Streptococcus cristatus: I872_00735
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Entry
I872_00735 CDS
T02649
Name
(GenBank) dihydrofolate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
soi
Streptococcus cristatus
Pathway
soi00790
Folate biosynthesis
soi01100
Metabolic pathways
soi01240
Biosynthesis of cofactors
Module
soi_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
soi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
I872_00735
Enzymes [BR:
soi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
I872_00735
6.3.2.17 tetrahydrofolate synthase
I872_00735
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF3670
HHD_RTEL1
Motif
Other DBs
NCBI-ProteinID:
AGK70280
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Position
145636..146985
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AA seq
449 aa
AA seq
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MSMIKEELPDLSWLEAYRTDSPNFGLERMERMLALRGNPHLQLSVIHIGGTNGKGSTIAH
LRQLLEMRGLRVGTFTSPYLISYNEQIAINGQPISNQDLGRLLDTYRALFEEQAHDEVLQ
GVTEFEIMTALAYDYLAQERVDVAIMEVGMGGLLDSTNVCRPDLTAITTIGLDHVALLGH
SLAAIAEQKAGIIKPNVPLVTGRIEPEALAVIEYKAHQMQAPHYVYGQSYQVTSLGGTDS
GEHFSFSNAHREAEPYLTSLLGQHQVDNAGLAIQLCDLYCQSKQLPLLTKEQIDAALLAT
NWPGRMEQISHQPRIILDGAHNPHAMERLTRTLNQHYPDLDKKILFSCIQTKSLEEMVGQ
LKQVPKSQLILTSFADPRSFSKEKMEALACEQGLNYAAWQDFLEAYLKAEHRNDELLLIT
GSLYFLAQVRAYIIDKEKEHRSIYGHEEN
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atgagtatgataaaagaagaattgccagatttaagctggctggaagcctatcggacggat
agtcctaattttggcttggagcggatggagcggatgctggcgctgcggggaaatcctcat
ttgcagctgtcagtgattcatatagggggtaccaacgggaagggctcaaccattgcccac
ctgcgtcaactcttggaaatgcgaggtctgcgtgtgggaacctttacctccccctatctg
atcagctacaatgaacaaatcgccatcaatgggcagccgatttctaatcaggatttgggg
cgcctgctagatacttatcgagctctctttgaggagcaagcgcacgatgaggttttacaa
ggtgtgactgagtttgaaatcatgacagctttggcctatgattatttggctcaggagcga
gtcgatgtggccattatggaggtcggcatgggcggcctcttggacagtaccaatgtctgt
cgccctgatttgacagccattacgaccattggcttagatcatgtggctctgctggggcat
tctctggcagcaattgccgagcagaaagctgggattatcaagccaaatgtgcccttggtg
actgggcggattgagccagaagctctggcagttatcgagtacaaagctcatcaaatgcaa
gccccccactatgtgtacggtcaatcttatcaagtgacaagcttgggagggactgactca
ggagagcattttagcttttccaatgcccatcgggaggcggagccctatctgacgtctctg
ttaggacaacatcaggtagataatgctggtttggcgattcagctctgtgacctctattgt
cagagcaagcagctaccgcttttaacaaaagagcaaatagacgccgctttactggcgaca
aactggccggggcggatggagcagatttcgcaccagcctcgcatcattctcgatggcgcc
cacaatcctcatgctatggagagattgacgaggactttgaaccaacattatccagacctg
gataagaaaatcctttttagctgtatccagaccaagtctctggaggaaatggtaggtcaa
ctcaagcaagtacctaagagtcagctgattttgaccagttttgcagatccacggagcttt
tccaaagaaaaaatggaggcgctggcttgcgagcagggcttgaactatgctgcttggcaa
gactttttagaggcttatttgaaagctgagcataggaacgatgagcttttgctgattacg
ggttctctttattttctggctcaggtcagggcctatatcattgacaaagaaaaagaacat
aggagtatatatggacacgaagaaaattga
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