Streptococcus pyogenes NZ131 (serotype M49): Spy49_0745
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Entry
Spy49_0745 CDS
T00780
Symbol
rmlB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
KO
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
Organism
soz
Streptococcus pyogenes NZ131 (serotype M49)
Pathway
soz00521
Streptomycin biosynthesis
soz00523
Polyketide sugar unit biosynthesis
soz00525
Acarbose and validamycin biosynthesis
soz00541
Biosynthesis of various nucleotide sugars
soz01100
Metabolic pathways
soz01110
Biosynthesis of secondary metabolites
soz01250
Biosynthesis of nucleotide sugars
Module
soz_M00793
dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
soz00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
Spy49_0745 (rmlB)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
Spy49_0745 (rmlB)
01055 Biosynthesis of vancomycin group antibiotics
Spy49_0745 (rmlB)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
Spy49_0745 (rmlB)
00525 Acarbose and validamycin biosynthesis
Spy49_0745 (rmlB)
Enzymes [BR:
soz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.46 dTDP-glucose 4,6-dehydratase
Spy49_0745 (rmlB)
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GFIT
Motif
Pfam:
GDP_Man_Dehyd
Epimerase
NAD_binding_4
3Beta_HSD
Polysacc_synt_2
RmlD_sub_bind
NAD_binding_10
NmrA
adh_short
Sacchrp_dh_NADP
KR
Motif
Other DBs
NCBI-ProteinID:
ACI61059
UniProt:
A0A0H3C086
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All DBs
Position
748570..749610
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AA seq
346 aa
AA seq
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MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAILGDRVELVVGD
IADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFIGTYTLLEAARKYDIRFHH
VSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGVK
ATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTGVWAILT
KGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTKLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atgtataaaaatattatcgtaactggtggagctggtttcatcggttctaactttgtacac
tatgtctacaataaccacccagatgttcatgtaactgtccttgataaattgacatatgca
ggtaaccgtgctaacattgaagctattcttggtgatcgtgttgagttagttgttggtgat
atcgctgacgctgaattggtagacaaattggctgccaaagcggatgctattgttcactat
gcggctgagagccacaacgataactcattggaagatccaagtccatttatccatacaaac
tttatcggaacttacactttgcttgaagcagctcgtaaatacgatatccgtttccaccac
gtgtcaactgatgaagtttatggagatcttccacttcgtgaagaccttccaggacagggt
gaaggaccaggtgaaaaattcactgctgaaacaaaatacaatccatcatcaccttactca
tcaactaaggcagcttctgaccttatcgttaaggcatgggtacgttccttcggtgtgaaa
gcgaccatttcgaactgttcaaataactatggaccataccaacacatcgaaaaattcatt
ccacgtcaaattacaaatatcttggcaggaatcaaaccaaaactttatggtgaaggtaaa
aacgtccgtgactggattcatactaatgatcattctacaggagtatgggctattttgact
aagggtcgtatcggtgaaacataccttattggtgccgacggcgagaaaaacaacaaggaa
gttcttgaattgattcttgaaaaaatgggtcaaccaaaagacgcttatgatcacgtaact
gaccgtgctggtcacgatcttcgttacgctattgattctacaaaattgcgtgaagaactc
ggctgggaaccacaatttacaaacttttcagaaggtttggaagaaactattaagtggtat
acagaaaatgagacatggtggaaagcagaaaaagatgctgtagaagccaagtatgctaaa
actcaagaagtgattaaataa
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