Streptomyces nigra: DC008_24955
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Entry
DC008_24955 CDS
T05839
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
snz
Streptomyces nigra
Pathway
snz00290
Valine, leucine and isoleucine biosynthesis
snz00660
C5-Branched dibasic acid metabolism
snz01100
Metabolic pathways
snz01110
Biosynthesis of secondary metabolites
snz01210
2-Oxocarboxylic acid metabolism
snz01230
Biosynthesis of amino acids
Module
snz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
snz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DC008_24955 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DC008_24955 (leuC)
Enzymes [BR:
snz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DC008_24955 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DC008_24955 (leuC)
SSDB
Ortholog
Paralog
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AWE52623
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All DBs
Position
5357288..5358718
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKTGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLEGRPHAPKGEDWDAAVAYWKTLRTDDDAEFDAEVVIDASALSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
LVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAETRTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctgcgcaagaccggtcgccgggtgcgccggctcgacctcaccatcgcgacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgcggaccccgtctcccgc
gtccagctggagaccctgcgcaagaacgccgccgagttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtccatgtcgtcggcccccagctgggtctgacccagccc
ggcatgaccgtggtctgcggcgactcgcacacctccacgcacggcgcgttcggcggcctg
gcgttcggcatcggcacctcccaggtggagcatgtgctggccacccagacgctgccgatg
gcccgcccgaagaccatggccatcacggtcgacggcgagctgcccgagggtgtcaccgcc
aaggacctgatcctcgcgatcatcgcgcggatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgaccagaccaccttc
gactacctcgagggccgcccgcacgcgcccaagggcgaggactgggacgccgccgtcgcg
tactggaagacgctgcggaccgacgacgacgccgagttcgacgccgaggtcgtcatcgac
gcctccgcgctgtcgccgttcgtcacctggggcaccaaccccggccagggcgctccgctt
tcggcgtccgtccccgacccggcttcgtacgaagacgcttcggagcgcctcgccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgcgctccatcaaggtggac
accgtcttcgtaggctcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctggtcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtcggtctgcaggccgtctcggagggcctggacgtcgtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctcggcgtccacgtccaaccgcaacttcgagggccggcagggcaagggcggc
cggacgcacctggtgtcgccgcaggtcgcggcggccaccgcggtcctgggccacctggcc
tccccggccgacctgtccgacgccgagacccgtacgcccgctggagtctga
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