KEGG   Streptomyces nigrescens: HEK616_75210
Entry
HEK616_75210      CDS       T08756                                 
Name
(GenBank) non-ribosomal peptide synthetase
Organism
snig  Streptomyces nigrescens
SSDB
Motif
Pfam: Condensation AMP-binding PP-binding AMP-binding_C
Other DBs
NCBI-ProteinID: BDM74034
LinkDB
Position
SNP1:76616..96694
AA seq 6692 aa
MTSSKEGRAAALPQDLQEALRRRLAGKAGGPAAGARPGIPRADRSRPLPLSFAQQRLWFL
DQLRPGDARYNSAVALRLTGDLDRTALSRALDAVVERHEALRTTFDDHDGRPVQTVQPPA
PVPLPLRDLAGEPERACEESPEAALDALLLAEYSRPFDLRTGPLLRALLIRTAPDQHVLL
LTAHHIVTDGWSMGVLLDELRTLHDAFAVGETPALAPVATQYPDFAGWQRDRLSGALLQE
QLSYWTKQLDGAVPLELPLDRPRDGAEPAGGAVHTFHVPPPTTARLRQVAADQHTTLFAA
LIAGCQALFARWSGQDDITLGSLTPGRGRTELERAVGFFVNTVVLRCPVDTARPYRDLLD
TAAATVLDAFAHDDTPFERLVEAVGTTREAGRNPLFDVMVLLHPAPPAAPGLRGLTAENV
PVPRRSATFDLSVEFVPDGDGLTGLLEYRTDLFDAPTAARMAEQLVLLLDGVAAEPDRPL
GELPLLAEDDRRRLTTEWNDTAVPVAPATYPGVFEARAARTPHHTALVAGDTTLDYAELN
ARANRLAHHLIHRGAGPERLVALRLPRTADLVVALLAVLKSGAGYLPLDPELPAERVEFL
LADARPMLVLDEAALRAVPGDTPATNPTDADRRAPLHPGHPAYVIYTSGSTGRPKGVAVE
HRSLMNLLAAHEHGFVADAGGGPLRVALTASFSFDTSLEGVLLMAGGHQLHLVDETTRLD
PAALVEYVVTHRLDFLDLTPSYLRQLLPAGLLSDPRHRPRVLMLGGEAVGPALWRELSAL
PDTAAYNFYGPTECTVDALACRITGTGRPLVGRPLANVRAYVLDDRLQPVPPGVGGELYL
AGAQIARGYLHRPGLTAARFTADPYGPPGSRMYRTGDLARWTADGRLDYLGRADDQVKIR
GHRIEPGEIEAALLALPDVAEAAVLAVENDQGHARLAAYVAPSATGRPTPSGLRDALART
LPGHMVPAAFVVLDALPLNSSGKLDRRALPAPDLDAAPREREFVAPRTPAERELAAIWSE
VLGLARVGVTDNFFELGGDSILSIQAVSRARAAGWLLTSRDVFRHQTVADLAAAVTPRTA
PATAPRPQQDTGPAPLTPIQEWFFATHGPQRHFTMSMLLDLPHDLDRLALEQALHAVAAH
HPALRTRFLRTGDTWRQHPGAPVAPGLLTRHDLSGTSGTARDAARTEAADAARAALDPAA
GTLLRAVLFLPDPGDRPQLFLTAHHLAVDSVSWRILLADLETAYRQAAAGRPVQLAPTGT
PFTTWAASLVRHVQDGGLDDDLAHWSAQSAVPRTPLPADRDGTPVAGSVRTVRARLDRDT
TEALLRRVPGVYRTQVNDVLLSALGRVLADWTGTDRVTVALEGHGREDLGGTEGDAGAGD
AAAADAPDLSRTVGWFTTQYPVTLTPAGPADEPDWGGTLKAVKEQLRAVPRRGLGYEALA
RLGSPDPAARALQAQPLPEVCFTYHGQWETPQDADFAPAGPAPGRDLAADARLDHLLDVS
AVVADGVLELTWHYSDQVHHERTVRDLADGTVRALTGIVAHCARPDAGGRTPSDFPLAQL
DQAGLDRLVGDGHGIEDLYPLTPLQEGMLFHRLVGQDGGNGGDGGSGDVYLDQAALLLDG
VTEPETFARAWQRVADRNPVLRTSVVWDGVPAPLQIVHRRATVPVVHLDWRDLDDATRAD
RLARLRADDLAQGLDLGTAPLMRLTLIRLPGGQLRLLWTSHHLILDGWSLAQVLTEVCEE
YAALATGRDATPPVRRPFADYVRWLATRDGRAAEQHWRTVLAGFATPTPLPCDRPPREAH
RARSAEVVAAGLTPERSRALEDTARRAGLTLNTVVQGVWALLLARYSGDPDVVFGSTVSG
RPDELPGAEAMVGMFINTLPTRARVEGHRTAADWLRDLQDAQSESRRFETVSLAQLTSLS
DVPAGTALFDSMVAFENYPFDEARTSGAGVRILDVTSLDATNFPLVLRAHHGDRLGFDLA
YDPGLFDEATVRSLADRLCLLLDEIAAGPERPLRDLAWTTAEERRRMLVDWNGSAHGRPE
RTLVDLFEDQAARTPDATAVTCAGDTLTYAELDARAGWLAHRLAASGAGPERFVALALPR
STDMLVAIVAVLKTGAAYVPVDPELPGDRITHLLTDAAPALLVTTTAATGRLGDTAVPRL
LLDDPEVRADLARRPAAALAPEHRPLPESPAYVIYTSGSTGRPKGVVVPHANVVRLFSGA
RDRFGFDAHDVWTLFHSYAFDFSVWEIWGALLHGGRLVVVPHDIARSPADFLRLLADERV
TVLNQTPSAFYPLMRADAEHTDLSGELTLRYVIFGGEALDLGQLTDWYERHPDTAPALVN
MYGITETTVHVTHAPLDRATVAGATGSAIGSGLPDLRLHVLDAGLAPVPPGAVGELYVAG
EGLARGYLNRPGLTAARFVAHPFGPPGSRMYRTGDRVRWRRDGTLEYLGRADQQVKIRGF
RIEPGEIEAALNAHPAIGASVVSVREDTPGVRRLVAHVVGTGPDAPPSAAALRAHLERTL
PAHMVPAAYVPLDALPLTVNGKLDHRALPAPGPDGYATGGRRTAPRTAAERLVAGAWAEV
LDTEEIGVEDSFFALGGDSILAIRVTSRLRAAFGVDVSPRLLFTRPTVAALAAALPDPAA
DRRPPADPIPPADRDRALPLSFAQQRLWFLDHFEPGSTEYLTFFVLRLRGRLDEAALHTA
LDALVARHEPLRTTFAEQDGRARQQVHPPHPVDLPTHDLSAVPADARPGALDELLADEAA
TPFDLGHGPLLRTRLIRLAPDEHVLTLALHHIVTDGWSTAVLGRDLGELYAAALEDRRPD
LPPLPVQYADYAAWQRARSADAERQLDYWKEQLADVAPLELPTDRPRPAVRTKNGALLEF
ALPAALTDRLRETGRRTDATLYMTLLAACQVLLARWAGQEDIAVGTVTAGRDRPELEHLV
GMFVNTLVLRGRVRTDEPFDALLSRVRGTVLDAFAHQDVPFERVVDALQPERDTSRTPLF
QVMVALHNLGGRAPQLPGLDVETVQPPGRSATFDLGLDFVEQDGGGLTCFVEYHTDLFDR
DTVERLTGRLRLLLEAVADDPGRPVGELPLLSDAERHQVLEEWQGAALHVPDTTFPELFE
AQAARTPHATALVARDATLDFAELNTRANRLAHHLIALGVGPERVVAVQLPRTSEMFVAL
LAVLKAGGTQLSVDPELPADRVAYLLADAAPQTVLTPEALRDAPLDRQPTHNPTDADRIA
PLHPAHTAYLTYTSGSTGRPKGVAVEHRQLVNLCHDHRDGLVAPHTTDGTPLRAALSAAF
SFDTSWEGPLLLALGQQVHLIDEDVRLDPAAFVARIAAHRLDFLNVTPSFLHELLAAGLF
TTGGHRPRIVLVGGEAVGTAAWQQLRALPGVTAYNIYGPTECTVDAVYGRFTDHATHPVI
GRPGRNLRAYVLDGSLRPVPVGVPGELYLAGAQVARGYRGRPGLTAGRFVADPFGPPGTR
MYRTGDRARRHPGGLLEFLGRTDDQVKIRGFRIEPGEVEAALLDHPEVGDAVVAARTQAG
RTMLVAYVVPRGGRQPAADALRVHLRRTLPDYMVPAAFVPLARVPRTSSGKTDRRALPAP
PLQPDTDTPYVAPRTGTETLLAGIWAEVLGTPRIGVEDNFFALGGDSILSIQIVSRARQA
GLALTSKDVFRHQTVAELALRTDQVAAPPAADATAPAGPAPLTPIQRWYLDGRRPGDRLH
FTMTQRLELAPGTDPEALRRAVDTLISHHPALRTRFRRTDGTWHQEVLPAAPGDAFAHHD
LTGLDDRAQEDAVQRAAADAQTSLDPTEGRVLRALLFDRGPGRPPQLVLTAHHLVVDGVS
WRILLADLEAAHRNASAGRPAALPPASTGYPQWADRLQRHTRSGAFDGDLPYWTRVCGTP
ADLPVDRPGAHPRGAAATVTVRLGRDATDALLRQVPDVYRTQVNDVLLSALGRTLSRWSG
RDTVLLGIEGHGREDLFDDLDLSRTVGWFTAEFPLALTVDPDADWRDTVRSVKEQLRAVP
LRGLSYGALRHLAPQAPLPDAPRPRIGFNYHGQWDVAATDRPADDGLYRAALPPAGQDTD
PDEERSYLLDVTGVVQDGRLELGWTYPPAVYDEATVRRLAEDTLAALDEIVAHCARPDTG
GRTPSDFPLAGLDQHQVDLLAGDGRDVVDIHPLTPLQAGMLFHQLVDDAGAYFDQMAVRI
AGIADPHAFAAAWQRVADHTPALRSSVHWHGLPHPVQVVHRHADLPVTHHDWRTLTPGER
DRAQEKLLAEERATGVDLTRAPLSRIAVAALPDDEIVLVWSSHHLMLDGWSTGQIFTDVC
AQYAAAARGTTLRPPARRPFRDFLQWLADQDEEQAERHWADALGGCTARTPLPYDRRPAE
AHRARATDSVAVELTPEVSDRLRTMAGRHGLTVNTVVQGAWALLLARSGGRRDVVFGTTV
SGRPAELAGVASMVGMFINTVPTRARIDGARTVPDWLRDLQEQQSDSRRYDFVSLARIQA
LSELPAGEPLFDSMVVFENYPFDETAAADAGIRITDVRADDAPTFPLCLRAYLADRLGFG
LAYDPALFDRATVERTADRLRALLTAVADGAARTVDDLDPLTDADRALLHRWNTPARQTS
PGSPVTLFAEQVRRTPDALAVSDDEQELTFRQLDEWADKLAHRLRAAGLPAEGRVALLMD
RSVALVVAQLAVLKAGGAYVPVDVRAPEERRRTLLRQAGVTVQLTDRDVTDARADGPAGP
PPAAATDPDCLAYVMFTSGSTGEPKAVGVRHRDVAALATDSRFRGPDCQRVLLHSPVAFD
AATFEVWAPLLNGGRIVVAPPGAVNAALLRRLADGGEVTALWLTAGLFRLLAQDAPDCFA
GLRQVWTGGDVVPAAAVRRVLDACPGLTVVDGYGPTETTTFATTHAMTDAAAVPDPVPIG
RPLDDMRVHVLDARLRPVPPGTVGELYLAGEGVARGYLGRPGASAERFLADPSGPPGTRM
YRTGDLARRHPDGTVEFLGRADDQVKIRGFRVEPGEVEGALAAHPAVADVAVVAREGRSG
AKQLIAYVVGHDGLDPDALHAHARRTLPDYLVPTAVVPLDALPLSTNGKVDRAALPAPDA
PTGRPEAVAPRTDAERRIAAIWSDVLGVPEVGVTDDFFALGGDSILSIRLTSRLAEAFGT
ELTPRAVFSHPTPAALAVLLTAPGQPAGRPGAALVPVGRDTPLPQSFAQQRLWFLDSFAP
ESTEYLTPLALRLRGRLDTTALAAALTALATRHESLRTTFDSVDGQGVQIVHPPQDVPLP
LHDLTELPPGDRPARLTQLLAEERTRPFDLRRGPLLRAGLIRLADDHHVLTLTLHHIVTD
GWSTGILTGDLAHLYRAALTGTPATLPALPVQYADVAQWQRTALTGPAAEDQLRWWKERL
TGIEPLQLPTDRPRPPVRTRHGATTGFVLPPETARRLAEFGRTRQTTLFMTLVAAVQTLL
ARLSGQRDIAVGTVTSGRERPETQRLIGFFVNTLVLRSTVEPERSFPDFLADVRDTVLDA
FAHQDVPFERVVDEVQPDRDTSRTPLFQAMVVLQNAPGAPMDLPGLRVSDIEPERDEAAF
DVTLEFAEADSGALHGLLTYHSDLFDADTARRMADQLTTLLTALADDPDRPLGALPLAPA
EELRRLLTDRQGDAHRVPPATLPELFARQVTRRPDAPALAEGDRVLTYAELDTAANRLAH
RLISRGVGPERLVALALPRGADMVVAQLAVAKAGGAFLPVDPAYPAERREFMVRDSAAAL
VLDDPADVWCPDGPATAPTAADRPAPLTTDHPAYVIYTSGSTGTPKAVVVTHTGLAGFAA
AAADRYDVQPGDRILQFASPSFDASVLELCISLLAGATLIAGEEGPLVGDRLAQVLADRR
ITHTLIPPAALATVPPETAGTLPDLRTLIVGAEACPADLVDHWAPGRRMINSYGPTEATV
VATWTGPLTPGAGAPPIGHTVDGTRAYVLDAALRPVPVGVTGELYVAGAGLARGYLARPG
LTAARFPADPFGPPGSRMYRTGDLVRWGADGQLRYAGRADDQVKVRGYRIEPGEIESALR
RAPQVRDAAVVVRSTGPSGAEPPAPGRLVAYVVPADGPPDALDVQELRADLAHTLPSHMV
PSVFVPLAELPLTPNGKTDRRALPAPAPSTVPTAHHIAPRTDTERRIAQIWAEVLGLDTV
GADDNFFALGGDSILSMQVVSRLRRTGLHLATKDLFTHQTVAELATVVTTGPDRADDGPV
TGDLPLTPIQHWFLTTPRANHHHFNQSALLELDGEPDPTALEAALTALLTHHDALRLRFT
EQDGRWHQHNPPPPATPDRLLVRHDLTGLTPDQTDTALRTTADTLHTGLDIGRGPLLRAA
LLTGGRDHPGYLLLVAHHLVIDAVSWRILLDDLDTAYHQAAQGHPVTLGARTTSFRDWAR
GLAAHVAAGALDHELPYWEEALNSAPLPVDHTPEPATTAETRTLTRTLDEPDTTALLRAA
PTAYRTRINDVLLAALALALARWTDRDRVSVDLEGHGREDVLDGVDLSRTVGWFTTVHPV
GLHIPDRADLGPTRDWRALVKSVRRQLRTVPGNGLGFGALRTYGSPDIRRRLERTGHGRL
VFNYLGQWDSRRTGTDTGGGLIRAEHGSFGQDHDPRDPGSHLLEAVGAVQNGRLTFTWHY
RPDTHEETTVRAVAEDFTEALHQIARHARNSL
NT seq 20079 nt   +upstreamnt  +downstreamnt
atgacgtcttcgaaggaaggccgcgccgcggccctgccgcaggacctccaggaagccctg
cgccgtcgcctcgccggaaaggccggcggcccggcagcaggcgcccggccgggcatcccc
cgcgccgaccggtcccggccgctgccgctgtccttcgcccagcagcggctgtggttcctc
gaccagctgcggcccggcgacgcccgctacaacagcgcggtcgcgctgcggctcaccggc
gacctggaccgcaccgcgctgtcccgggcgctggacgccgtggtcgagcgccacgaggca
ctgcgcaccacgttcgacgaccacgacggccggcccgtgcagaccgtgcagccgcccgcc
ccggtgcccctgccgctccgggacctcgcgggggagccggagcgcgcgtgcgaggagagc
ccggaggcggcgctcgacgcgctgctgctcgccgagtactcccgcccgttcgacctgcgc
accgggccactcctgcgcgccctgctgatccgcaccgcgcccgaccagcacgtcctgctg
ctcaccgcgcaccacatcgtcaccgacggctggtcgatgggcgtgctgctggacgaactc
cgcaccctgcacgacgccttcgccgtgggggagacgcccgccctggcgccggtggccacg
cagtaccccgacttcgccgggtggcagcgcgaccggctgtccggcgccctcctccaggag
caactgtcctactggaccaagcaactggacggcgcggtaccgctggagctgccgctcgac
cgtccccgcgacggggcggaaccggccggcggcgcggtgcacaccttccacgtcccgcca
ccgaccacggcccgcctgcggcaggtggcggccgaccagcacaccaccctcttcgccgcg
ctgatcgccggctgccaggccctgttcgcccgctggtccgggcaggacgacatcaccctc
ggatccctgacccccgggcgcggccgcaccgaactggagcgcgcggtcggcttcttcgtc
aacacggtcgtgctgcgctgcccggtcgacaccgcccgcccctaccgcgacctgctggac
accgcggccgccaccgtcctcgacgccttcgcgcacgacgacaccccgttcgaacggctg
gtggaggcggtcggcacgacccgggaagcgggccgcaacccgctcttcgacgtcatggtc
ctgctccaccccgccccgcccgccgcccccggcctgcgcgggctgaccgccgagaacgtg
cccgtgccccgccgctcggccaccttcgacctcagcgtggaattcgtgcccgacggggac
ggcctcaccgggctgctggagtaccgcaccgacctcttcgacgccccgaccgcggcgcgg
atggccgagcaactcgtcctcctgctcgacggggtggccgccgaacccgaccggccgctg
ggcgagctgccgctgctcgccgaggacgaccggcggcggctgaccaccgagtggaacgac
accgccgtgccggtcgcccccgccacctaccccggcgtcttcgaggcccgggccgcccgc
accccgcaccacacggcactggtcgccggtgacaccaccctggactacgccgaactcaac
gcccgcgccaaccggctggcccaccacctcatccatcgcggcgccggccccgaacggctc
gtcgcgctgcggctgccgcgcaccgccgacctggtcgtggccctcctcgccgtcctcaaa
tccggtgccggctacctgcccctcgaccccgaactgcccgcggaacgcgtggagttcctg
ctcgccgacgcccggccgatgctggtgctcgacgaggccgcgctgcgcgccgtacccggc
gacacgcccgcgacgaaccccaccgacgccgaccgccgcgccccgctgcaccccggccac
cccgcctacgtcatctacacctccggctcgaccggccgtcccaagggcgtcgccgtcgag
caccgctccctgatgaacctgctggccgcacacgagcacggcttcgtcgccgacgccggc
ggcgggcccctgcgggtcgccctgaccgcgtcgttctccttcgacacctcgctggagggc
gtcctgctgatggccggtggccatcagctgcacctcgtcgacgagaccacccggctcgac
ccggccgcgctggtcgagtacgtcgtcacccatcgcctcgacttcctcgacctcaccccc
tcctacctgcggcaactgctgcccgccggattgctcagcgacccccgccaccggccccgg
gtgctgatgctcggcggcgaggccgtcggccccgcgttgtggcgggagctgtccgcgctg
cccgacaccgccgcgtacaacttctacggcccgaccgagtgcaccgtcgacgcactggcc
tgccgcatcaccggcaccggccggcccctggtgggccggccgctcgccaacgtgcgcgcc
tacgtcctcgacgaccggctgcagccggtgccgcccggtgtcggaggcgagctctacctc
gccggcgcccagatcgcccgcggctatctgcaccgccccggcctgaccgccgcccgcttc
accgccgacccgtacgggccgcccggcagccggatgtaccgcaccggcgacctcgcccgt
tggacggccgacggacggctcgactacctgggccgcgccgacgaccaggtcaagatccgc
ggccaccgcatcgaacccggcgagatcgaggcggccctgctggccctgccggacgtcgcc
gaggcggccgtcctcgccgtcgaaaacgaccagggccacgcccggctggccgcctatgtg
gcgccctccgccaccggacggcccaccccgtccggcctccgcgacgccctcgcccgcacc
ctgcccggccacatggtgcccgcagccttcgtcgtcctcgacgccctgccgctcaacagc
agcggcaaactggaccggcgcgccctgcccgcccccgacctcgacgcggccccgcgcgag
cgggagttcgtcgcaccgcgcaccccggccgagcgcgagctggccgcgatctggtccgag
gtcctcggcctcgcccgggtgggcgtgacggacaacttcttcgagctgggcggcgactcg
atcctcagcatccaggcggtctcccgggcccgcgccgccggctggctgctgacctcccgg
gacgtcttccggcaccagaccgtcgccgacctcgccgccgcggtcaccccgcgcaccgcc
ccggcgaccgcgccccggccgcagcaggacaccggcccggccccgctcacccccatccag
gaatggttcttcgccacccacgggccgcagcggcacttcaccatgtcgatgctgctcgac
ctgccgcacgacctcgaccggctcgccctggaacaggccctgcacgccgtcgccgcacac
caccccgcgctgcgcacccgcttcctgcgcaccggcgacacctggcgccagcaccccgga
gcccccgtggccccgggcctgctgacccgccacgatctctccggaaccagcggtaccgcc
cgggacgccgcccgcaccgaggcggccgacgccgcccgcgccgccctggacccggccgcc
ggcaccctgctgcgcgccgtcctgttcctgcccgaccccggcgaccgcccccagcttttc
ctgacggcccatcacctcgccgtcgacagcgtatcctggcgcatcctcctcgccgatctg
gaaaccgcctaccgccaggccgccgccggccggccggtccaactggcgcccaccggcacg
ccgttcaccacctgggcggcctccctggtccgccatgtccaggacggcggtctcgacgac
gacctcgcgcactggagcgcgcagagcgccgtaccgcgcaccccgctgccggccgaccgc
gacggcaccccggtcgccggctcggtccgcaccgtacgcgcccgcctcgaccgcgacacc
accgaggccctgctccgccgggtacccggcgtgtaccgcacccaggtcaacgacgtgctg
ctgagcgcactgggccgggtcctcgccgactggacgggcaccgaccgggtgacggtggca
ctggagggccacggccgggaggacctcggcggcaccgagggtgacgcgggcgccggtgac
gcggccgccgccgacgcccccgacctgtcccggaccgtcggctggttcaccacccagtac
ccggtcaccctcaccccggccggcccggcggacgagccggactggggcggcacgctcaag
gcggtcaaggaacagctgcgggccgtcccgcgccgcggcctcggctacgaggcgctggcc
cgcctcggctcgcccgacccggccgcccgcgccctgcaggcccagccgctgcccgaggtc
tgcttcacctaccacggccagtgggagaccccgcaggacgccgacttcgcgcccgccggc
ccggcccccggccgcgacctggccgccgacgcccggctggaccacctgctggacgtctcc
gccgtggtggccgacggcgtgctggaactgacctggcactacagcgaccaggtgcaccac
gagcgcacggtccgcgacctggccgacggcacggtccgggcactgaccgggatcgtcgcc
cactgcgcccggcccgacgccggcggccgcaccccctccgacttccccctcgcccaactg
gaccaggccggcctcgaccgcctcgtcggcgacggtcacggcatcgaagacctctacccc
ctgacaccccttcaggaaggcatgctcttccaccgcctcgtcggtcaggacggcgggaac
ggtggggacggcgggagtggcgacgtctatctcgaccaggccgccctgctgctcgacggg
gtgaccgaaccggagaccttcgcccgggcctggcagcgggtggccgaccggaaccccgtc
ctgcgcacctccgtcgtctgggacggcgtgcccgccccgctgcagatcgtgcaccgccgc
gccaccgtgccggtcgtccacctggactggcgcgacctcgacgacgccacccgcgcggac
cggctggcccgcctgcgggccgacgacctggcgcagggcctcgatctcggcaccgcaccg
ctgatgcggctcaccctgatccggctgcccggcgggcagctgcggctgctgtggacctcg
caccatctgatcctggacggctggagcctggcgcaggtgctgaccgaggtgtgcgaggag
tacgccgccctggccaccggccgggacgcgacgccgccggtccgccgccccttcgccgac
tacgtccgctggctcgccacccgcgacggccgcgccgccgagcagcactggcgcaccgtc
ctcgccggcttcgccacccccaccccgctgccctgcgaccgcccgccgcgcgaggcccac
cgggcccgctccgccgaggtcgtggccgccggcctgacccccgagcggtcccgcgcgctg
gaggacaccgcccggcgcgccggcctgaccctcaacaccgtggtgcaaggcgtctgggcc
ctgctgctggcgcgctacagcggggatccggacgtggtgttcggcagcaccgtctccggc
cgtcccgacgaactgcccggcgccgaagccatggtgggcatgttcatcaacaccctgccg
acccgggcacgcgtcgaaggacaccgcacggccgccgactggctgcgggacctccaggac
gcccagtccgagtcccgccgcttcgagaccgtctcactggcccagctgacctcgctcagc
gacgtgcccgcgggcaccgcgctcttcgacagcatggtcgccttcgagaactaccccttc
gacgaggcccggacctccggcgccggcgtgcgcatcctcgacgtcacctccctggacgcc
accaacttcccgctggtgctccgcgcccaccacggcgaccgcctcggcttcgacctcgcc
tacgacccgggcctgttcgacgaggccaccgtccgctccctcgccgaccggctgtgcctg
ctgctcgacgagatcgccgccggccccgaacggccgctgcgcgacctggcctggacgacc
gccgaggaacgccggcggatgctggtggactggaacggctccgcgcacggccggcccgag
cggacgctggtcgacctgttcgaggaccaggccgcacgcacccccgacgccaccgccgtg
acctgcgccggcgacaccctgacctacgccgaactcgacgcgcgggcagggtggttggcg
caccggctggccgcgtccggagccggccccgagcggttcgtggcgctcgccctgccccgc
tcgacggacatgctcgtggcgatcgtggcggtgctcaagaccggcgccgcctacgtaccc
gtcgacccggaacttcccggggaccgcatcacccacctgctcaccgacgccgcccccgcc
ctgctcgtcaccaccacagcggccaccggacgcctgggcgacaccgccgtgccgcgcctc
ctcctcgacgaccccgaggtccgcgccgatctggcccggcgcccggccgccgccctcgcg
ccggagcaccgcccgctgccggagagccccgcctacgtcatctacacctcgggctccacc
ggccggcccaagggcgtggtcgtcccgcacgccaacgtggtgcggctgttctccggcgcc
cgcgaccggttcggcttcgacgcgcacgacgtgtggaccctcttccactcctacgccttc
gacttctccgtctgggagatctggggagccctgctgcacggcggccgcctggtcgtcgtc
ccgcacgacatcgcccgttcgccggcggacttcctccgtctgctggcggacgagcgggtc
acggtgctcaaccagacgccctccgcgttctacccgctgatgcgcgccgacgccgaacac
acggacctgagcggggagttgacgctccgctacgtcatcttcggcggcgaagccctcgac
ctcggccagctcaccgactggtacgagcggcacccggacaccgccccggccctggtcaac
atgtacggcatcaccgagaccaccgtgcacgtcacccacgcaccgctcgaccgcgccacg
gtggccggcgccaccggcagcgccatcggctccggcctgcccgacctgcggctccatgtg
ctcgacgccggtctcgccccggtgccgcccggtgccgtcggcgaactctacgtggccggc
gaggggctggcccgcggctatctgaaccggcccggcctgaccgccgcacggttcgtcgcc
caccccttcgggccgcccggcagccggatgtaccgcaccggcgaccgcgtccggtggcgg
cgcgacggcacgctggagtacctgggccgggccgaccagcaggtcaagatccgcggcttc
cgcatcgaacccggcgagatcgaggccgcgctgaacgcccaccccgcgatcggcgcctcg
gtggtctccgtgcgcgaggacacccccggcgtgcggcggctggtcgcccatgtcgtcggc
accggcccggacgccccgccgtccgccgccgcactccgcgctcacctggaacggaccctg
cccgcccatatggtccccgccgcctacgtgccgctggacgcgctgccgctgaccgtcaac
ggcaagctcgaccaccgggcgctgcccgcccccggcccggacggctacgccacaggcggg
cggcgcacggccccgcgcaccgccgcggaacgcctggtcgccggtgcctgggccgaggtc
ctggacaccgaggagatcggcgtcgaggacagcttcttcgcgctgggcggcgactcgatc
ctcgccatccgcgtcacctcccggctgcgcgccgccttcggcgtggacgtctcgccgcgg
ctgctgttcacccggccgacggtggccgccctggccgccgcactgcccgacccggccgcg
gaccgccggccaccggccgacccgatcccgccggccgaccgcgaccgcgcactcccgctg
tcgttcgcccagcaacgcctctggttcctcgaccacttcgaacccggcagcaccgaatac
ctgaccttcttcgtgctccgcctgcgcggccggctcgacgaggccgcactgcacaccgcc
ctggacgccctggtggcccggcacgaaccgctgcgcaccaccttcgccgagcaggacggc
cgtgcccgccagcaggtccacccgccccacccggtggacctcccgacgcacgacctgtcc
gccgtcccggccgacgcgcggccgggcgccctcgacgagctgctcgccgacgaggccgcc
acccccttcgacctggggcacgggccactgctgcgcacccggctgatccgcctcgccccg
gacgagcacgtactgaccctggccctgcaccacatcgtcaccgacggctggtccaccgcc
gtcctcggccgggacctgggcgagctgtacgccgcggccctggaggaccgccggcccgac
ctgcccccgctgcccgtccagtacgccgactacgccgcctggcaacgcgcccggtccgcc
gacgccgagcggcaactcgactactggaaggagcagttggcggacgtcgccccgctggag
ctgcccaccgaccggccccggcccgcggtgcgcaccaagaacggcgcactgctggagttc
gcgctgcccgccgcgctgaccgaccggctgcgggagaccggccggcgcaccgacgccacc
ctctacatgaccctgctcgcggcctgccaggtgctcctcgcccgctgggccggccaggag
gacatcgccgtcggcaccgtgaccgccggccgcgatcgccccgaactggagcatctggtc
ggcatgttcgtgaacaccctcgtgctgcgcggccgggtgcgcaccgatgagccgttcgac
gcgctgctgtcgcgggtgcgcggcaccgtgctggacgccttcgcccaccaggacgtgccg
ttcgagcgggtcgtcgacgcgctccagccggaacgcgacaccagccgcaccccgctgttc
caggtcatggtcgccctgcacaacctgggcggccgggccccgcagctgcccggcctggac
gtcgagacggtccagccgccgggccggagcgccaccttcgacctcggcctcgacttcgtc
gagcaggacggcggcggtctcacctgcttcgtcgagtaccacaccgacctgttcgaccgg
gacaccgtcgagcggctgaccggccggctgcgcctgctgctggaagcggtcgccgacgac
cccgggcgcccggtgggcgaactgccgctgctgtccgacgcggagcgccaccaggtcctg
gaggagtggcagggcgccgcactgcacgtcccggacaccacgttccccgagctgttcgag
gcccaggcggcccgtaccccgcacgccaccgcactggtggcacgggacgccaccctcgac
ttcgcggagctcaacacccgcgccaaccggctggcccaccacctcatcgcgctcggggtc
ggccccgagcgggtggtcgccgtccaactcccgcgcacctccgagatgttcgtggcgctg
ctggccgtcctcaaggccggcggcacccagctgtccgtcgacccggagctgcccgctgac
cgggtggcgtatctgctcgcggacgccgcaccgcagaccgtgctcacccccgaggcgctg
cgcgacgccccgctggaccggcagcccacccacaaccccacggacgccgaccgcatcgcc
ccgctgcaccccgcccacaccgcttacctcacctacacctccggctccaccggccgcccc
aagggcgtcgccgtcgaacaccgccagctcgtcaacctctgccacgaccaccgggacggg
ctggtcgccccgcacaccacggacggcaccccgctgcgcgccgcgctgagcgccgccttc
tccttcgacacctcctgggagggcccgctgctgctggccctcggacagcaggtgcacctg
atcgacgaggacgtgcggctggacccggccgcgttcgtcgcccggatcgccgcccaccgc
ctggacttcctcaatgtgacgccgtccttcctgcacgagctgctggccgccgggctgttc
accaccggcggccaccgcccccggatcgtcctggtcggcggcgaggccgtcggcaccgcc
gcctggcagcagctccgcgcgctgcccggcgtcaccgcgtacaacatctacggccccacc
gagtgcaccgtcgacgccgtctacggacgcttcaccgaccacgcgacgcacccggtcatc
ggacggcccggccgcaacctgcgcgcctacgtgctcgacggctccctgcggcccgtaccc
gtcggcgtgcccggtgagctgtacttggccggtgcgcaggtcgcccgcggctaccggggc
cggccgggcctgaccgccgggcggttcgtcgccgacccgttcggcccgcccggcacccgg
atgtaccgcaccggcgaccgtgcccgccggcaccccggcggactcctggaattcctcggc
cgcaccgacgaccaggtcaagatacgtggcttccgcatcgagcccggcgaggtcgaggcg
gccctcctcgaccaccccgaggtgggcgacgcggtcgtcgcggcccgcacccaggccggc
cgcacgatgctggtggcctacgtcgtgccgcgcggcggccggcaacccgccgcggacgca
ctccgcgtccacctgcgccgtacgctgcccgactacatggtccccgcggcgttcgtcccg
ctcgcgcgggtgccgcggaccagcagcggcaagaccgaccggcgcgccctgcccgcaccc
ccgctccagccggacaccgacaccccgtacgtggccccgcgcaccggcaccgagaccctg
ctcgccggcatctgggccgaggtcctcggcacgccccggatcggcgtcgaggacaacttc
ttcgccctcggcggcgactcgatcctcagcatccagatcgtctcccgggcccgtcaggcc
ggactcgccctcacctccaaggacgtcttccgccaccagaccgtcgccgaactcgccctg
cgcaccgaccaggtggccgccccgccggccgccgacgccaccgccccggccgggccggcg
ccgctcacgcccattcagcgctggtacctcgacggccgccggcccggcgaccggctgcac
ttcaccatgacccagcggctggaactcgcccccggaaccgacccggaggcactgcgccgc
gccgtcgacaccctgatctcccaccacccggcgctgcgcacccggttccgccggaccgac
ggcacctggcaccaggaggtgctgcccgccgcacccggggacgcgttcgcccaccacgac
ctgaccggcctcgacgaccgcgcgcaggaggacgccgtccagcgcgcggccgccgacgcc
cagacctccctggatcccaccgagggccgtgtcctgcgcgccctcctcttcgaccgtggc
cccggccgtccgccccaactcgtcctcaccgcacaccacttggtcgtcgacggggtgtcc
tggcgcatcctgctcgccgacctggaggccgcccaccgcaacgcctccgccggccgcccg
gccgccctgcccccggcgagcaccggctacccgcagtgggccgaccgtctgcaacggcac
acccgctccggcgccttcgacggcgacctgccgtactggacccgggtctgcggcacgccc
gccgacctccccgtcgaccggcccggcgcccacccgcggggcgccgccgccaccgtgacc
gtccgcctgggccgggacgcgaccgacgccctgctgcgccaggtaccggacgtctaccgc
acccaggtcaacgacgtcctgctcagtgccctgggccgcaccctgagccgctggagcggc
cgggacaccgtcctcctcggcatcgaggggcacggccgcgaggacctcttcgacgacctg
gacctgtcccgcacggtcggctggttcaccgcggaattcccgctcgccctgaccgtcgac
ccggacgccgactggcgcgacaccgtccgctccgtcaaggagcagctacgggccgtcccg
ctgcgcggactgagctacggcgcgctgcgccacctcgccccccaggccccgctgcccgac
gcgccgcggccgcgcatcggcttcaactaccacggccagtgggacgtcgccgccacggac
cggccggcggacgacgggctctaccgcgccgccctgccgcccgccggacaggacaccgac
cccgacgaggaacgcagctatctgctcgacgtgaccggcgtggtccaggacggccggctc
gaactcggctggacctacccgcccgccgtctacgacgaggccaccgtgcgccgcctcgcc
gaggacaccctcgcggcgctggacgagatcgtcgcgcactgcgcccgcccggacaccggc
ggccgcaccccttccgacttcccgctcgccggactcgaccagcaccaggtggacctgctc
gccggcgacggccgcgacgtggtggacatccacccgctgaccccgctccaggccggcatg
ctcttccaccagctggtcgacgacgccggcgcctacttcgaccagatggcggtccggatc
gccggcatcgccgacccgcacgccttcgccgcggcctggcagcgggtcgccgaccacacc
ccggccctgcgcagcagcgtccactggcacggcctgccgcaccccgtccaggtcgtccac
cggcacgccgacctgcccgtcacccaccacgactggcggaccctgacgcccggcgaacgc
gaccgggcacaggagaagctgctcgccgaggaacgcgccactggcgtggacctcacccgc
gccccgctcagccggatcgcggtggccgcgctccccgacgacgagatcgtcctggtgtgg
tcctcgcaccacctgatgctcgacggctggagcaccggccagatcttcaccgacgtgtgc
gcgcagtacgccgccgcggcccgcggcaccacgctccgcccgccggcccgccgcccgttc
cgggacttcctccagtggctggccgaccaggacgaggagcaggccgagcggcactgggcc
gacgcgctgggcggatgcaccgcccgcacgccgctcccgtacgaccggcggcccgccgag
gcgcaccgcgcccgggcgaccgacagcgtcgccgtcgaactcacccccgaggtctccgac
cggctgcgcaccatggccggacgccacggtctcaccgtcaacaccgtcgtccagggcgcc
tgggcgctgctgctggcccgctccggcggccgccgggacgtggtgttcggcaccaccgtc
tccggccgcccggccgagctggccggcgtggcatccatggtcggcatgttcatcaacacc
gtcccgacccgggccaggatcgacggcgcccggaccgtgccggactggctgcgcgacctc
caggagcagcagagcgactcccgccgctacgacttcgtctcgctcgcccgcatccaggca
ctcagcgaactccccgcgggggagccgctgttcgacagcatggtggtcttcgagaactac
cccttcgacgagacggccgcggccgacgccggcatccgcatcaccgacgtgcgcgccgac
gacgcccccaccttcccactgtgcctgcgcgcctacctcgccgatcgcctcggcttcggc
ctcgcctacgaccccgcgctgttcgaccgcgccaccgtggagcgcaccgcggaccggctg
cgggccctgctcaccgccgtcgccgacggcgccgcccggaccgtggacgacctcgacccg
ctcaccgacgccgaccgcgccctgctgcaccgctggaacaccccggcacgccagacgtcg
cccggttcaccggtgaccctcttcgccgagcaggtgcgccgcaccccggacgccctcgcc
gtcagcgacgacgagcaggagttgacgttccgtcaactcgacgaatgggccgacaagttg
gctcatcgtctgcgcgccgcggggctgcccgccgaggggcgggtggcgctgctcatggac
cgttcggtggccctcgtcgtggcccagctcgcggtcctcaaggccggcggcgcctacgtc
ccggtggacgtccgcgcccccgaggagcgccgccgcaccctgctccggcaggcgggggtc
acggtccagctgaccgaccgggacgtgaccgacgcccgcgccgacggcccggccggccca
ccgccggcagcggccaccgaccccgactgcctcgcgtacgtgatgttcacctccggatcg
accggtgagcccaaggccgtcggcgtgcgccaccgcgacgtggccgcgctcgccaccgac
agccgcttccggggccccgactgccaacgcgtcctgctgcactctcccgtggcgttcgac
gccgccaccttcgaggtctgggcgccgctgctgaacggcggccgcatcgtggtcgccccg
ccgggcgccgtgaacgcggccttgctgcggcggctggccgacgggggagaggtgaccgcg
ctgtggctgacggccgggctgttccggctgctggcacaggacgcgccggactgcttcgcg
ggactgcgccaggtgtggaccggcggcgacgtggtcccggccgcggccgtgcgccgggtc
ctcgacgcctgccccgggctgaccgtcgtggacggctacggcccgaccgagaccaccacc
ttcgccaccacccacgccatgaccgacgcggccgcggtacccgacccggtacccatcgga
cgccccctcgacgacatgcgggtgcacgtcctcgacgcccggctccggcccgtaccgccc
ggcaccgtcggcgagctctacctggccggcgagggcgtcgcccgcggctacctcggccgg
cccggagcgagtgccgaacgcttcctcgccgacccctccggcccgcccggcacccggatg
taccgcaccggcgacctcgcccgacggcaccccgacggcaccgtcgagttcctcggccgc
gccgacgatcaggtcaagatccgcggcttccgcgtcgaacccggcgaggtcgagggcgcc
ctggccgcccaccccgccgtcgcggacgtggccgtggtggcccgcgaaggacggtccggc
gcgaaacagctcatcgcctacgtcgtcggacacgacggactcgaccccgacgcgctgcac
gcccacgcccgccgcaccctgcccgactacctcgtgcccaccgccgtcgtcccgctggac
gcactgccgctcagcaccaacggcaaggtcgaccgggccgccctgccggcccccgacgcc
cccaccggccggccggaagccgtcgcaccgcgcaccgacgccgaacgccgcatcgccgcc
atctggtccgacgtactcggcgtacccgaagtcggcgtcacggacgacttcttcgccctc
ggcggcgactccatcctcagcatccggctcacctcgcggctcgcggaggcgttcggcacc
gagctgaccccgcgggcggtgttcagccacccgaccccggccgccctcgccgtgctgctc
accgcgcccgggcagcccgccggccggccgggcgcggcgctggtcccggtcggccgcgac
accccgctgccgcagtccttcgcccagcaacgcctgtggttcctggactcgttcgcgccg
gagagcaccgagtacctcaccccgctcgcgctgcggctgcgcggccgactggacaccacc
gcgctcgccgccgccctgaccgccctggccacccggcacgaatcgctgcgcaccaccttc
gactccgtcgacggccagggcgtccagatcgtccacccgccgcaggacgtcccgctgccg
ctgcacgacctgacggagctgccgcccggcgaccgcccggcgcggctaacgcagctgctc
gccgaagagcgcacccgccccttcgacctgcgccgcggacccctgctgcgggccgggctg
atccggctcgcggacgaccaccacgtcctgaccctgaccctgcaccacatcgtcaccgac
ggctggtcgaccggcatcctcaccggcgacctggcccacctctaccgcgccgcgctgacc
ggcacccccgccacgctgccggcgctgcccgtccagtacgccgatgtcgcccagtggcag
cgcaccgcgctcaccggcccggccgccgaggaccagctgcgctggtggaaggagcggctg
accggcatcgaaccgctccagctgcccaccgaccggccccggccaccggtccgcacccgg
cacggcgccacgaccgggttcgtcctgccgccggaaaccgcccgccggctcgccgagttc
ggccggacccggcagaccaccctgttcatgaccctggtcgccgcggtccagacgctcctc
gcccggctctccggacagcgggacatcgccgtcggcacggtcacctcgggccgcgaacgc
ccggaaacccagcgcctgatcggcttcttcgtcaacaccctggtgctgcgctccaccgtc
gaaccggagcggtccttcccggacttcctcgccgacgtccgtgacaccgtgctggacgcc
ttcgcgcaccaggacgtgccgttcgagcgggtcgtggacgaggtccagccggaccgcgac
accagccgcaccccgctcttccaggccatggtggtgctgcagaacgcccccggcgcgccg
atggacctgcccggcctccgggtcagcgacatcgagcccgagcgggacgaggccgccttc
gacgtcaccctggagttcgccgaggcggactccggcgccctgcacgggctgctcacctac
cattccgacctgttcgacgcggacaccgcacgccggatggccgaccagctcaccaccctg
ctcaccgccctcgccgacgaccccgaccgccccctcggcgcgctcccgctggcccccgcc
gaggaactgcggcgcctgctcaccgaccggcagggcgacgcgcaccgggtcccgccggcc
accctgcccgagctgttcgcacggcaggtcacccggcggcccgacgctccggccctcgcc
gagggcgaccgcgtgctgacctacgccgagctggacaccgccgccaaccgcctggcccac
cggctgatctcccgcggcgtcggcccggaacgcctggtcgccctggcgctgccgcgcggc
gccgacatggtcgtggcgcaactggcggtggccaaggccggcggcgcgttcctgcccgtc
gaccccgcctacccggccgagcgccgggagttcatggtccgcgactccgcggcggccctg
gtcctcgacgacccggcggacgtgtggtgccccgacggccccgcgaccgcccccaccgcc
gctgaccgcccggcccccctcaccaccgaccaccccgcctacgtcatctacacctccggc
tccaccggcacccccaaggccgtggtcgtgacgcacaccggactcgccggcttcgccgcg
gccgccgccgaccgctacgacgtacaacccggcgaccggatcctccagttcgcctcgccc
agcttcgacgcctccgtcctggagctgtgcatctccctgctcgccggcgccaccctgatc
gcgggggaggagggaccgctggtcggcgaccggctcgcccaggtgctcgccgaccggcgg
atcacccacaccctgatcccgcccgccgccctcgccaccgtcccgcccgaaacggccggc
accctgccggacctgcgcaccctcatcgtcggcgccgaggcctgcccggccgacctcgtc
gaccactgggccccgggccgccgcatgatcaactcctacggccccaccgaggccaccgtg
gtggccacctggaccggaccgctcactcccggcgcgggcgccccgcccatcggccacacc
gtcgacggcacccgcgcctacgtcctcgacgccgccctgcgccccgtaccggtcggcgtc
accggcgagttgtacgtggccggcgccggcctcgcccgcggctacctggcccgccccgga
ctgaccgccgcccgcttcccggccgaccccttcggcccgcccggcagccggatgtaccgc
accggagacctggtgcggtggggcgccgacggccaactccgctacgccggacgcgccgac
gaccaggtcaaggtccgcggctaccgcatcgaacccggcgagatcgagagcgcactgcgg
cgcgccccgcaggtccgggacgccgcggtcgtggtccgcagcaccggcccgtccggcgcc
gaaccacccgcccccggccggctggtcgcctacgtcgtccccgccgacgggccacccgac
gccctggacgtccaggaactgcgcgcggacctcgcccacaccctcccgtcccacatggtg
ccgtcggtgttcgtcccgctggcggagctgcccctcacccccaacggcaagaccgaccgc
cgggcgctgcccgctcccgccccgtccaccgtccccaccgcccaccacatcgccccgcgc
acggacaccgaacgccgtatcgcgcagatctgggccgaggtcctcggcctcgacaccgtg
ggcgccgatgacaacttcttcgccctcggcggcgactcgatcctcagcatgcaggtcgtc
tcacggctgcgccgcaccggactgcacctcgcgaccaaggacctgttcacccaccagacg
gtcgccgaactggccaccgtggtcaccaccggacccgaccgggccgacgacggcccggtc
accggcgacctgcccctcacccccatccagcactggttcctgaccaccccccgcgccaac
caccaccacttcaaccagtccgcactgctcgaactcgacggcgaacccgaccccaccgca
ctggaggcggcgctcaccgccctcctcacccaccacgacgccctccgcctgcgcttcacc
gaacaggacggccgctggcaccagcacaacccgcccccgcccgccaccccggaccgcctc
ctcgtccgccacgacctaaccggcctcacccccgaccagaccgacaccgccctccgcacc
accgccgacaccctgcacaccggcctcgacatcggccggggcccgctgctccgcgccgca
ctcctcaccggtggccgggaccaccccggctacctgctcctggtggcccaccacctcgtc
atcgacgcggtgtcctggcggatcctcctcgacgacctggacaccgcctaccaccaggcc
gcccagggccacccggtcacgctcggcgcccgcaccacctccttccgcgactgggcccgc
ggcctcgccgcacacgtcgccgcgggcgccctggaccacgaactcccttactgggaagag
gcattgaactccgccccgcttcccgtggaccacaccccggagcccgccaccaccgccgaa
accaggaccctgacccgcaccctggacgagcccgacaccaccgcactcctccgggccgcc
cccaccgcctaccgcacccgcatcaacgacgtcctgctcgccgccctcgccctcgccctg
gcccgctggaccgaccgggaccgggtctccgtggacctcgaaggacacggccgcgaggac
gtcctggacggcgtcgacctctcccgcaccgtcggctggttcaccaccgtccacccggtc
ggcctgcacatccccgatcgcgccgacctcggccccacccgggactggcgcgccctggtc
aagtccgtccgacgccaactccgcaccgttcccggcaacggcctcggcttcggcgccctg
cgcacgtacggcagcccggacatccgccggcgcctggagcgcaccggccacggccggctc
gtcttcaactacctcggccaatgggactcccgccgcacgggaaccgacaccggcggcggc
ctgatccgcgccgagcacggcagcttcggccaggaccacgacccccgcgaccccggctcc
cacctcctggaggcggtcggcgccgtccagaacggccgcctcaccttcacctggcactac
cgccccgacacccacgaggagaccaccgtccgcgccgtcgccgaggacttcaccgaggcc
ctccaccagatagcccggcacgcccgcaatagcctctga

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