KEGG   Streptococcus pneumoniae SPNA45 (serotype 3): SPNA45_00517
Entry
SPNA45_00517      CDS       T02245                                 
Symbol
mvaA
Name
(GenBank) 3-hydroxy-3-methylglutaryl-coenzyme A reductase
  KO
K00054  hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]
Organism
snu  Streptococcus pneumoniae SPNA45 (serotype 3)
Pathway
snu00900  Terpenoid backbone biosynthesis
snu01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:snu00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SPNA45_00517 (mvaA)
Enzymes [BR:snu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.88  hydroxymethylglutaryl-CoA reductase
     SPNA45_00517 (mvaA)
SSDB
Motif
Pfam: HMG-CoA_red
Other DBs
NCBI-ProteinID: CCM07807
LinkDB
Position
509417..510691
AA seq 424 aa
MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVADQLSENVVGIFSLPY
SLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQVHQRQMIGQVALYQVA
NPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIKGEPDFLVVYIHVDTQEA
MGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTASCRIAFRYLSRQKDQGREI
AEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGL
SCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHDLLGNPSARELAQIIVSIGLA
QNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAPLVEQLIADKTFNLETAQRYLE
NLRS
NT seq 1275 nt   +upstreamnt  +downstreamnt
atgaagataagttggaatggattttctaaaaaatcataccaagagcgcctcgagctgtta
aaagctcaggcgctccttagtcctgagagacaagctagtctggagaaggatgaacagatg
agcgtgactgtggcagaccagctgagtgagaatgtagtgggaattttttctctgccttat
tcactggttccggaggtacttgtcaacggtcaggaatacaccgttccctatgtgacagaa
gaaccctctgtggttgcggcggccagctatgccagcaaaatcatcaagcgtgcaggtggt
tttactgcacaagtccatcagcgacagatgattgggcaggtagccctttatcaagttgct
aatcctaaactagcgcaagagaagattgccagcaagaaagcggagctcttggagcttgcc
aatcaagcctatccttctatcgttaaacgtggaggtggggcgcgtgatctgcatgtcgag
cagataaaaggcgaaccagactttctcgttgtttatattcatgtcgatacccaggaagcc
atgggtgccaatatgctcaacaccatgctggaagccttgaaaccagtcttagaagaactc
agtcagggacagagtctcatgggaatcctgtccaactacgcgaccgattctctggtgact
gcaagctgtcgcatcgcctttcgctacttgagccgccaaaaggatcaaggacgagagatt
gcggagaaaattgcgttggctagtcagtttgcgcaggctgatccttaccgagctgctact
cataataaaggaatttttaatggtattgatgcgattttgattgccactggtaatgactgg
cgtgccatcgaagctggggcccatgcctttgccagtcgagatggacgctatcaaggtctt
agctgctggacgctggaccttgaaagagaagaattggtcggtgagatgaccctgcccatg
cctgtagcgactaagggtggctctatcggcctcaacccacgtgtagctctcagtcatgat
ctactaggaaatccttctgccagagaattagcccagattatcgtgtccatcggtcttgcc
caaaattttgcagccctcaaagccttggtaagtacgggcatccagcaaggccacatgaaa
ctacaggccaaatctctagctctcctagctggggctagtgaatctgaagttgctccccta
gtcgagcagcttatcgcagataaaacctttaacctagagacagcccagcgctatctcgaa
aatttaagatcataa

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