Streptomyces nigrescens: HEK616_70340
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Entry
HEK616_70340 CDS
T08756
Symbol
pdhA_2
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
snig
Streptomyces nigrescens
Pathway
snig00280
Valine, leucine and isoleucine degradation
snig00640
Propanoate metabolism
snig00785
Lipoic acid metabolism
snig01100
Metabolic pathways
snig01110
Biosynthesis of secondary metabolites
snig01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
snig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HEK616_70340 (pdhA_2)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HEK616_70340 (pdhA_2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEK616_70340 (pdhA_2)
Enzymes [BR:
snig01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HEK616_70340 (pdhA_2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
BDM73547
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Position
7769381..7770598
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AA seq
405 aa
AA seq
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MTVEGTAQRKNTRGSSKRTTAKKATPAKKASPAKARTNGRPDQAEQDQLVQLLTPEGKRV
EHPDYAIDLSPEELRGLYRDMVLTRKFDAEATTLQRQGELGLWASLLGQEAAQIGSGRAL
RDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHAT
GYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEK
QTRVPLYQRARGYGFPGVRVDGNDVLACLAVTKAALERARTGQGPMLIEAFTYRMGAHTT
SDDPTRYRGDEERVAWEAKDPILRLRTYLEAEGLVDEAYLATIDEESEALGVRVREAVRA
MPDPDHMAIFENVYADGHALVDEERAQFAAYQASFVDADVLAEGN
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggaaggcactgcgcagcggaaaaacacccgcggcagcagcaagcgcaccacc
gccaagaaggcgacgcctgccaagaaggcgtccccggccaaggcccgtaccaacggccgg
cccgaccaggcggagcaggatcagctcgtacaactgctgaccccggaagggaagcgggtc
gagcaccccgactacgccatcgacctttcccccgaagaactgcgcggcctctaccgcgac
atggtgctgacgcggaagttcgacgccgaggcgaccaccctccagcgccagggcgagctg
ggcctgtgggcctcgctgctgggccaggaggccgctcagatcggttccggacgcgcgctg
cgcgacgacgactacgtcttcccgacgtaccgcgagcacggtgtggcgtggtgccgcgga
gtcgacccgacgaatctgctgggcatgttccgcggtgtcaatcacggcggctgggacccg
aacagcaacaacttccacctctacaccatcgtgatcggttcgcagacgctgcacgcgacc
ggctatgcgatgggtgtccagaaggatggcgcggattccgcggtcatcgcgtatttcggt
gacggtgcctccagccagggcgatgtcgcggaatccttcacgttctccgcggtgtacaac
gcccccgtcgtgttcttctgccagaacaatcagtgggccatttccgaacccaccgagaag
cagacccgggtgccgctctaccagcgcgcccgcggctacggattccccggcgtacgggtc
gacggcaacgacgtgctggcctgtctcgcggtgaccaaggcggcgctggagcgggcgcgc
accggccagggcccgatgctgatcgaggcgttcacgtaccggatgggcgcgcacaccacc
tccgacgacccgacgcgctaccgcggggacgaggagcgggtggcctgggaggccaaggac
ccgatcctgcggctgcggacgtacctggaggccgagggcctggtcgacgaggcgtacctc
gcgaccatcgacgaggagagcgaggccctgggcgtgcgggtccgcgaggccgtccgcgcc
atgcccgacccggaccacatggcgatcttcgagaatgtctatgccgacgggcacgcgctc
gtcgatgaggagcgcgcgcagttcgccgcgtaccaggcgtcgttcgtcgatgccgatgtc
ctggcggaggggaactga
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