Streptomyces nodosus: CP978_19130
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Entry
CP978_19130 CDS
T06839
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
snq
Streptomyces nodosus
Pathway
snq00290
Valine, leucine and isoleucine biosynthesis
snq00770
Pantothenate and CoA biosynthesis
snq01100
Metabolic pathways
snq01110
Biosynthesis of secondary metabolites
snq01210
2-Oxocarboxylic acid metabolism
snq01230
Biosynthesis of amino acids
Module
snq_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
snq_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
snq00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP978_19130
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
CP978_19130
Enzymes [BR:
snq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
CP978_19130
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
QEV40382
UniProt:
A0A0B5DPA2
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Position
4234246..4236099
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSEAITEAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALVCI
SNCDKITPGMLMAALRLNIPTVFVSGGPMEAGRATLVDGTVRTLDLIDAIADAANDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARRALYEDAART
VMDLTRRYYEQDDDTVLPRTIATFPAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
EEIDRVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRGGLLNEEVHAVHSP
SLADWLKTWDVRGGSPSQEAVELWHAAPGCVRSADAFSQSERWEALDQDAENGCIRSVEH
AYSKDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVEKILAKQVKDGD
VVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKSCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVEDGDRIRIDIPNRSIELLVDDAELSRREQALGGVHAPKNRDRKVSAALRAYAA
MATSADRGAVRDISKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
ctgatgcgtgcctccggtgtacccggtgcggacatcggccggaagccgatcatcgcggtc
gccaactccttcacggagttcgtcccgggccacacccacctccagccggtcggccggatc
gtcagcgaggcgatcacggaggcggggggcatcccgcgcgagttcaacacgatcgcggtg
gacgacggcatcgccatggggcacggcggcatgctgtactccctgccctcccgcgatctg
atcgcggacagcgtggagtacatggtcgaggcccactgcgccgacgccctggtctgcatc
tccaactgcgacaagatcactccgggcatgctgatggcggcgctccgcctgaacatcccg
acggtcttcgtctccggcggtcccatggaggccgggcgggccaccctggtcgacggcacg
gtccgcacgctcgacctgatcgacgcgatcgccgacgccgccaacgacaagatctccgac
gaggacatcctccggatcgaggagaacgcctgtccgacctgcggctcctgttcgggcatg
ttcacggccaactcgatgaactgcctgaccgaggcgatcggactctcccttcccggcaac
ggctcggtcctggccacccacacggcccgccgcgcgctgtacgaggacgcggcccgcacg
gtgatggacctgacccgccgttactacgagcaggacgacgacacggtcctgccccgcacc
atcgccaccttcccggccttcgagaacgccatggccctcgacatcgcgatgggcggctcc
accaacacgatcctgcatctgctggcggcggcccaggaggcgggcgtccccttcggcctc
gaggagatcgaccgggtgtcgcgccgggtcccctgtctggcgaaggtggccccgaacgtc
gccaaggaccgcacctactacatggaggacgtgcaccgggccggcggcatccccgccctc
ctcggcgaactgcaccgtgggggcctgctcaacgaggaggtgcacgcggtccacagcccg
tccctcgcggactggctcaagacctgggacgtccgcggcggctccccctcgcaggaggcg
gtcgagctgtggcacgcggcgccgggatgtgtccggtccgccgacgccttctcccagtcc
gagcgctgggaggccctggaccaggacgccgagaacggctgtatccgctcggtcgagcac
gcgtactcgaaggacggcggcctggcggtcctcaggggcaatctcgccgtcgacggctgt
gtggtgaagacggcgggtgtcgacgagtcgatctggaccttcgagggtcccgcggtcgtc
tgcgagtcgcaggaggaggccgtcgagaagatcctcgccaagcaggtcaaggacggggac
gtggtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctat
ccgacctcgttcctcaagggccggggcctcgggaagtcctgcgcgctgatcaccgacggc
cgcttctccggcggcacctcgggcctgtccatcggccacgcctccccggaggcggcctcg
ggcggcacgatcgcgctcgtcgaggacggcgaccgcatccgcatcgacattccgaaccgc
tccatcgaactgctcgtcgacgacgcggagctgtcccgccgcgagcaggccctgggcggc
gtgcacgccccgaagaaccgcgaccgcaaggtgtcggcggcgctgcgggcctacgccgcg
atggccaccagcgccgaccggggcgccgtgcgcgacatctcgaaactgggctga
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