Streptomyces nigrescens: HEK616_04190
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Entry
HEK616_04190 CDS
T08756
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
snig
Streptomyces nigrescens
Pathway
snig00860
Porphyrin metabolism
snig01100
Metabolic pathways
snig01110
Biosynthesis of secondary metabolites
snig01120
Microbial metabolism in diverse environments
snig01240
Biosynthesis of cofactors
Module
snig_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
snig_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
snig00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HEK616_04190
Enzymes [BR:
snig01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HEK616_04190
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GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
BDM66932
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Position
481828..483204
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AA seq
458 aa
AA seq
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MHDQQQQQEHGERETRTAPATGPAAGPQEPQEPQEPQEPQGTHGAPGTREAAPEPGPGTG
PVTAPGTGPEAGPGDGSGPGAAPVRPLDGFTVGVTAARRAEELGALLERRGAQVMHAPAL
RIVPLPDDTELLAVTRALIGHAPDVVVATTAIGFRGWIEAAEGWGLGEALLDRLTGVELL
ARGPKVRGAIRAAGLTEKWSPASESMAEVLDRLLAEGVSGRRVAVQLHGEPLPGFVEALR
AGGAEVIGVPVYRWMPPEDLGPVDRLLDAVVGGGLDAVTFTSAPAAASLLRRAEERGIRE
EVLAALRQGVLPVCVGPVTALPLEAEDVPTLQPERFRLGPLVQLLCRELPGRARPLPVAG
RRLEIRGHAVVVDGALRPVPPAGMALLRALARRPGWVVSRAELLRVLPGSGRDEHAVETA
MARLRVALGAPKLIQTVVKRGYRLSLDPHADTDKYGAA
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgcacgatcagcagcagcaacaggagcacggcgagcgggagacgcggacggcacccgcc
accgggccggcagcgggaccccaggaaccccaggaaccccaggaaccccaggaaccccag
ggaacccacggagccccggggacccgggaagccgcgccggaacccgggccgggaaccgga
ccagtgaccgcgccgggaaccgggccggaagccgggcccggggacggttccgggcccggt
gctgcccccgtgcggccgctggacggcttcaccgtcggcgtgaccgcggcccggcgggcc
gaggagctcggtgccctgctggagcggcgcggcgcgcaggtgatgcacgcgcccgcgctg
cgcatcgtgccgctgccggacgacaccgaactgctcgcggtgacccgggcgctgatcggt
catgcgccggacgtcgtcgtggccaccacggccatcgggttccgcggctggatcgaggcc
gcggagggctgggggctgggcgaggcgctgctggaccggctgaccggcgtcgaactgctc
gcgcgcggcccgaaggtacggggcgcgatccgggccgccgggctcaccgagaagtggtcc
ccggcctcggagtcgatggccgaggtgctggaccggctgctggcggagggggtgtccggg
cggcgggtggccgtacagctgcacggcgagccgctgcccgggttcgtggaggcgctgcgg
gccggcggcgcggaggtgatcggcgtcccggtgtaccgctggatgccgccggaggacctc
ggtccggtcgaccggctgctggacgcggtggtcggcggcggcctggacgcggtgacgttc
accagcgcacccgccgccgcgtcgctgctgcgccgggccgaggagcgcggcatccgggag
gaggtgctggcggcgctgcggcagggcgtgctgcccgtgtgtgtggggccggtgaccgcg
ctgcccctggaggccgaggacgtgcccacgctccagccggagcgcttccggctggggccg
ctggtgcagctgctgtgccgcgaactgcccgggcgggcgcggccgttgccggtggccggg
cggcggctggagatccgcgggcacgcggtcgtggtggacggcgcgctgcggccggtgccg
ccggccggcatggcgttgctgcgggcgctggcccgccgccccggctgggtcgtctcccgc
gccgagctgctgcgggtgctgccggggtcggggcgggacgagcacgccgtggagaccgcg
atggcccggctgcgggtggccctgggcgcgccgaagctgatccagaccgtggtcaagcgg
gggtaccggctgtcgttggacccgcacgccgacacggacaagtacggcgcggcgtaa
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