQIRSLGLRSLRSISGGLVLLHNNSQLCYTQDLPW
GTLLHPTQGPHRIVNANQDPQECVVEGRMCHLLCANGCWGPGPSQCVACVKFQRGKECVE
ECDIYQGSPREFFDSSERVCGACHSECRPINGSASCLGSGAHQCTDCLHYQDGEVCVEKC
PSGLKEEQHTVWKYSNATGHCLSCNTNCTLSCTQKDERGCPIHTKTGPGTSIAAAVGGAV
LFLILLGLLVFYLRRQKQLKRKETLRRILQEHELVEPLTPSGALPNQAQMRILKETELKK
LRVLGSGAFGTVYKGAWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYV
CRLLGICLTSTVQLVTQLMPYGCLLDYVRENKDHIGSQYLLNWCVQIAKGMSYLEDVRLV
HRDLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQ
SDVWSYGVTVWELMTFGAKPYDLIPARDIPELLEGGERLPQPLICTIDVYMIMVKCWMIE
PDSRPKFKELVTEFSAMARDPPRYVVIQNDDKMSLSSPVDSQFFRMLLEEEGAEIRDLLD
AEEYLVPQPNFFRPQAETSGPNGPSRHHSHRSTDQGLDSEPSMAGGPRSMYSSVSTLGRS
QYPTLPMGASAISNGPWNPHYPSLLARTTSHLSTGGHSDSVFLDGGPDDAPASPGRYCKD
PTFPNGGESDLETDGPSPMHHYNHLNHHSLPRRGNAYNHNHALPEYINQEVQDLRPGAVE
RPSTLPRKGAAERHRHLPNGLSSGHSVENPEYLVPMMTSGSTSPAFDNPYYLDLVAKAVA
GGGGGGERDGGPNPPPRQVNDFVTPTAENPEYLGLADTWSGQREHT
NT seq 3921 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagttttctgtttctccggttactgctggtcggactttcgggcgca
ttgggcagagaagtgtgtctgggcacagacatgaagctggccctgccctccagtctggag
aaccactatgagaccctgcggctgctctacactgactgccaggtggtgcacggcaaccta
gagatcacacatcttcggggcaagccggacctctccttcctacagggtatcgtggaggtg
cagggctacgtcttgattgcccgtgtgtctgtgagtgtggtgccgctggacaacctgcgc
atcatccggggaagccagctgtacaactccagctatgctctggctgtcctggacaacacc
ctccctcaagaaggggtgggtctgagggtgctccgcctccgcagtctcacagagatcctg
ctgggtggagtgcatatttggggaaacccccagctctgtttcccagacccccagcacatg
gagtggagggacacactggatgaaaagaacacgcatgccaagcagctccgcctgcaggcc
cgggcccccaactgtccaaagtgctcccctgcctgtgtaaagcgaagctgctggggagag
acggagaaagactgccagaccctgacccatgtgcactgtgcatcggggtgtctgcgctgt
aagggacccgatcccaatgactgctgccacatgcagtgtgctgccggttgcactgggccc
aaagactcagactgcctgtcgtgccgtcacttcaacgacagcgggacgtgtaaagacaac
tgtccgccccccaccatctacgacccggtcaccttcgtgtccaaacccaaccccaacagg
aagttcagcttcggggccacctgcgtcaagacatgtccctataactacctagccatggag
gtggcctgtaccatggtgtgtcctaaagctaaccaggaagtgattatcacccagcctgac
ggcaaggagacacagacacagaagtgtgagaagtgtgaaggggaatgtccaaaagtgtgc
tatgggctgggcatgggtgatctccagagctcctcctgggtgagctcctccaacgtggcc
cagttcactggctgcaataagatctatggcagtctggctttccttccacagagcttcaca
ggggacccattggctaacatgacaggtctgacccttagtgagctggatgcatttaagaat
ttggtggagatcacaggatatctgtacattgatgcgtggccagccaactggactaacctg
agtgtgtttgagaacctgaaagtgatccgaggaaggatgctctataaaggagtgttctct
ctgggggtccagtcaatacagatccgttctctgggtctgcgttcactcaggagcatcagc
gggggtctggtcctgctccacaacaactcccagctctgctacacccaggacttgccctgg
gggaccctgctgcaccccacccaggggccccaccgaatcgtcaatgccaaccaggacccc
caggagtgtgtggtggagggccgtatgtgtcacctgctgtgtgctaatggctgctggggg
ccagggcccagccagtgtgtggcctgtgtgaaattccagcgtgggaaggagtgcgtggag
gagtgcgacatctatcagggttccccgagggagtttttcgacagctccgagagagtctgt
ggcgcctgtcactcagagtgtcgccccatcaatggctctgcctcctgcctaggctcgggg
gcccaccaatgtacagattgcctgcactaccaggatggggaggtgtgtgtggagaaatgt
cccagtggattgaaggaggagcagcacactgtgtggaaatacagcaacgccacgggccac
tgcctctcctgcaacaccaactgcactctctcgtgcactcagaaggatgaaagaggctgc
cccatccatactaaaacagggccgggcacttcgatcgcggctgcagtgggcggggcggtg
ctcttcctcatcctattgggtctgctggtgttctacctacgccgacagaaacagctcaag
aggaaggagacattgaggaggatcctccaggagcatgagctggtggagcctctgactccc
agcggagccctgcccaatcaggcccagatgcgcatcctcaaggagacagagctaaagaag
ctaagagttctgggctcaggagccttcggcactgtctacaagggggcgtgggcgcctgat
ggggagaatgtgaagatcccggtggccatcaaggttttgcgggagaacacctcacccaag
gccaacaaggagatcctggatgaggcgtacgtaatggccggtgtggccagtccctatgtg
tgtcgtctgctgggtatctgcctgacctctacagttcagctggtcacccagctcatgcca
tacggctgcctgctggactacgtccgagagaacaaggaccacatcggctcccaatacctc
ctcaattggtgtgtgcagatagcgaaggggatgagctacctggaggatgtgcgtcttgtg
cacagggacctggcagcacgtaacgtcctggtaaagaaccccaaccacgtcaagatcact
gacttcggcctggctcgcctgttggacatagacgaaacagagtaccatgcagacggaggc
aaggtgcctattaagtggatggcgttggagtctatcctccacaggaagttcacccaccag
agtgatgtgtggagctacggggtgactgtttgggagctgatgacctttggggccaagccc
tatgacctgatcccggcacgagacatcccagagctgctggaggggggcgagaggctcccc
cagccccttatctgcaccattgacgtctacatgatcatggtcaagtgctggatgattgaa
ccagacagcaggcctaaattcaaggagctggtgacagagttcagcgccatggcacgagac
ccacctcgctacgtagtcatccagaatgatgacaagatgagtttgtccagtccggttgac
agtcagttcttcaggatgctactggaggaggagggagcagaaatcagagacctgctggat
gctgaggagtacttggtgccccagcccaacttcttcagaccccaagcggagacctcgggc
cccaacggcccctcacgacaccactcacacaggagtacggaccagggattggacagcgag
ccctccatggcgggcggcccgagaagcatgtattcctcggtgagcaccctggggcgcagc
cagtaccccactctgcccatgggggccagcgccatctccaacgggccctggaacccccat
tacccctccctcctggcccgcaccacctcacacctctctacggggggacactcggactct
gtgttcctggacgggggtcccgatgacgccccagcgagccccgggcgctattgcaaagac
cccaccttccccaatggaggagagagcgacctggagacggatggaccgtcaccgatgcat
cattataatcatcttaatcatcactcgctgccccgtaggggtaatgcgtataatcataat
cacgcgttaccagagtacatcaaccaggaggtgcaagacctccggccgggggccgtcgag
cgccccagcaccctgccccgcaagggggcagccgagaggcatcggcacctccccaatggc
ctgagctcgggacacagcgtggagaacccggagtacctggtccccatgatgacctccggc
tccacctcccctgccttcgacaatccctactacctggacctggtggctaaggctgtggcc
ggagggggtggtggtggggagagggatgggggccctaaccctcctcccaggcaggtgaat
gactttgtgacgcccacggcagagaacccagagtacctgggcctagcagacacctggagc
ggccagagagagcacacctga

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