Streptomyces noursei ATCC 11455: SNOUR_29930
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Entry
SNOUR_29930 CDS
T04806
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
snr
Streptomyces noursei ATCC 11455
Pathway
snr00300
Lysine biosynthesis
snr00550
Peptidoglycan biosynthesis
snr01100
Metabolic pathways
snr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
snr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SNOUR_29930 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SNOUR_29930 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SNOUR_29930 (murF)
Enzymes [BR:
snr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SNOUR_29930 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ANZ19231
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Position
6765938..6767380
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AA seq
480 aa
AA seq
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MISLSLAEIASIVGGQQHDIPDPDREVTGPVVSDSRAVRPGGLFVAFAGERVDGHDFAVG
AVEAGAVAVLAARPVGVPAIVVDDVVAALGALARAVVNMSGATVVGLTGSAGKTSTKDLI
AQLLQRHGPTVWPEGNLNNEIGLPLTALRAEDTTRHLVLEMGARGIGHIRYLAGLTPPRI
GLVLNVGTAHLGEFGGREQIAQAKGELVESLPVAEDGGVAVLNADDPYVRAMASRTKART
VFFGESADAAIRAENVRLNGLGQPSFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMPVDEIAAALSEAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALVAMGAAGR
ARGGRTWAVLGEMAELGEESLAEHDAVGRLVVRLNVSKLVAVGGREAAWLDMGAKNEGSW
GEESVHVSDARAAIDLLRRELRPGDVVLVKASRSVGLERVAAALLDGEDGSAAKGGAASR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtccctcgccgagatcgcgagcatcgtcggcgggcagcagcacgacata
ccggacccggaccgcgaggtcaccgggccggtcgtgtcggactcccgggcggtccgcccg
ggtggcctgttcgttgcgttcgccggtgagcgcgtcgacggccacgacttcgccgtcggt
gccgtggaagccggtgcggtggccgtcctcgcggcccgcccggtcggcgtcccggcgatc
gtcgtcgacgacgtcgtcgcagctctcggcgcactcgcccgggccgtcgtgaacatgtcg
ggcgccaccgtcgtcggtctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctcctccagcggcacggtccgacggtgtggccggaaggcaacctcaacaacgag
atcgggctgccgctcaccgcgctgcgcgccgaggacaccacccggcacctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctcgccgggctgaccccgccccggatc
gggttggtcctcaacgtcggcaccgcgcacctcggcgagttcggcggccgcgagcagatc
gcccaggccaagggcgagctcgtcgagtcgttgccggtggcggaggacggcggcgtggcg
gtgctcaatgcggacgatccgtacgtccgggccatggcgtcccgtacgaaggcccgtacg
gtcttcttcggcgagtccgcggacgccgcgatccgcgccgagaatgtccggctcaacggc
ctcggacagccctccttcacgcttcacacaccctccgggtgcagtgatgtgaccatgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttg
ggcatgcccgtggacgagatcgccgccgcgctctccgaagccggcacgctctcccgctgg
cggatggaggtcaccgagcgcgcggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagcggcgctgcgtgcgctggtcgccatgggcgccgccggcagg
gcgcgggggggccggacgtgggcggtgctcggtgagatggccgagctgggcgaggagtca
ctcgccgaacacgacgcggtcgggcggctggtcgtccggctcaacgtcagcaagctcgtg
gcggtcggcggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcgatcgacctgttgcgcagggag
ctgcgaccgggagacgtcgtgctggtgaaggcgtccaggtcggtgggcctggagcgggtg
gccgcggcattgctggacggcgaggacggttccgctgcgaagggcggagccgcgtcccga
tga
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