Streptococcus pneumoniae 70585 (serotype 5): SP70585_1710
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Entry
SP70585_1710 CDS
T00872
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
snm
Streptococcus pneumoniae 70585 (serotype 5)
Pathway
snm00300
Lysine biosynthesis
snm00550
Peptidoglycan biosynthesis
snm01100
Metabolic pathways
snm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
snm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SP70585_1710
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SP70585_1710
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SP70585_1710
Enzymes [BR:
snm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SP70585_1710
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HBS1_N
Motif
Other DBs
NCBI-ProteinID:
ACO17675
UniProt:
C1C8Q9
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All DBs
Position
complement(1580045..1581418)
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AA seq
457 aa
AA seq
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MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFE
NGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAH
LLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAI
VTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTPADPIVEDYLPTDKKVVRFGQGA
ELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIHQAFQ
GLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKEL
GDQSIQLHNQIILSLSPDVLDTVIFYGEDIAELAQLASQMFPIGHVYYFKKTEDQDQFED
LVKQVKESLGAHDQILLKGSNSMNLAKLVESLENEDK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacaatctatgaagttgcccaagctgttggagctaaaaatgatgttagtctt
tttgcggacgcccagttagaaaaggctgagtttgacagtcgattgattgggactggagat
ttatttgtgccacttaaaggtgcgcgtgatggccatgactttattgaaacagcctttgaa
aatggtgcagcagtaaccttgtctgagaaagaggtctcaaatcatccttacattctagta
gatgatgttttgacagcctttcaatccttagcatcctactatcttgaaaaaacgactgtt
gatgtctttgctgttacaggttcaaatggcaagacaacgactaaggatatgttggcgcat
ttactgtcaacaagatacaagacctacaaaacacaaggcaattacaataatgagattggc
cttccttacacagttcttcatatgcctgaaggaacagaaaagttggttttggagatggga
caggatcacttgggagatattcatctcttgtctgaattggctcgtccaaaaacagccatc
gtgaccttggttggagaagctcatttggcctttttcaaagatcgttctgagattgctaaa
ggaaaaatgcaaattgcagacggaatggcttcaggttccttgcttttaacgccggctgac
cctatcgtagaggactatttgccaactgataaaaaggtggtccgttttgggcaaggggca
gagttggaaatcacagacttggttgagcgtaaggacagtctgacctttaaggctaatttc
ttggaacaagcccttgatttgccagtgactggtaagtacaatgctaccaatgctatgatt
gcgtcctatgttgccctacaagaaggagtttcagaggagcaaattcatcaggccttccaa
ggtcttgaattgacgcgtaatcgtactgagtggaagaaagcagccaatggagcagatatc
ctgtcagacgtatataatgccaatccaactgctatgaagctgattttagagactttctct
gccattccagccaatgaaggtggcaagaaaattgcagtgttggcggatatgaaggagctt
ggtgaccagtctattcaactccataaccagataattttgagcctttctccagatgtgctt
gataccgttattttctatggagaagacattgctgaattagcccaacttgctagtcaaatg
ttcccaatcggacacgtttattacttcaagaaaacagaagaccaagaccaatttgaagac
ctagttaagcaggtcaaagaaagccttggggctcatgaccaaatcctgctcaaaggctct
aactctatgaatctagccaagttggtagaaagtttagaaaatgaagacaagtga
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