Streptococcus pyogenes MGAS10394 (serotype M6): M6_Spy0078
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Entry
M6_Spy0078 CDS
T00191
Name
(GenBank) Phosphoribosylamine--glycine ligase
KO
K01945
phosphoribosylamine---glycine ligase [EC:
6.3.4.13
]
Organism
spa
Streptococcus pyogenes MGAS10394 (serotype M6)
Pathway
spa00230
Purine metabolism
spa01100
Metabolic pathways
spa01110
Biosynthesis of secondary metabolites
Module
spa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M6_Spy0078
Enzymes [BR:
spa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
M6_Spy0078
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
GARS_N
GARS_C
ATP-grasp_3
CPSase_L_D2
ATP-grasp
ATP-grasp_2
ATP-grasp_4
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-ProteinID:
AAT86213
UniProt:
Q5XEF0
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Position
87890..89302
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AA seq
470 aa
AA seq
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MANRVFLISRIVVYYHIFTMFQLLIINTLYQKANVYDIISNYNTKEVGVLKLLVVGSGGR
EHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDLVNIVVSEHSRLIAFAKENEISWAFIGP
DDALAAGIVDDFNSAGLRAFGPTKAAAELEWSKDFAKEIMVKYNVPTAAYGTFSDFEKAK
AYIEEQGAPIVVKADGLALGKGVVVAETVEQAVEAAQEMLLDNKFGDSGARVVIEEFLDG
EEFSLFAFVNGDKFYIMPTAQDHKRAFDGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIV
RPVLEGMVAEGRPYLGVLYVGLILTADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDD
IMMGIEPYITWQNDGVTLGVVVASEGYPLDYEKGVPLPEKTDGDIITYYAGAKFAENSEL
LLSNGGRVYMLVTTEDSVKAGQDKIYTQLAQQDTTGLFYRNDIGNKAIKE
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
ttggctaatagagtgttccttatttcaagaattgtggtctactatcacatttttacaatg
tttcaattattgataattaatacattgtatcaaaaggcgaacgtttatgatataatatct
aattataatacgaaagaggtgggtgttttgaaattacttgttgttggttcaggtggtcgt
gaacatgcgattgctaagaagttgttagcgtctaagggtgtggatcaggtttttgtggca
cctggtaatgatggtatgaccttggatggtctggacttggtgaatatagtagtttccgaa
cattccaggttgattgcctttgcgaaggagaatgagatttcttgggcctttattggtcct
gatgatgcgctagcagctggtatcgttgatgatttcaacagtgctggactcagagctttt
ggtccaacaaaggcagcagcggagctagagtggtcaaaagactttgccaaggaaatcatg
gtcaaatacaatgtcccaacagcagcctatggcacattttcagactttgaaaaagccaaa
gcctacatcgaagagcagggcgcacctatcgtggtcaaggctgatggcttggcgctaggt
aagggtgtggtcgtggctgaaaccgttgagcaggcggtagaggcggcgcaagagatgctt
ctggacaataagtttggcgactcaggagcgcgtgtggttatcgaggaattcttggatggc
gaggagttttccctctttgcctttgttaatggtgataagttctacatcatgccgacagct
caggatcacaagcgtgcctttgacggagacaaggggccaaacactggtggtatgggtgcc
tatgcgccagttcctcatctacctcagagcgtggtagacacagcggttgagacgatcgtt
aggcctgtccttgagggcatggttgccgaagggcgtccttatctaggtgtcctttatgtg
gggcttatcctgacagctgatggacctaaggttatcgagttcaactcacgtttcggtgac
cctgaaactcagattatcctccctcgtctgacttccgatttcgctcagaatattgacgat
atcatgatgggcattgagccttacatcacttggcagaatgacggtgtgactttgggtgtt
gtcgttgcctcagaaggctatccactcgattatgagaaaggtgtgccactgcctgaaaag
accgacggcgatatcatcacctactatgccggagctaagtttgcggaaaatagcgagcta
cttctctcaaacggaggacgtgtctatatgcttgtcaccacagaagacagcgtcaaagca
gggcaggacaaaatctatacccaactggcccaacaagacacaacaggtctcttctaccga
aatgacatcggaaacaaagctattaaagaataa
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