Streptococcus pneumoniae AP200 (serotype 11A): SPAP_0459
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Entry
SPAP_0459 CDS
T01309
Name
(GenBank) thiamine pyrophosphate-requiring enzyme
KO
K01652
acetolactate synthase I/II/III large subunit [EC:
2.2.1.6
]
Organism
snp
Streptococcus pneumoniae AP200 (serotype 11A)
Pathway
snp00290
Valine, leucine and isoleucine biosynthesis
snp00650
Butanoate metabolism
snp00660
C5-Branched dibasic acid metabolism
snp00770
Pantothenate and CoA biosynthesis
snp01100
Metabolic pathways
snp01110
Biosynthesis of secondary metabolites
snp01210
2-Oxocarboxylic acid metabolism
snp01230
Biosynthesis of amino acids
Module
snp_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
snp_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
snp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
SPAP_0459
00660 C5-Branched dibasic acid metabolism
SPAP_0459
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SPAP_0459
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SPAP_0459
Enzymes [BR:
snp01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.6 acetolactate synthase
SPAP_0459
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Gene cluster
GFIT
Motif
Pfam:
TPP_enzyme_C
TPP_enzyme_M
TPP_enzyme_N
CO_dh
Motif
Other DBs
NCBI-ProteinID:
ADM84052
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Position
426078..427778
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AA seq
566 aa
AA seq
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MEKISLESPKTGSDLVLETLRNLGVDTIFGYPGGAVLPFYDAIYNFKGIRHILGRHEQGC
LHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPLLVFTGQVARAGIGKDAFQ
EADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRPGPVVIDLPKDISALETDFIY
SPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAGGGISYAEAATELNEFAERYQIP
VVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTEADFMISIGSRFDDRLTGNPKTFAK
NAKVAHIDIDPAEIGKIISADIPVVGDAKKALQMLLAEPTVHNNTEKWIEKVTKDKNRVR
SYDKKERVVQPQAVIERIGELTNGDAIVVTDVGQHQMWTAQYYPYQNERQLVTSGGLGTM
GFGIPAAIGAKIANPDKEVVLFVGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQ
WQESFYEGRTSESVFDTLPDFQLMAQAYGIKNYKFDNPETLAQDLEVITEDVPMLIEVDI
SRKEQVLPMVPAGKSNHEMLGVQFHA
NT seq
1701 nt
NT seq
+upstream
nt +downstream
nt
atggagaaaatcagtttagaatctcctaagacggggtcggacctagttttggaaacactt
cgtaatttaggagttgataccatctttggttatcctggtggtgcggttttgcctttttat
gatgcgatatataattttaaaggcattcgccacattctagggcgccatgagcaaggttgt
ttgcatgaagctgaaggttatgccaaatcaactggaaagttgggtgttgccgtcgtcact
agtggaccaggagcaacaaatgccattacagggattgcggatgccatgagcgatagcgtt
ccccttttggtctttacaggtcaggtggcgcgagcagggattgggaaggatgcctttcag
gaggcagacatcgtgggaattaccatgccaatcactaagtacaattaccaagttcgtgag
acagctgatattccgcgtatcattacggaagctgtccatatcgcaactacaggccgtcca
gggccagttgtaattgacctaccaaaagacatatctgctttagaaacagacttcatttat
tcaccagaagtgaatttaccaagttatcagccgactcttgagccgaatgatatgcaaatc
aagaaaatcttgaagcaattgtccaaggctaaaaagccagtcttgttagctggtggtgga
attagttatgctgaggctgctacggaactaaatgaatttgcagaacgctatcaaattcca
gtggtaaccagtcttttgggacaaggaacgattgcaacgagtcacccactctttcttgga
atgggaggcatgcacgggtcattcgcagcaaatattgctatgacggaagcggactttatg
attagtattggttctcgtttcgatgaccgtttgacggggaatcctaagactttcgctaag
aatgctaaggttgcccacattgatattgacccagctgagattggcaagattatcagtgca
gacattcctgtagttggagatgctaagaaggccttgcaaatgttgctagcagaaccaaca
gttcacaacaacactgaaaagtggattgagaaagtcactaaagacaagaatcgtgttcgt
tcttatgataagaaagagcgtgtggttcaaccgcaagcagttattgaacgaattggtgaa
ttgacgaatggagatgccattgtggtaacagacgttggtcaacaccaaatgtggacagct
cagtattatccctaccaaaatgaacgtcagttagtgacttcaggtggtttgggaacaatg
ggctttggaattccagcagcaatcggtgctaaaattgctaacccagataaggaagtagtc
ttgtttgttggggatggtggtttccaaatgaccaaccaggagttggctattttgaatatt
tacaaggtgccaatcaaggtggttatgctgaacaatcattcacttggaatggttcgccag
tggcaggaatccttctatgaaggcagaacatcagagtcggtctttgatacccttcctgat
ttccaattgatggcgcaggcttatggtattaaaaactataagtttgacaatcctgagacc
ttggctcaagaccttgaagtcatcactgaggatgttcctatgctaattgaggtagatatt
tctcgtaaggaacaggtgttaccaatggtaccggctggtaagagtaatcatgagatgttg
ggggtgcagttccatgcgtag
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