Entry Name Bacterial chemotaxis - Shewanella oneidensis
Description Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class Cellular Processes; Cell motilityBRITE hierarchy
Pathway map Other DBs Organism Shewanella oneidensis [GN:
son ]
Gene SO_1529 pomA; stator-force generator of Na+ coupled flagellar motor PomA [KO:K02556 ]
SO_1530 pomB; stator-force generator of Na+ coupled flagellar motor PomB [KO:K02557 ]
SO_1989 cheV; chemotaxis signal transduction system response regulator CheV [KO:K03415 ]
SO_2120 cheY; chemotaxis signal transduction system response regulator CheY [KO:K03413 ]
SO_2122 cheW; chemotaxis signal transduction system adaptor protein CheW [KO:K03408 ]
SO_2125 cheD; chemotaxis signal transduction system chemoreceptor glutamine deamidase CheD [KO:K03411 ] [EC:3.5.1.44 ]
SO_2126 cheB; chemotaxis signal transduction system response regulator with glutamate methylesterase domain CheB [KO:K03412 ] [EC:3.1.1.61 3.5.1.44 ]
SO_2318 cheY; chemotaxis signal transduction system response regulator CheY [KO:K03413 ]
SO_2324 cheW; chemotaxis signal transduction system adaptor protein CheW [KO:K03408 ]
SO_2326 cheD; chemotaxis signal transduction system chemoreceptor glutamine deamidase CheD [KO:K03411 ] [EC:3.5.1.44 ]
SO_2327 cheB; chemotaxis signal transduction system response regulator with glutamate methylesterase domain CheB [KO:K03412 ] [EC:3.1.1.61 3.5.1.44 ]
SO_2546 cheC; chemotaxis signal transduction system inhibitor of MCP methylation CheC [KO:K03410 ]
SO_3123 cheV; chemotaxis signal transduction system response regulator CheV [KO:K03415 ]
SO_3202 cheW; chemotaxis signal transduction system adaptor protein CheW [KO:K03408 ]
SO_3203 cheW; chemotaxis signal transduction system adaptor protein CheW [KO:K03408 ]
SO_3206 cheB; chemotaxis signal transduction system response regulator with glutamate methylesterase domain CheB [KO:K03412 ] [EC:3.1.1.61 3.5.1.44 ]
SO_3208 cheZ; chemotaxis signal transduction system CheY phosphatase CheZ [KO:K03414 ]
SO_3209 cheY; chemotaxis signal transduction system response regulator CheY [KO:K03413 ]
SO_3220 fliN; flagellar motor switching and energizing component FliN [KO:K02417 ]
SO_3221 fliM; flagellar motor switching and energizing component FliM [KO:K02416 ]
SO_3227 fliG; flagellar motor switching and energizing component FliG [KO:K02410 ]
SO_3252 cheV; chemotaxis signal transduction system response regulator CheV [KO:K03415 ]
SO_3915 cheX; chemotaxis signal transduction system CheY dephosphorylase CheX [KO:K03409 ]
SO_4286 motB; stator-force generator of H+ coupled flagellar motor MotB [KO:K02557 ]
SO_4287 motA; stator-force generator of H+ coupled flagellar motor MotA [KO:K02556 ]
Compound Reference Authors Kristich CJ, Ordal GW.
Title Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
Journal Reference Authors Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
Title CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
Journal Reference Authors Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
Title Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
Journal Reference Authors Szurmant H, Muff TJ, Ordal GW.
Title Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
Journal Reference Authors Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
Title Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
Journal Reference Authors Darzins A.
Title The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
Journal Reference Authors Szurmant H, Ordal GW
Title Diversity in chemotaxis mechanisms among the bacteria and archaea.
Journal Reference Authors Rao CV, Glekas GD, Ordal GW
Title The three adaptation systems of Bacillus subtilis chemotaxis.
Journal Reference Authors Muff TJ, Ordal GW
Title The diverse CheC-type phosphatases: chemotaxis and beyond.
Journal Reference Authors Miller LD, Russell MH, Alexandre G
Title Diversity in bacterial chemotactic responses and niche adaptation.
Journal Related KO pathway
