Streptococcus pneumoniae SPNA45 (serotype 3): SPNA45_01748
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Entry
SPNA45_01748 CDS
T02245
Symbol
folC
Name
(GenBank) putative putative folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
snu
Streptococcus pneumoniae SPNA45 (serotype 3)
Pathway
snu00790
Folate biosynthesis
snu01100
Metabolic pathways
snu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
snu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPNA45_01748 (folC)
Enzymes [BR:
snu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPNA45_01748 (folC)
6.3.2.17 tetrahydrofolate synthase
SPNA45_01748 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Polysacc_deac_2
Motif
Other DBs
NCBI-ProteinID:
CCM09033
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Position
complement(1779670..1780992)
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADYQSLLEGEAVANLQGTTEF
EIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQEMSLVTGRIAPEALAVIDRIAEGKDAPRLAYGTDYQVRHQESVVTGEVFD
YTSAVRQGRFQTSLLGLYQIENAGMAITLLDTFCQEDGRELASNDFLGQALEETSWPGRL
EIVSRDPLMILDGAHNPHAIKALLVTLQERFADYHKEILFTCIKTKALEDMLDLLGAMPD
TELTLTHFADSRATDESVLKEAAKSRNLSYQDWHDFLEQNLTDKKEEKQTIRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaacaatcagtggattgctaactaccggacggatcaaccgcatttt
ggcttggaacgaatggtggaactgttagctttgcgtggcaatccccatctcaaactcaag
gtcctccatatcggagggactaacggcaagggatcgactattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggcgtgtttagctcgccctatctcattcattacaca
gaccagattagcatcaatggggaatcgatctcagaagcgaggctagaagctctcatggca
gactatcagtctttgctggagggagaagcggtcgccaatttacagggcacaaccgagttt
gagattatcacagccctggcctatgactactttgcctcagagcaagtagatgtggccatc
atggaagttggcatgggtggacttttggatagtaccaatgtctgtcagcccattttgaca
ggaattacaactattggcttggatcatgtggccctacttggtgacaccttggaggccata
gcagagcagaaggcaggtattatcaaacaagagatgtccttggtaacagggcgtattgct
ccagaagccttggctgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggacagattatcaggttcgtcatcaagaaagtgtggtgacaggggaagtctttgac
tatacaagtgctgtcagacaaggtcgcttccagactagcctgcttggtttataccaaata
gagaatgctgggatggccataactttacttgatactttttgtcaagaagatggtcgagag
ctagcaagcaatgactttcttggccaagccttggaagaaacaagttggccaggacgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccacaatccccatgctatc
aaggccttgttggtaaccttgcaagaacgttttgcggattatcataaggaaatcctcttc
acttgtatcaaaaccaaggccttggaggatatgttggacttgctgggagccatgccagat
accgagcttactctaacacattttgcggatagtcgggcgacggatgaaagcgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcatgattttctagagcagaat
ttgacagataaaaaagaagagaaacaaacaattaggattgtcacaggttccttgtatttc
ttgagccaagtgagggcctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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