Streptococcus pyogenes NZ131 (serotype M49): Spy49_0146
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Entry
Spy49_0146 CDS
T00780
Symbol
slo
Name
(GenBank) Thiol-activated cytolysin
KO
K11031
thiol-activated cytolysin
Organism
soz
Streptococcus pyogenes NZ131 (serotype M49)
Pathway
soz02024
Quorum sensing
Brite
KEGG Orthology (KO) [BR:
soz00001
]
09140 Cellular Processes
09145 Cellular community - prokaryotes
02024 Quorum sensing
Spy49_0146 (slo)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02042 Bacterial toxins [BR:
soz02042
]
Spy49_0146 (slo)
Bacterial toxins [BR:
soz02042
]
Type II toxins: Membrane damaging toxins
Pore-forming toxins, Beta-pore-forming/Cholesterol-dependent
Spy49_0146 (slo)
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Gene cluster
GFIT
Motif
Pfam:
Thiol_cytolysin
Thiol_cytolys_C
DUF6479
Motif
Other DBs
NCBI-ProteinID:
ACI60495
UniProt:
A0A0H3BYW1
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Position
155786..157501
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AA seq
571 aa
AA seq
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MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTIE
KAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNE
LEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDMTYPAALQL
ADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNY
SGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQI
FYTVSANLPNNPADVFDKSVTFKDLQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSND
VEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIKDNA
TFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQYEIL
WDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRK
VIDERDVKLSKEINVNISGSTLSPYGSITYK
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgtctaataaaaaaacatttaaaaaatacagtcgcgtcgctgggctactaacggcagct
cttatcattggtaatcttgttactgctaatgctgaatcgaacaaacaaaacactgctagt
acagaaaccacaacgacaaatgagcaaccaaaaccagaaagtagtgagctaactatcgaa
aaagcaggtcagaaaatggatgatatgcttaactctaacgatatgattaagcttgctccc
aaagaaatgccactagaatctgcagaaaaagaagaaaaaaagtcagaagacaaaaaaaag
agcgaagaagatcacactgaagaaatcaatgacaagatttattcactaaattataatgag
cttgaagtacttgctaaaaatggtgaaaccattgaaaattttgttcctaaagaaggcgtt
aagaaagctgataaatttattgtcattgaaagaaagaaaaaaaatatcaacactacacca
gtcgatatttccatcattgactctgtcactgatatgacctatccagcagcccttcagctg
gctgataaaggttttaccgaaaacaaaccagacgcggtagtcaccaagcgaaacccacaa
aaaatccatattgatttaccaggtatgggagacaaagcaacggttgaggtcaatgaccct
acctatgccaatgtttcaacagctattgataatcttgttaaccaatggcatgataattat
tctggtggtaatacgcttcctgccagaacacaatatactgaatcaatggtatattctaaa
tcacagattgaagcagctctaaatgttaatagcaaaatcttagatggtactttaggcatt
gatttcaagtcgatttcaaaaggtgaaaagaaggtgatgattgcagcatacaagcaaatt
ttttacaccgtatcagcaaaccttcctaataatcctgcggatgtgtttgataaatcagtg
acctttaaagatttacaacgaaaaggtgtcagcaatgaagctccgccactctttgtgagt
aacgtagcctatggtcgaactgtttttgtcaaactagaaacaagttctaaaagtaatgat
gttgaagcggcctttagtgcagctctaaaaggaacagatgttaaaacgaatggaaaatac
tctgatatcttagaaaatagttcatttacagctgtcgttttaggaggagatgctgcagag
cacaataaggtagtcacaaaagactttgatgttattagaaacgttatcaaagacaatgct
accttcagtagaaaaaacccagcttatcctatttcatacaccagtgttttccttaaaaat
aataaaattgcgggtgtcaataacagaactgaatatgttgaaacaacatctaccgagtac
actagtggaaaaattaacctgtctcatcgaggcgcgtatgttgctcaatatgaaatcctt
tgggatgaaatcaattatgatgacaaaggaaaagaagtgattacaaaacgacgttgggac
aacaactggtatagtaagacatcaccatttagcacagttatcccactaggagctaattca
cgaaatatccgtatcatggctagagagtgcaccggcttagcttgggaatggtggcgaaaa
gtgatcgacgaaagagatgtgaaactgtctaaagaaatcaatgtcaacatctcaggatca
accctgagcccatatggttcgattacttataagtag
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