Streptococcus pyogenes NZ131 (serotype M49): Spy49_0915
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Entry
Spy49_0915 CDS
T00780
Symbol
topA
Name
(GenBank) Putative DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
soz
Streptococcus pyogenes NZ131 (serotype M49)
Brite
KEGG Orthology (KO) [BR:
soz00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
soz03032
]
Spy49_0915 (topA)
03400 DNA repair and recombination proteins [BR:
soz03400
]
Spy49_0915 (topA)
Enzymes [BR:
soz01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
Spy49_0915 (topA)
DNA replication proteins [BR:
soz03032
]
Prokaryotic type
DNA Topoisomerases
Spy49_0915 (topA)
DNA repair and recombination proteins [BR:
soz03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
Spy49_0915 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_Top1
Toprim
C1_2
DUF2996
Toprim_4
HypA
Motif
Other DBs
NCBI-ProteinID:
ACI61221
UniProt:
A0A0H3C059
LinkDB
All DBs
Position
911028..913157
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AA seq
709 aa
AA seq
DB search
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDL
KKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHI
LGLDPQDNNRVVFNEITKDAVKHAFVKPRQIDMDLVDSQQARRVLDRIVGYSISPILWKK
VKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDGLFKKGTKKFQATFYGINGKKTK
LDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMV
AQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTS
GAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQN
GVIFVANGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEAT
LIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVA
FTAEMEGKLDQVEIGEEEWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGH
PMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQY
PDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
ttgggaacaaaaactacaactaagccaaaaacgggtactaaaaagtccaccactaaaaag
aaatcaacagcgaaaaaaaatctcgttattgttgaatcacctgccaaagctaagactatt
gaaaaatatcttggacgcagttataaagttgttgcttcggtaggacatattcgtgactta
aaaaaatcgtctatgtctattgattttgataataattatgagccgcaatacattaatatc
cgtggtaagggaccccttatcaattctttaaaaaaagaagccaaagctgctaaaaaagtt
tatttagctagtgacccggatcgtgagggagaggctatttcttggcatttgtcacatatc
ttaggacttgatcctcaagataataaccgagtggtttttaatgaaattacgaaagatgca
gttaaacatgcctttgtgaagcctcgtcagattgatatggacttggtagattctcaacaa
gcacgtcgtgttttagaccgtattgtgggatattccatttcaccaattctttggaaaaag
gtcaaaaaaggactttcagcaggacgtgtccagtcggttgctttaaaactcatcattgac
cgtgaaaatgacatcaaagcatttgttccaaaggaatactggtctattgatggtcttttt
aaaaaaggaactaaaaagtttcaagcgactttttacggtattaatggcaaaaaaacaaag
cttgataataacaacgatgtcaaagaggtattagcaaagctaacaaatgaagattttctt
gtcagcaaggttgacaagaaagagcgacgtcgtaatgctcccttaccttacacaacatca
tctcttcaacaagatgctgctaataaaatcaatttcagaacgcgtaaaaccatgatggta
gcccaacaactgtatgaggggattcatttaggagaaaatggaactcaaggtttaattacc
tatatgcgtacggattctactcgtatcagtccagtagcacaaaacgatgctgctcaattt
attatcaatcgctttggagctaattattcaaaacatggtaatcgtgtcaaaaataccagt
ggtgcccaagatgctcacgaggcgattcgtccatctagtgttaatcatacgccagactct
attgccaaatacctcaacaaggatcagttaaaactttatacgcttatttggaatcgtttt
gtggctagccaaatgacagcagctgtttttgataccgtaaaggtgaacttggagcaaaat
ggcgtgatttttgttgccaatggtagccaaatgaagtttgatggttacatggctgtttac
aatgattccgataaaaacaaaatgttacctgagatggcagaaggagaaacggttaaaaaa
atatcgacctctccagaacagcactttacgcagccaccagctcgttattctgaagcaact
ctgattaaaactttagaagaaaatggggtcggtcgaccatcaacttatgccccaacctta
gaagtgattcaacgcaggtactatgttaaattatctgctaagcgctttgagccaactgag
cttggggaaattgtcaacaagcttattgtcgaatttttcccagatattgttgatgttgcc
tttactgccgagatggaaggtaagctagatcaagttgaaatcggtgaagaagaatggcaa
catgtcatcgatcaattctatcaaccctttgtcaaagaattgaataaggctgagtctgaa
attgaaaagattcaaatcaaagatgagccagctggttttgactgtgatgtttgtggccac
ccaatggtcattaagttaggacgttttgggaaattttatgcgtgtagcaacttcccagag
tgccgtaatacaaaagccatcactaaagaaattggtgttacttgtccggtttgtcataaa
ggacaagttatcgagcgtaaaaccaaaaaaaataggatattttatggttgtgatcagtat
ccagattgtgagtttatctcgtgggatttacctattggacgtgcttgccctaagtcaggt
gactatcttattgagaaaaaagttcgtggtggcaaacaagtaatgtgtagcaatgagacc
tgtgattacaaggaagaaaaaattaaataa
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