Streptomyces okerensis: ACE1N8_25525
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Entry
ACE1N8_25525 CDS
T11145
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
soke Streptomyces okerensis
Pathway
soke00290
Valine, leucine and isoleucine biosynthesis
soke00660
C5-Branched dibasic acid metabolism
soke01100
Metabolic pathways
soke01110
Biosynthesis of secondary metabolites
soke01210
2-Oxocarboxylic acid metabolism
soke01230
Biosynthesis of amino acids
Module
soke_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
soke00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ACE1N8_25525 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACE1N8_25525 (leuC)
Enzymes [BR:
soke01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ACE1N8_25525 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ACE1N8_25525 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
XKV07331
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Position
5650245..5651675
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKNGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPRTMAITVNGELPDGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAVEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRPHAPKGEDWDAAVAYWKTLRSDEDAEFDAEVVIEAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDPSERFAAEKALEYMGLEAGQELRSISVDTVFVGSCTNGRIEDLRAAAD
IIGGRKVAEGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLAAADARTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggcctccgcaagaacggccgcccggtgcgccgtctcgacctcaccatcgccacc
gaggaccacaacacccccaccctcgacatcgacaagccgatcgccgacccggtctcccgg
gtccagctggagacgctgcgcaagaactgcgcggacttcggtgtccggctgcacccgctg
ggcgacgtcgagcagggtgtcgtccacgtcgtcggcccgcagctgggtctgacccagccc
ggtatgaccgtcgtctgcggtgactcgcacacttccacgcacggcgccttcggcggactg
gcgttcggcatcggcacctcccaggtggagcacgtcctggccacccagacgctgccgatg
gcccgccccaggaccatggcgatcacggtcaacggcgaactgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggtacgggcggcggccagggctatgtc
ctggagtaccgcggcgaggccgtcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagacgacgttc
gcctacctcgagggccgcccgcacgccccaaagggcgaggactgggacgcggccgtcgcc
tactggaagacgctcaggtccgacgaggacgccgagttcgacgccgaggtggtcatcgag
gccgccgaactgtcgccgttcgtcacctggggcaccaacccgggccagggcgccccgctc
tccgcgtccgtccccgacccggcttcgtacgaagacccctcggagcggttcgccgccgaa
aaggccctggagtacatggggttggaggccggccaggagctgcgctccatcagcgtggac
accgtcttcgtagggtcctgcaccaacggccgcatcgaggacctgcgtgccgccgccgac
atcatcggcggccgcaaagtcgccgagggcgtacggatgctggtcgtcccgggctccgcg
cgggtgggtctgcaggccgtctccgaggggctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctccatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctccgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgtacccacctggtgtccccgcaggtcgccgccgccaccgcggtcctcggccacctggcc
tccccggccgacctcgccgcagccgacgcccgtacgcccgctggagtctga
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