Serratia odorifera: NCTC11214_00849
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Entry
NCTC11214_00849 CDS
T06612
Symbol
thrA_1
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sof
Serratia odorifera
Pathway
sof00260
Glycine, serine and threonine metabolism
sof00261
Monobactam biosynthesis
sof00270
Cysteine and methionine metabolism
sof00300
Lysine biosynthesis
sof01100
Metabolic pathways
sof01110
Biosynthesis of secondary metabolites
sof01120
Microbial metabolism in diverse environments
sof01230
Biosynthesis of amino acids
Module
sof_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sof_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sof00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC11214_00849 (thrA_1)
00270 Cysteine and methionine metabolism
NCTC11214_00849 (thrA_1)
00300 Lysine biosynthesis
NCTC11214_00849 (thrA_1)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC11214_00849 (thrA_1)
Enzymes [BR:
sof01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC11214_00849 (thrA_1)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC11214_00849 (thrA_1)
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Motif
Pfam:
ACT_9
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
VDZ52809
UniProt:
A0A447KMD0
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All DBs
Position
1:complement(770999..772996)
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AA seq
665 aa
AA seq
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MEEVFKARGFPVTVINPVEKLLAQGHYLESTVDIAESTLRIASAAIPADHIILMAGFTAG
NDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTVPDARLLKSMSYQE
AMELSYFGAKVLHPRTITPIAQFQIPCLIKNTANPQAPGTLIGGESVVDDTPVKGITNLN
NMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISFCVPQNELQRARRA
LGDEFYLELKDGLLEPLDVVENLAIISVVGDGMRTLRGISARFFTALARANINIVAIAQG
SSERSISVVVSNEDATTGVRVCHQMLFNTDQVIEVFVIGVGGVGGALIEQIYRQQPWLKQ
KHIDLRVCGIANSRAMLTDVHGIALDSWSEALAGAQEPFNLGRLIRLVKEYHLLNPVIVD
CTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNFYQQLRAAAAGSRRKFLYDTNVGAGL
PVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDEGMSLSAATLQAKANGYTEPDPRDD
LSGMDVARKLLILAREAGYKLELADIEVESVLPPGFDASGDVDTFLARLPALDEAFTRRV
ADATEQGKVLRYVGVIEEGRCQVRIDAVDGNDPLYKVKNGENALAFLQSLLSAIAVGVTR
LWRWQ
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atggaagaggtgttcaaggccagaggcttcccggtgacggtgatcaatccggtggaaaaa
ctgctggcgcaggggcactatctggagtctaccgtcgatattgccgagtccacgctgcgc
attgcttcggcagcgatcccggccgaccatatcatcctgatggccggctttaccgccggc
aacgacaagggcgagctggtggtgctggggcgtaacggctccgactattccgccgcggtg
ctggccgcctgcctgcgtgccgactgctgcgagatctggaccgacgtcgatggggtgtac
acctgcgatccgcgcaccgtaccggatgccaggctgctgaagtcgatgtcctatcaggaa
gcgatggaactgtcctatttcggcgccaaggtacttcacccccgcaccatcacgccgatt
gctcaattccagatcccctgcctgattaaaaatactgccaatccgcaagcgccaggcacc
ctgatcggcggtgaaagcgtggttgacgatacgccggtcaaaggcattaccaacctgaac
aacatggcgatgatcaacgtttccggcccaggcatgaaaggcatggttggcatggcggcg
cgggtgtttgccgtgatgtcgcgcgccggcatttcggtggtgctgatcacccagtcctct
tccgaatacagcatcagtttctgcgtaccgcaaaacgagctgcaacgcgctcgccgcgcg
ctgggcgatgagttctatctggaactgaaggatggcctgctggagccgctggacgtggtc
gaaaatctggcgatcatttcggtggttggcgatggcatgcgcacgctgcgcggtatttcg
gcgcgcttctttaccgcgctggcccgcgccaatatcaatatcgtggcgattgcgcagggc
tcctccgaacgttcgatctcggtggtggtcagtaacgaagacgccactaccggcgtgcgg
gtgtgtcaccagatgctgttcaacaccgatcaggtgattgaggtgttcgtgattggcgtc
ggcggcgttggcggcgcgctgatcgaacagatttatcgtcagcagccgtggctcaagcaa
aaacacatcgatttacgggtgtgcggcattgccaattcccgtgccatgctgaccgacgtc
catggcatcgcgctggacagctggagcgaggcgctggccggtgcgcaagagccgttcaat
ctggggcgtctgattcgcctggtgaaagagtaccatctgttgaatccggtgatcgtcgac
tgtacctccagccaggcggtggcggatcaatatgtcgacttcctggccgacggcttccat
gtggtcacgccgaataaaaaagccaatacctcgtcgatgaatttctaccaacagctgcgc
gcagccgctgccggatcgcgacgcaaattcctttacgataccaacgtcggcgccggcttg
ccggtgatcgaaaacctgcagaacctgctgaacgccggcgacgaactgacccgtttttcc
ggcatcctgtccggttcgctgtcatttatcttcggcaaactggatgaaggcatgtcgctg
tccgccgccaccctgcaggccaaggccaacggctataccgagccggatccgcgcgacgac
ctgtccggtatggacgtggcgcgcaaactgttgattttggcacgcgaagccggttacaaa
ttggagttggccgacatcgaggtggaatcggtgctgccgccaggctttgatgccagcggc
gatgtagacaccttcctggcgcgtttaccggcgctggacgaggcattcacccgtcgcgtg
gccgatgccacagaacagggcaaagtgctgcgctatgttggcgttatcgaagaggggcgc
tgtcaggtgcgtattgatgctgttgatggcaacgatccattatataaagtcaaaaacggc
gaaaacgcgctggcttttttacagtcgctattatcagccattgccgttggtgttacgcgg
ttatggcgctggcaatga
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