Streptococcus pyogenes MGAS10394 (serotype M6): M6_Spy0072
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Entry
M6_Spy0072 CDS
T00191
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spa
Streptococcus pyogenes MGAS10394 (serotype M6)
Pathway
spa00230
Purine metabolism
spa01100
Metabolic pathways
spa01110
Biosynthesis of secondary metabolites
Module
spa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M6_Spy0072
Enzymes [BR:
spa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
M6_Spy0072
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Paralog
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Motif
Other DBs
NCBI-ProteinID:
AAT86207
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Position
77637..81410
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AA seq
1257 aa
AA seq
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MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDRLLTEAEITAELDKVAFFAIEALPGQFDQRAASSQEAL
LLFGSDSQVKVNTAELYLINKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFENYKADDFAAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRTGKLPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGEVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGETIVDLERRFLDTNGVRVVVDVKFVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTRTASVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADIRKVLSPEFKAAGENIYY
IPGQAISEDIDFDLIKANFSQFEAIQAQHKITAASAAKYGSVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEE
VYPTEFEQADALEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEVAIAESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGSLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggatttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggcattaaatcggctagccttgtgaaagagttg
acacataatctacaactgacttctttgaaggacttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttactggcgcgtgctgagaagcatattttctctgagcaggtg
acagaccgtcttttgacggaagctgaaatcactgcggagcttgataaggttgccttcttt
gccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagctgagctatacttgatcaat
aaggatattgcagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtatctgataag
acgatccctaatcttgatttctttgaaaattataaagctgacgattttgcggcctataag
gcagagcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttcaaa
tcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacaacttatgataaatatatcgccatgcgtgatgagcttggt
cgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaatgagact
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtactggtaaattgccacaacaggttatt
tctaagactgcggcgcacggctattcttcatatggtaaccaaattggacttgcgacaact
tatgtgcgtgagtacttccaccctggcttcgtagccaaacgcatggagcttggagctgtg
gtcggagcggcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggtgatgtggta
atcttgcttggtggtaaaacagggcgtgacggtgtcggcggtgcgacaggttcatctaag
gttcaaacggttgagtctgtggaaacagctggcgcagaggtacaaaaagggaatgccatc
gaagagcgtaagattcaacgtctcttccgtgatggtgaagtgactcgtctcatcaaaaaa
tcaaacgactttggtgctggtggtgtctgtgttgctatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtcccacttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaagtgatgtggatgccttc
atcgcagcttgcaacaaggaaaatatcgatgccgttgtagttgcgacagttaccgagaaa
ccaaatcttgtcatgacttggaatggtgaaaccatcgttgacttggaacgccgtttcctt
gataccaacggtgtccgtgtcgttgttgatgttaaattcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gatctcaaccatgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgc
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaagaacagcatctgttatggctcaaggttac
aatccttatattgctgagtggtcaccttaccacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgacaaca
gcggacatccgcaaggttctctctcctgagtttaaagcggctggcgaaaacatttactat
atcccaggtcaagctatttcagaagatattgattttgaccttatcaaggctaactttagc
cagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
agtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgaccttgctggcgctagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaattcgaacaggcagacgctcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattcctgtcttc
cctggtaccaactcagaatatgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgacactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggcttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtagccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaagaagctggtgagacaagt
ccaactctcttctataacgatgccaaccaacacgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccatccca
gtttcacacggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatattcctggt
aacaaagaccaaaccttgtttgctagtgcagtaaaatattttacaggaaaataa
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